Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis

Published 2015 View Full Article

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Title
Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis
Authors
Keywords
HMGB1, Activated lymphocyte-derived DNA (ALD-DNA), Macrophage activation, SLE
Journal
MOLECULAR IMMUNOLOGY
Volume 65, Issue 1, Pages 177-188
Publisher
Elsevier BV
Online
2015-02-06
DOI
10.1016/j.molimm.2015.01.023

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