Modulation of CD36 ‐mediated lipid accumulation and senescence by vitamin E analogs in monocytes and macrophages

Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis

(2021) Jun Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation

(2020) Eun-Jeong Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro

(2020) Jia Liu et al.   Cell Discovery

Reduction of senescence‐associated beta‐galactosidase activity by vitamin E in human fibroblasts depends on subjects’ age and cell passage number

(2020) Roberta Ricciarelli et al.   BIOFACTORS

Dexamethasone Sodium Phosphate Loaded Modified Cyclodextrin Based Nanoparticles: An Efficient Treatment for Rheumatoid Arthritis

(2020) Dhananjay Jadhav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

(2020) Sourish Ghosh et al.   CELL

Nanomaterials fusing with the skin: Alpha-tocopherol phosphate delivery into the viable epidermis to protect against ultraviolet radiation damage

(2020) Mais M. Saleh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21

(2019) Valerie M. Harris et al.   Frontiers in Immunology

Targeting macrophages and their recruitment in the oral cavity using swellable (+) alpha tocopheryl phosphate nanostructures

(2019) Robert A. Harper et al.   Nanomedicine-Nanotechnology Biology and Medicine

CD36 initiates the secretory phenotype during the establishment of cellular senescence

(2018) Mengyang Chong et al.   EMBO REPORTS

Water-soluble all-rac α-tocopheryl-phosphate and fat-soluble all-rac α-tocopheryl-acetate are comparable vitamin E sources for swine

(2018) Theo A T G van Kempen et al.   JOURNAL OF ANIMAL SCIENCE

Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation

(2018) Keagan P. Collins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Vitamin E: Regulatory Role on Signal Transduction

(2018) Jean-Marc Zingg   IUBMB LIFE

Antioxidant Vitamin E/Cyclodextrin Inclusion Complex Electrospun Nanofibers: Enhanced Water Solubility, Prolonged Shelf Life, and Photostability of Vitamin E

(2017) Asli Celebioglu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Tocopheryl Phosphate Induces VEGF Expression via CD36/PI3Kγ in THP-1 Monocytes

(2017) Jean-Marc Zingg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of lipids is central to replicative senescence

(2017) Darleny Y. Lizardo et al.   Molecular BioSystems

2-Hydroxypropyl-beta-cyclodextrin (HPβCD) reduces age-related lipofuscin accumulation through a cholesterol-associated pathway

(2017) Jason Gaspar et al.   Scientific Reports

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

(2016) Brandon M. Hall et al.   Aging-US

The enigmatic membrane fatty acid transporter CD36: New insights into fatty acid binding and their effects on uptake of oxidized LDL

(2016) Anthony G. Jay et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

(2016) Sebastian Zimmer et al.   Science Translational Medicine

Vitamin E: A Role in Signal Transduction

(2015) Jean-Marc Zingg   Annual Review of Nutrition

Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases

(2015) M. A. A. Al-Bari   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Induction of VEGF Expression by Alpha-Tocopherol and Alpha-Tocopheryl Phosphate via PI3Kγ/PKB and hTAP1/SEC14L2-Mediated Lipid Exchange

(2015) Jean-Marc Zingg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice

(2015) Anke Schloesser et al.   Oxidative Medicine and Cellular Longevity

Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function

(2014) Adam M Lopez et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin

(2014) Jean E. Vance et al.   JOURNAL OF LIPID RESEARCH

Fluorescently Labeled Methyl-Beta-Cyclodextrin Enters Intestinal Epithelial Caco-2 Cells by Fluid-Phase Endocytosis

(2014) Ferenc Fenyvesi et al.   PLoS One

Modulation of Phosphorylation of Tocopherol and Phosphatidylinositol by hTAP1/SEC14L2-Mediated Lipid Exchange

(2014) Jean-Marc Zingg et al.   PLoS One

Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium

(2014) M. M. Nociari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Transport of Fat-Soluble Vitamins A and E

(2014) Nozomu Kono et al.   TRAFFIC

Vitamin E Dietary Supplementation Improves Neurological Symptoms and Decreases c-Abl/p73 Activation in Niemann-Pick C Mice

(2014) Tamara Marín et al.   Nutrients

Vitamin E Trafficking in Neurologic Health and Disease

(2013) Lynn Ulatowski et al.   Annual Review of Nutrition

Impaired  -TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency

(2013) N. Kono et al.   SCIENCE

Computational microscopy of cyclodextrin mediated cholesterol extraction from lipid model membranes

(2013) Cesar A. López et al.   Scientific Reports

α-tocopheryl-phosphate regulation of gene expression in preadipocytes and adipocytes

(2012) Melania Lirangi et al.   BIOFACTORS

α-Tocopheryl phosphate-An activated form of vitamin E important for angiogenesis and vasculogenesis?

(2012) Jean-Marc Zingg et al.   BIOFACTORS

Development of a method for oral administration of hydrophobic substances to Caenorhabditis elegans: pro-longevity effects of oral supplementation with lipid-soluble antioxidants

(2012) Noriko Kashima et al.   BIOGERONTOLOGY

Structure and physicochemical properties of octenyl succinic anhydride modified starches: A review

(2012) Michael C. Sweedman et al.   CARBOHYDRATE POLYMERS

Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease

(2012) Jiaqi Yao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin

(2012) Mark A. Crumling et al.   PLoS One

Acidic Nanoparticles Are Trafficked to Lysosomes and Restore an Acidic Lysosomal pH and Degradative Function to Compromised ARPE-19 Cells

(2012) Gabriel C. Baltazar et al.   PLoS One

Lysosomal Acidification Mechanisms

(2011) Joseph A. Mindell   Annual Review of Physiology

The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

(2011) Kai Xiao et al.   BIOMATERIALS

Selection of reliable reference genes during THP-1 monocyte differentiation into macrophages

(2011) Marten B Maeß et al.   BMC MOLECULAR BIOLOGY

α-Tocopheryl phosphate: Uptake, hydrolysis, and antioxidant action in cultured cells and mouse

(2011) Keiko Nishio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Altered vitamin E status in Niemann-Pick type C disease

(2011) L. Ulatowski et al.   JOURNAL OF LIPID RESEARCH

Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and Is Prevented by Driving Cholesterol Export from This Compartment

(2011) A. Aqul et al.   JOURNAL OF NEUROSCIENCE

The enhancement of the oral bioavailability of γ-tocotrienol in mice by γ-cyclodextrin inclusion

(2011) Noriyuki Miyoshi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Promotion of plasma membrane repair by vitamin E

(2011) Amber C. Howard et al.   Nature Communications

Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction

(2011) Cesar A. López et al.   PLoS Computational Biology

Complexation of Tocotrienol with γ-Cyclodextrin Enhances Intestinal Absorption of Tocotrienol in Rats

(2010) Saiko IKEDA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Release characteristics of vitamin E incorporated chitosan microspheres and in vitro–in vivo evaluation for topical application

(2010) E. Yenilmez et al.   CARBOHYDRATE POLYMERS

Effect of tocopheryl phosphate on key biomarkers of inflammation: Implication in the reduction of atherosclerosis progression in a hypercholesterolaemic rabbit model

(2010) Roksan Libinaki et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Mammalian diseases of phosphatidylinositol transfer proteins and their homologs

(2010) Aaron H Nile et al.   Clinical Lipidology

Modulation of gene expression by α-tocopherol and α-tocopheryl phosphate in THP-1 monocytes

(2010) Jean-Marc Zingg et al.   FREE RADICAL BIOLOGY AND MEDICINE

PREPARATION AND SPECTRA PROPERTIES OF INCLUSION COMPLEXES OF VITAMIN E WITH β-CYCLODEXTRIN

(2010) FEI PENG JIAO et al.   JOURNAL OF FOOD PROCESSING AND PRESERVATION

Analysis of vitamin E metabolites in biological specimen

(2010) Marc Birringer   MOLECULAR NUTRITION & FOOD RESEARCH

Molecular mechanisms of membrane transport of vitamin E

(2010) Tappei Takada et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

(2010) A. I. Rosenbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclodextrin Inclusion Complex Formation and Solid-State Characterization of the Natural Antioxidants α-Tocopherol and Quercetin

(2009) John L. Koontz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid

(2009) Benny Liu et al.   JOURNAL OF LIPID RESEARCH

Study of the cholesterol extraction capacity of β-cyclodextrin and its derivatives, relationships with their effects on endothelial cell viability and on membrane models

(2008) Delphine Castagne et al.   JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

(2008) Gabriel Schaaf et al.   MOLECULAR CELL