Two faces of arbutin in hepatocellular carcinoma (HepG2) cells: Anticarcinogenic effect in high concentration and protective effect against cisplatin toxicity through its antioxidant and anti-inflammatory activity in low concentration

The anticarcinogen activity of β-arbutin on MCF-7 cells: Stimulation of apoptosis through estrogen receptor-α signal pathway, inflammation and genotoxicity

(2020) Ömer Hazman et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Liver function and DNA integrity in hepatocytes of rats evaluated after treatments with strawberry tree (Arbutus unedo L.) water leaf extract and arbutin

(2018) Karlo Jurica et al.   DRUG AND CHEMICAL TOXICOLOGY

The Effect of Boric Acid and Borax on Oxidative Stress, Inflammation, ER Stress and Apoptosis in Cisplatin Toxication and Nephrotoxicity Developing as a Result of Toxication

(2018) Ömer Hazman et al.   INFLAMMATION

Oleuropein potentiates anti-tumor activity of cisplatin against HepG2 through affecting proNGF/NGF balance

(2018) Iman O. Sherif et al.   LIFE SCIENCES

Recent progress on biological production of α-arbutin

(2018) Xingtong Zhu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells

(2017) Liyan Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

High-level De novo biosynthesis of arbutin in engineered Escherichia coli

(2017) Xiaolin Shen et al.   METABOLIC ENGINEERING

Action of tyrosinase on alpha and beta-arbutin: A kinetic study

(2017) Antonio Garcia-Jimenez et al.   PLoS One

Comparison of the Anti-inflammatory Effects of Proanthocyanidin, Quercetin, and Damnacanthal on Benzo(a)pyrene Exposed A549 Alveolar Cell Line

(2016) Ersin Günay et al.   INFLAMMATION

Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on the safety of the use of α-arbutin in cosmetic products

(2016) SCCS et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway

(2016) Ping Wang et al.   Oncology Letters

Opinion of the Scientific Committee on Consumer Safety (SCCS) – Opinion on the safety of the use of β-arbutin in cosmetic products

(2015) SCCS et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells

(2014) Li-Hua Wu et al.   APOPTOSIS

Anticancer Effects of Thymoquinone, Caffeic Acid Phenethyl Ester and Resveratrol on A549 Non-small Cell Lung Cancer Cells Exposed to Benzo(a)pyrene

(2014) Sevinc Sarinc Ulasli et al.   Asian Pacific Journal of Cancer Prevention

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytotoxic impact of phenolics from Lamiaceae species on human breast cancer cells

(2013) Izabela Berdowska et al.   FOOD CHEMISTRY

Anti-inflammatory effects of arbutin in lipopolysaccharide-stimulated BV2 microglial cells

(2012) Hyo-Jong Lee et al.   INFLAMMATION RESEARCH

Role of metabolism by the human intestinal microflora in arbutin-induced cytotoxicity in HepG2 cell cultures

(2011) Tilak Khanal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reassessment of antioxidant activity of arbutin: Multifaceted evaluation using five antioxidant assay systems

(2010) Jun Takebayashi et al.   FREE RADICAL RESEARCH

Increase the cisplatin cytotoxicity and cisplatin-induced DNA damage in HepG2 cells by XRCC1 abrogation related mechanisms

(2009) Rong Zhang et al.   TOXICOLOGY LETTERS

Proteomics analysis of A375 human malignant melanoma cells in response to arbutin treatment

(2008) Jiraporn Nawarak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS