Degeneracy in the nervous system: from neuronal excitability to neural coding

Ion Channel Degeneracy, Variability, and Covariation in Neuron and Circuit Resilience

(2021) Jean-Marc Goaillard et al.   Annual Review of Neuroscience

Simulating lesion-dependent functional recovery mechanisms

(2021) Noor Sajid et al.   Scientific Reports

Robust emergence of sharply tuned place-cell responses in hippocampal neurons with structural and biophysical heterogeneities

(2020) Reshma Basak et al.   Brain Structure & Function

Neuro-Clinical signatures of language impairments: A theoretical framework for function-to-structure mapping in clinics

(2020) Ferath Kherif et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Degeneracy in the emergence of spike-triggered average of hippocampal pyramidal neurons

(2020) Abha Jain et al.   Scientific Reports

Circuit Stability to Perturbations Reveals Hidden Variability in the Balance of Intrinsic and Synaptic Conductances

(2020) Sebastian Onasch et al.   JOURNAL OF NEUROSCIENCE

Temperature compensation in a small rhythmic circuit

(2020) Leandro M Alonso et al.   eLife

Degeneracy and Redundancy in Active Inference

(2020) Noor Sajid et al.   CEREBRAL CORTEX

Network level characteristics in the emotion recognition network after unilateral temporal lobe surgery

(2020) Yun‐An Huang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Efficient sensory coding of multidimensional stimuli

(2020) Thomas E. Yerxa et al.   PLoS Computational Biology

A unified neurocomputational bilateral model of spoken language production in healthy participants and recovery in poststroke aphasia

(2020) Ya-Ning Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal morphologies built for reliable physiology in a rhythmic motor circuit

(2019) Adriane G Otopalik et al.   eLife

Degeneracy in hippocampal physiology and plasticity

(2019) Rahul K. Rathour et al.   HIPPOCAMPUS

Network degeneracy and the dynamics of task switching in the feeding circuit in Aplysia

(2019) Yanqing Wang et al.   JOURNAL OF NEUROSCIENCE

The neural and neurocomputational bases of recovery from post-stroke aphasia

(2019) James D. Stefaniak et al.   Nature Reviews Neurology

On the origin of degeneracy in the genetic code

(2019) D. L. Gonzalez et al.   Interface Focus

Degeneracy in the robust expression of spectral selectivity, subthreshold oscillations and intrinsic excitability of entorhinal stellate cells

(2018) Divyansh Mittal et al.   JOURNAL OF NEUROPHYSIOLOGY

Origin of heterogeneous spiking patterns from continuously distributed ion channel densities: a computational study in spinal dorsal horn neurons

(2018) Arjun Balachandar et al.   JOURNAL OF PHYSIOLOGY-LONDON

Concurrent Changes of Brain Functional Connectivity and Motor Variability When Adapting to Task Constraints

(2018) Grégoire Vergotte et al.   Frontiers in Physiology

Disparate forms of heterogeneities and interactions among them drive channel decorrelation in the dentate gyrus: Degeneracy and dominance

(2018) Poonam Mishra et al.   HIPPOCAMPUS

The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow

(2018) Rosanna Migliore et al.   PLoS Computational Biology

Degeneracy in the regulation of short-term plasticity and synaptic filtering by presynaptic mechanisms

(2017) Chinmayee L. Mukunda et al.   JOURNAL OF PHYSIOLOGY-LONDON

Navigating the Neural Space in Search of the Neural Code

(2017) Mehrdad Jazayeri et al.   NEURON

Neuroscience Needs Behavior: Correcting a Reductionist Bias

(2017) John W. Krakauer et al.   NEURON

The theory of constructed emotion: an active inference account of interoception and categorization

(2017) Lisa Feldman Barrett   Social Cognitive and Affective Neuroscience

Strings on a Violin: Location Dependence of Frequency Tuning in Active Dendrites

(2017) Anindita Das et al.   Frontiers in Cellular Neuroscience

Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion

(2017) Adriane G Otopalik et al.   eLife

When complex neuronal structures may not matter

(2017) Adriane G Otopalik et al.   eLife

Neuronal Firing Rate Homeostasis Is Inhibited by Sleep and Promoted by Wake

(2016) Keith B. Hengen et al.   CELL

Selection Maintains Apparently Degenerate Metabolic Pathways due to Tradeoffs in Using Methylamine for Carbon versus Nitrogen

(2016) Dipti D. Nayak et al.   CURRENT BIOLOGY

Afferent hyperexcitability in neuropathic pain and the inconvenient truth about its degeneracy

(2016) Stéphanie Ratté et al.   CURRENT OPINION IN NEUROBIOLOGY

Homeostatic Activity-Dependent Tuning of Recurrent Networks for Robust Propagation of Activity

(2016) Julijana Gjorgjieva et al.   JOURNAL OF NEUROSCIENCE

Quantification of degeneracy in Hodgkin–Huxley neurons on Newman–Watts small world network

(2016) Menghua Man et al.   JOURNAL OF THEORETICAL BIOLOGY

Clinical Concepts Emerging from fMRI Functional Connectomics

(2016) Paul M. Matthews et al.   NEURON

Bats perceptually weight prey cues across sensory systems when hunting in noise

(2016) D. G. E. Gomes et al.   SCIENCE

Transient potassium channels augment degeneracy in hippocampal active dendritic spectral tuning

(2016) Rahul Kumar Rathour et al.   Scientific Reports

Cognitive Aging and Time Perception: Roles of Bayesian Optimization and Degeneracy

(2016) Martine Turgeon et al.   Frontiers in Aging Neuroscience

Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex

(2016) Samuel A. Neymotin et al.   Frontiers in Pharmacology

Female mate choice for multimodal courtship and the importance of the signaling background for selection on male ornamentation

(2016) Jay A. Stafstrom et al.   Current Zoology

Hidden in plain view: degeneracy in complex systems

(2015) P.H. Mason et al.   BIOSYSTEMS

Discrete Neural Signatures of Basic Emotions

(2015) Heini Saarimäki et al.   CEREBRAL CORTEX

Analogous Synaptic Plasticity Profiles Emerge from Disparate Channel Combinations

(2015) A. Anirudhan et al.   JOURNAL OF NEUROSCIENCE

Active dendrites mediate stratified gamma-range coincidence detection in hippocampal model neurons

(2015) Anindita Das et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ion channel degeneracy enables robust and tunable neuronal firing rates

(2015) Guillaume Drion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivariate neural biomarkers of emotional states are categorically distinct

(2015) Philip A. Kragel et al.   Social Cognitive and Affective Neuroscience

A Bayesian Model of Category-Specific Emotional Brain Responses

(2015) Tor D. Wager et al.   PLoS Computational Biology

Spoken language achieves robustness and evolvability by exploiting degeneracy and neutrality

(2014) Bodo Winter   BIOESSAYS

Phase maintenance in a rhythmic motor pattern during temperature changes in vivo

(2014) Wafa Soofi et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural and genetic degeneracy underlies Caenorhabditis elegans feeding behavior

(2014) Nicholas F. Trojanowski et al.   JOURNAL OF NEUROPHYSIOLOGY

Active Dendrites Regulate Spectral Selectivity in Location-Dependent Spike Initiation Dynamics of Hippocampal Model Neurons

(2014) A. Das et al.   JOURNAL OF NEUROSCIENCE

Encoding of fear learning and memory in distributed neuronal circuits

(2014) Cyril Herry et al.   NATURE NEUROSCIENCE

Cell Types, Network Homeostasis, and Pathological Compensation from a Biologically Plausible Ion Channel Expression Model

(2014) Timothy O’Leary et al.   NEURON

Homeostasis of functional maps in active dendrites emerges in the absence of individual channelostasis

(2014) R. K. Rathour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring emotions using invasive methods: review of 60 years of human intracranial electrophysiology

(2014) Sean A. Guillory et al.   Social Cognitive and Affective Neuroscience

Evolution of Integrated Causal Structures in Animats Exposed to Environments of Increasing Complexity

(2014) Larissa Albantakis et al.   PLoS Computational Biology

Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

(2014) Stéphanie Ratté et al.   eLife

Neural Basis of the Perception and Estimation of Time

(2013) Hugo Merchant et al.   Annual Review of Neuroscience

Epigenomics and the concept of degeneracy in biological systems

(2013) R. Maleszka et al.   Briefings in Functional Genomics

Compensation for Variable Intrinsic Neuronal Excitability by Circuit-Synaptic Interactions

(2013) R. Grashow et al.   JOURNAL OF NEUROSCIENCE

Neurons within the Same Network Independently Achieve Conserved Output by Differentially Balancing Variable Conductance Magnitudes

(2013) J. L. Ransdell et al.   JOURNAL OF NEUROSCIENCE

Impact of Neuronal Properties on Network Coding: Roles of Spike Initiation Dynamics and Robust Synchrony Transfer

(2013) Stéphanie Ratté et al.   NEURON

A Calcium-Dependent Plasticity Rule for HCN Channels Maintains Activity Homeostasis and Stable Synaptic Learning

(2013) Suraj Honnuraiah et al.   PLoS One

Correlations in ion channel expression emerge from homeostatic tuning rules

(2013) T. O'Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying causal emergence shows that macro can beat micro

(2013) E. P. Hoel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Minimal Complexity of Adapting Agents Increases with Fitness

(2013) Nikhil J. Joshi et al.   PLoS Computational Biology

The Effects of Temperature on the Stability of a Neuronal Oscillator

(2013) Anatoly Rinberg et al.   PLoS Computational Biology

Floral signal complexity as a possible adaptation to environmental variability: a test using nectar-foraging bumblebees, Bombus impatiens

(2012) Rainee L. Kaczorowski et al.   ANIMAL BEHAVIOUR

Fear Processing and Social Networking in the Absence of a Functional Amygdala

(2012) Benjamin Becker et al.   BIOLOGICAL PSYCHIATRY

Mirroring Fear in the Absence of a Functional Amygdala

(2012) Yoan Mihov et al.   BIOLOGICAL PSYCHIATRY

Robustness of a Rhythmic Circuit to Short- and Long-Term Temperature Changes

(2012) L. S. Tang et al.   JOURNAL OF NEUROSCIENCE

Ca2+/cAMP-Sensitive Covariation of IA and IH Voltage Dependences Tunes Rebound Firing in Dopaminergic Neurons

(2012) J. Amendola et al.   JOURNAL OF NEUROSCIENCE

Ionic Current Correlations Underlie the Global Tuning of Large Numbers of Neuronal Activity Attributes

(2012) S. Zhao et al.   JOURNAL OF NEUROSCIENCE

Inactivating ion channels augment robustness of subthreshold intrinsic response dynamics to parametric variability in hippocampal model neurons

(2012) Rahul Kumar Rathour et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of Molecular Pathologies Sufficient to Cause Neuropathic Excitability in Primary Somatosensory Afferents Using Dynamical Systems Theory

(2012) Young-Ah Rho et al.   PLoS Computational Biology

A database of computational models of a half-center oscillator for analyzing how neuronal parameters influence network activity

(2011) Anca Doloc-Mihu et al.   JOURNAL OF BIOLOGICAL PHYSICS

Neuromodulation independently determines correlated channel expression and conductance levels in motor neurons of the stomatogastric ganglion

(2011) Simone Temporal et al.   JOURNAL OF NEUROPHYSIOLOGY

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Multiple models to capture the variability in biological neurons and networks

(2011) Eve Marder et al.   NATURE NEUROSCIENCE

Patterns of pain: Meta-analysis of microarray studies of pain

(2011) Michael L. LaCroix-Fralish et al.   PAIN

Variability, compensation, and modulation in neurons and circuits

(2011) E. Marder   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA-seq with agnostic splice site discovery for nervous system transcriptomics tested in chronic pain

(2010) P. Hammer et al.   GENOME RESEARCH

Applications of the principle of maximum entropy: from physics to ecology

(2010) Jayanth R Banavar et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics

(2010) Rita Zemankovics et al.   JOURNAL OF PHYSIOLOGY-LONDON

Coordinating Different Homeostatic Processes

(2010) Eve Marder et al.   NEURON

Grounding emotion in situated conceptualization

(2010) Christine D. Wilson-Mendenhall et al.   NEUROPSYCHOLOGIA

Dissociable Neural Systems for Timing: Evidence from Subjects with Basal Ganglia Lesions

(2010) H. Branch Coslett et al.   PLoS One

Degeneracy: a link between evolvability, robustness and complexity in biological systems

(2010) James M Whitacre   Theoretical Biology and Medical Modelling

Precise Temperature Compensation of Phase in a Rhythmic Motor Pattern

(2010) Lamont S. Tang et al.   PLOS BIOLOGY

Conductance Ratios and Cellular Identity

(2010) Amber E. Hudson et al.   PLoS Computational Biology

Increased frontoparietal integration after stroke and cognitive recovery

(2009) David J. Sharp et al.   ANNALS OF NEUROLOGY

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Bilateral limbic system destruction in man

(2009) Justin S. Feinstein et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

Neuroimaging Support for Discrete Neural Correlates of Basic Emotions: A Voxel-based Meta-analysis

(2009) Katherine Vytal et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

How Multiple Conductances Determine Electrophysiological Properties in a Multicompartment Model

(2009) A. L. Taylor et al.   JOURNAL OF NEUROSCIENCE

Degeneracy: A design principle for achieving robustness and evolvability

(2009) James Whitacre et al.   JOURNAL OF THEORETICAL BIOLOGY

Correlations in Ion Channel mRNA in Rhythmically Active Neurons

(2009) Anne-Elise Tobin et al.   PLoS One

The free-energy principle: a rough guide to the brain?

(2009) Karl Friston   TRENDS IN COGNITIVE SCIENCES

Channel Density Distributions Explain Spiking Variability in the Globus Pallidus: A Combined Physiology and Computer Simulation Database Approach

(2008) C. Gunay et al.   JOURNAL OF NEUROSCIENCE

Keep Your Options Open: An Information-Based Driving Principle for Sensorimotor Systems

(2008) Alexander S. Klyubin et al.   PLoS One

Biophysical Basis for Three Distinct Dynamical Mechanisms of Action Potential Initiation

(2008) Steven A. Prescott et al.   PLoS Computational Biology

Gonadotropin-Releasing Hormone Neuron Requirements for Puberty, Ovulation, and Fertility

(2007) Allan E. Herbison et al.   ENDOCRINOLOGY