Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis

NF ‐E2–Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus

(2020) Shuhong Han et al.   Arthritis & Rheumatology

Transfection Efficiency Evaluation and Endocytosis Exploration of Different Polymer Condensed Agents

(2019) Jianhua Wang et al.   DNA AND CELL BIOLOGY

Mechanisms of Carrier Formation during Clathrin-Independent Endocytosis

(2018) Antonio P.A. Ferreira et al.   TRENDS IN CELL BIOLOGY

Neutrophil extracellular traps promote macrophage pyroptosis in sepsis

(2018) Linsong Chen et al.   Cell Death & Disease

Update on Lupus Nephritis

(2016) Salem Almaani et al.   Clinical Journal of the American Society of Nephrology

Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages

(2016) Hui Zhang et al.   Journal of Translational Medicine

Delivery methods to increase cellular uptake and immunogenicity of DNA vaccines

(2016) S.H.T. Jorritsma et al.   VACCINE

Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE

(2016) Aparna Mahajan et al.   Frontiers in Immunology

Imaging and spectroscopic comparison of multi-step methods to form DNA arrays based on the biotin–streptavidin system

(2015) Katarzyna Gajos et al.   ANALYST

Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis

(2015) Xiaoyun Li et al.   MOLECULAR IMMUNOLOGY

Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging

(2014) Ramsey N. Majzoub et al.   BIOMATERIALS

Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

(2014) J Xu et al.   CELL DEATH AND DIFFERENTIATION

TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant

(2014) Rebecca Saenz et al.   Journal of Translational Medicine

Concerted Spatio-Temporal Dynamics of Imported DNA and ComE DNA Uptake Protein during Gonococcal Transformation

(2014) Heike Gangel et al.   PLoS Pathogens

Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake

(2012) Yusong Zhang et al.   BIOCHEMICAL PHARMACOLOGY

The DNA Binding and Bending Activities of Truncated Tail-less HMGB1 protein are Differentially Affected by Lys-2 and Lys-81 Residues and Their Acetylation

(2012) Ivan Elenkov et al.   International Journal of Biological Sciences

High-mobility group box 1 represents a potential marker of disease activity and novel therapeutic target in systemic lupus erythematosus

(2011) V. Urbonaviciute et al.   JOURNAL OF INTERNAL MEDICINE

Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization

(2010) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

Expression of High Mobility Group Box Chromosomal Protein 1 and Its Modulating Effects on Downstream Cytokines in Systemic Lupus Erythematosus

(2010) J. LI et al.   JOURNAL OF RHEUMATOLOGY

Rac-Mediated Macropinocytosis Is a Critical Route for Naked Plasmid DNA Transfer in Mice

(2009) Shintaro Fumoto et al.   MOLECULAR PHARMACEUTICS

TLR9 as a key receptor for the recognition of DNA☆

(2008) Y KUMAGAI et al.   ADVANCED DRUG DELIVERY REVIEWS

Pathogenic anti-DNA antibodies modulate gene expression in mesangial cells: Involvement of HMGB1 in anti-DNA antibody-induced renal injury

(2008) Xiaoping Qing et al.   IMMUNOLOGY LETTERS

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells

(2008) Selina Khan et al.   MOLECULAR IMMUNOLOGY