Curcuma longa and curcumin affect respiratory and allergic disorders, experimental and clinical evidence: A comprehensive and updated review

Oral nano‐curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease ‐19 patients: An open label nonrandomized clinical trial

(2021) Niloofar Saber‐Moghaddam et al.   PHYTOTHERAPY RESEARCH

Experimental and clinical reports on anti‐inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive review

(2021) Arghavan Memarzia et al.   BIOFACTORS

Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease

(2021) Sebastian T Lugg et al.   THORAX

Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial

(2021) Kirti S Pawar et al.   Frontiers in Pharmacology

Radiation induced apoptosis and pulmonary fibrosis: curcumin an effective intervention?

(2020) Shilpa Johnson et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Facile synthetic nano-curcumin encapsulated Bio-fabricated nanoparticles induces ROS-mediated apoptosis and migration blocking of human lung cancer cells

(2020) Yuehua Dong et al.   PROCESS BIOCHEMISTRY

Therapeutic Efficacy of Curcumin Enhanced by Microscale Discoidal Polymeric Particles in a Murine Asthma Model

(2020) Jun Young Park et al.   Pharmaceutics

Curcumin-loaded niosomes downregulate mRNA expression of pro-inflammatory markers involved in asthma: an in vitro study

(2020) Jin-Ying Wong et al.   Nanomedicine

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

(2019) Ahlame Saidi et al.   Scientific Reports

Hydro-ethanolic extract of Curcuma longa affects tracheal responsiveness and lung pathology in ovalbumin-sensitized rats

(2019) Farzaneh Shakeri et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells

(2019) Cuijuan Wang et al.   Future Oncology

Design and synthesis novel di-carbonyl analogs of curcumin (DACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI)

(2019) Jianchang Qian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Curcumin Attenuates Asthmatic Airway Inflammation and Mucus Hypersecretion Involving a PPARγ-Dependent NF-κB Signaling Pathway In Vivo and In Vitro

(2019) Tao Zhu et al.   MEDIATORS OF INFLAMMATION

Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial

(2019) Gabriel Manarin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell death

(2019) Ping Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Direct pulmonary delivery of solubilized curcumin reduces severity of lethal pneumonia

(2019) Boya Zhang et al.   FASEB JOURNAL

Immunomodulatory and Anti-Inflammatory Potential of Curcumin for the Treatment of Allergic Asthma: Effects on Expression Levels of Pro-inflammatory Cytokines and Aquaporins

(2019) Hira Shahid et al.   INFLAMMATION

Effect of curcumin nanomicelle on the clinical symptoms of patients with rheumatoid arthritis: A randomized, double‐blind, controlled trial

(2019) Maryam Javadi et al.   International Journal of Rheumatic Diseases

Curcumin ameliorates chronic obstructive pulmonary disease by modulating autophagy and endoplasmic reticulum stress through regulation of SIRT1 in a rat model

(2019) Feng Tang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Curcumin Ameliorates Ovalbumin-Induced Atopic Dermatitis and Blocks the Progression of Atopic March in Mice

(2019) Sukriti Sharma et al.   INFLAMMATION

Curcumin potentiates the galbanic acid-induced anti-tumor effect in non-small cell lung cancer cells through inhibiting Akt/mTOR signaling pathway

(2019) Qian Zhang et al.   LIFE SCIENCES

A novel synthetic curcumin derivative MHMM-41 induces ROS-mediated apoptosis and migration blocking of human lung cancer cells A549

(2018) Guang-Zhou Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin Attenuates Airway Inflammation and Airway Remolding by Inhibiting NF-κB Signaling and COX-2 in Cigarette Smoke-Induced COPD Mice

(2018) Jin Yuan et al.   INFLAMMATION

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

(2018) Jianping Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin affects tracheal responsiveness and lung pathology in asthmatic rats

(2018) Farzaneh Shakeri et al.   Pharmacological Reports

Intranasal curcumin regulates chronic asthma in mice by modulating NF-ĸB activation and MAPK signaling

(2018) Preeti S Chauhan et al.   PHYTOMEDICINE

Superior anticancer activity is demonstrated by total extract of Curcuma longa L. as opposed to individual curcuminoids separated by centrifugal partition chromatography

(2018) Wirginia Kukula-Koch et al.   PHYTOTHERAPY RESEARCH

Curcumin Attenuates Pulmonary Inflammation in Lipopolysaccharide Induced Acute Lung Injury in Neonatal Rat Model by Activating Peroxisome Proliferator-Activated Receptor γ (PPARγ) Pathway

(2018) Keping Cheng et al.   MEDICAL SCIENCE MONITOR

Curcumin Inhibits Growth of Human NCI-H292 Lung Squamous Cell Carcinoma Cells by Increasing FOXA2 Expression

(2018) Lingling Tang et al.   Frontiers in Pharmacology

Inhalation treatment of primary lung cancer using liposomal curcumin dry powder inhalers

(2018) Tongtong Zhang et al.   Acta Pharmaceutica Sinica B

Inhalation treatment of idiopathic pulmonary fibrosis with curcumin large porous microparticles

(2018) Yuzhen Hu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Curcumin ameliorates atherosclerosis in apolipoprotein E deficient asthmatic mice by regulating the balance of Th2/Treg cells

(2018) Shanshan Gao et al.   PHYTOMEDICINE

Inhibitory effects of bisdemethoxycurcumin on mast cell-mediated allergic diseases

(2018) Meng Fu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection through inhibiting the NF-κB signaling pathway

(2017) Yiming Xu et al.   Influenza and Other Respiratory Viruses

Curcumin converts Foxp3+ regulatory T cells to T helper 1 cells in patients with lung cancer

(2017) Jian Y. Zou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Curcumin Inhibits LIN-28A through the Activation of miRNA-98 in the Lung Cancer Cell Line A549

(2017) Wei-Lun Liu et al.   MOLECULES

Synergistic antiviral effect of curcumin functionalized graphene oxide against respiratory syncytial virus infection

(2017) Xiao Xi Yang et al.   Nanoscale

Relaxant effect of Curcuma longa on rat tracheal smooth muscle and its possible mechanisms

(2017) Bahman Emami et al.   PHARMACEUTICAL BIOLOGY

Curcumin use in pulmonary diseases: State of the art and future perspectives

(2017) Diana Lelli et al.   PHARMACOLOGICAL RESEARCH

Curcumin, an antibiotic resistance breaker against a multiresistant clinical isolate of Mycobacterium abscessus

(2017) Emanuela Marini et al.   PHYTOTHERAPY RESEARCH

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways

(2017) Jian-Yun Zhu et al.   PHYTOTHERAPY RESEARCH

Effect of curcumin on nasal symptoms and airflow in patients with perennial allergic rhinitis

(2016) Sihai Wu et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Antioxidant activities of curcumin in allergic rhinitis

(2016) Niyazi Altıntoprak et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats

(2016) Heping Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma

(2016) Preeti S. Chauhan et al.   INFLAMMATION

Intranasal curcumin ameliorates airway inflammation and obstruction by regulating MAPKinase activation (p38, Erk and JNK) and prostaglandin D2 release in murine model of asthma

(2016) Subhashini et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin reduces lung inflammation via Wnt/β-catenin signaling in mouse model of asthma

(2016) Xia Yang et al.   JOURNAL OF ASTHMA

Can curcumin modulate allergic rhinitis in rats?

(2016) M Acar et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY

Curcumin ameliorates alveolar epithelial injury in a rat model of chronic obstructive pulmonary disease

(2016) Ming Zhang et al.   LIFE SCIENCES

Curcumin modified silver nanoparticles for highly efficient inhibition of respiratory syncytial virus infection

(2016) Xiao Xi Yang et al.   Nanoscale

DIFFERENTIAL SUSCEPTIBILITY OF HUMAN SP-B GENETIC VARIANTS ON LUNG INJURY CAUSED BY BACTERIAL PNEUMONIA AND THE EFFECT OF A CHEMICALLY MODIFIED CURCUMIN

(2016) Yongan Xu et al.   SHOCK

Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model

(2016) Xingli Gan et al.   International Journal of Chronic Obstructive Pulmonary Disease

Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD

(2016) Tatsuya Morimoto et al.   International Journal of Chronic Obstructive Pulmonary Disease

The inhibitory effect of Curcuma longa extract on telomerase activity in A549 lung cancer cell line

(2016) Mohammad Pourhassan et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

Anti-inflammatory effect of curcumin on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse

(2015) Ning Zhang et al.   CELLULAR IMMUNOLOGY

Curcumin alleviates lung injury in diabetic rats by inhibiting nuclear factor-κB pathway

(2015) Fang Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Curcumin induces the apoptosis of non-small cell lung cancer cells through a calcium signaling pathway

(2015) XUDONG XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effect of curcumin (Curcuma longa extract) on LPS-induced acute lung injury is mediated by the activation of AMPK

(2015) Joungmin Kim et al.   Journal of Anesthesia

Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type 1/type 2 helper T cells (Th1/Th2) balance in a mouse model of food allergy

(2015) Hee Soon Shin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair

(2015) Maryam Mohajeri et al.   NEUROPHARMACOLOGY

Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway

(2015) LICHUAN WU et al.   ONCOLOGY REPORTS

Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway

(2015) HAI JIN et al.   ONCOLOGY REPORTS

The oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol

(2015) Alexa Kocher et al.   Journal of Functional Foods

Curcumin Inhibits Non-Small Cell Lung Cancer Cells Metastasis through the Adiponectin/NF-κb/MMPs Signaling Pathway

(2015) Jong-Rung Tsai et al.   PLoS One

Curcumin attenuatesstaphylococcus aureus-induced acute lung injury

(2014) Feng Xu et al.   Clinical Respiratory Journal

Intranasal Curcumin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2014) Asha Kumari et al.   INFLAMMATION

Protective Effect of Curcumin on Acute Airway Inflammation of Allergic Asthma in Mice Through Notch1–GATA3 Signaling Pathway

(2014) Lei Chong et al.   INFLAMMATION

Intranasal curcumin attenuates airway remodeling in murine model of chronic asthma

(2014) Preeti S. Chauhan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Structure-activity relationship analysis of curcumin analogues on anti-influenza virus activity

(2013) Jun-Lin Ou et al.   FEBS Journal

Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice

(2013) Chunhua Ma et al.   FITOTERAPIA

Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs

(2013) Vishnu N. Thakare et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway

(2013) Qing-yong Chen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Mouse Model of Viral-induced Acute Respiratory Distress Syndrome

(2013) Sreedevi Avasarala et al.   PLoS One

Renoprotective effect of the antioxidant curcumin: Recent findings

(2013) Joyce Trujillo et al.   Redox Biology

Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models

(2012) Adriana Monserrath Orellana-Paucar et al.   EPILEPSY & BEHAVIOR

Enhanced bioavailability and efficiency of curcumin for the treatment of asthma by its formulation in solid lipid nanoparticles

(2012) Wenrui Wang et al.   International Journal of Nanomedicine

Multitargeting by turmeric, the golden spice: From kitchen to clinic

(2012) Subash C. Gupta et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis

(2012) Binu Chandran et al.   PHYTOTHERAPY RESEARCH

Curcumins-Rich Curry Diet and Pulmonary Function in Asian Older Adults

(2012) Tze Pin Ng et al.   PLoS One

Anti-inflammatory effects of curcumin in a murine model of chronic asthma

(2011) M. Karaman et al.   ALLERGOLOGIA ET IMMUNOPATHOLOGIA

Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice

(2011) Laxmidhar Das et al.   BIOSCIENCE REPORTS

Upregulation of p53 Expression in Patients with Colorectal Cancer by Administration of Curcumin

(2011) Zhen-Yu He et al.   CANCER INVESTIGATION

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury

(2010) Monica R. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma

(2010) Maha E. Houssen et al.   CLINICAL BIOCHEMISTRY

Quality and antioxidant properties of bread containing turmeric (Curcuma longa L.) cultivated in South Korea

(2010) Ho S. Lim et al.   FOOD CHEMISTRY

Clinical Study of Turmeric (Curcuma longa L.) and Garlic (Allium sativum L.) Extracts as Antihyperglycemic and Antihyperlipidemic Agent in Type-2 Diabetes-Dyslipidemia Patients

(2010) E.Y. Sukandar et al.   International Journal of Pharmacology

Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice

(2010) S. Bansal et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice

(2009) S.J. Moghaddam et al.   CARCINOGENESIS

Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production

(2009) Lin Xie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin Attenuates Airway Hyperresponsiveness and Inflammation in Murine Asthma Model

(2009) J. Lee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparative antiulcer effect of Bisdemethoxycurcumin and Curcumin in a gastric ulcer model system

(2009) S. Mahattanadul et al.   PHYTOMEDICINE

Curcumin Restores Corticosteroid Function in Monocytes Exposed to Oxidants by Maintaining HDAC2

(2008) Koremu K. Meja et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

(2008) Dipti Rai et al.   BIOCHEMICAL JOURNAL

Modulation of steroid activity in chronic inflammation: A novel anti-inflammatory role for curcumin

(2008) Saibal Biswas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Antidepressant activity of curcumin: involvement of serotonin and dopamine system

(2008) Shrinivas K. Kulkarni et al.   PSYCHOPHARMACOLOGY

Effect of NCB-02, Atorvastatin and Placebo on Endothelial Function, Oxidative Stress and Inflammatory Markers in Patients with Type 2 Diabetes Mellitus

(2008) P Usharani et al.   Drugs in research & development