Mitochondrial-derived peptides and exercise

A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c

(2021) Hirofumi Zempo et al.   Aging-US

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

(2021) Joseph C. Reynolds et al.   Nature Communications

Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism

(2021) Gil Myoung Kang et al.   Cell Metabolism

Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers

(2021) Mikael Flockhart et al.   Cell Metabolism

Effect of aerobic and resistance exercise on the mitochondrial peptide MOTS-c in Hispanic and Non-Hispanic White breast cancer survivors

(2021) Christina M. Dieli-Conwright et al.   Scientific Reports

Plasma mitochondrial derived peptides MOTS-c and SHLP2 positively associate with android and liver fat in people without diabetes

(2021) Ivana R. Sequeira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition

(2020) Randall F. D’Souza et al.   Aging-US

High-intensity interval exercise increases humanin, a mitochondrial encoded peptide, in the plasma and muscle of men

(2020) Jonathan S. T. Woodhead et al.   JOURNAL OF APPLIED PHYSIOLOGY

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing

(2020) Beverly Y. Mok et al.   NATURE

Adiponectin treatment improves insulin resistance in mice by regulating the expression of the mitochondrial-derived peptide MOTS-c and its response to exercise via APPL1–SIRT1–PGC-1α

(2020) Qi Guo et al.   DIABETOLOGIA

Lipids and insulin regulate mitochondrial‐derived peptide (MOTS‐c) in PCOS and healthy subjects

(2019) Manjunath Ramanjaneya et al.   CLINICAL ENDOCRINOLOGY

Mitochondrial-Derived Peptide MOTS-c Increases Adipose Thermogenic Activation to Promote Cold Adaptation

(2019) Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Maximizing Cellular Adaptation to Endurance Exercise in Skeletal Muscle

(2018) John A. Hawley et al.   Cell Metabolism

The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

(2018) Kyung Hwa Kim et al.   Cell Metabolism

Exercise-Induced Changes in Visceral Adipose Tissue Mass Are Regulated by IL-6 Signaling: A Randomized Controlled Trial

(2018) Anne-Sophie Wedell-Neergaard et al.   Cell Metabolism

Development of a mass spectrometry-based detection method for the mitochondrion-derived peptide MOTS-c in plasma samples for doping control purposes

(2018) A. Knoop et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mitochondrially derived peptides as novel regulators of metabolism

(2017) Su-Jeong Kim et al.   JOURNAL OF PHYSIOLOGY-LONDON

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

(2016) Laura J. Cobb et al.   Aging-US

Mitohormesis in exercise training

(2016) Troy L. Merry et al.   FREE RADICAL BIOLOGY AND MEDICINE

MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism

(2016) Changhan Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nuclear factor erythroid-derived 2-like 2 (NFE2L2, Nrf2) mediates exercise-induced mitochondrial biogenesis and the anti-oxidant response in mice

(2016) Troy L. Merry et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nrf2 mediates redox adaptations to exercise

(2016) Aaron J. Done et al.   Redox Biology

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

(2015) Svenia Schnyder et al.   BONE

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

(2015) Changhan Lee et al.   Cell Metabolism

Integrative Biology of Exercise

(2014) John A. Hawley et al.   CELL

Pharmacokinetics and Tissue Distribution of Humanin and Its Analogues in Male Rodents

(2013) Yung-Ping Chin et al.   ENDOCRINOLOGY

Humanin: a harbinger of mitochondrial-derived peptides?

(2013) Changhan Lee et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The emerging role of the mitochondrial-derived peptide humanin in stress resistance

(2012) Kelvin Yen et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Interaction between SNPs in the NRF2 gene and elite endurance performance

(2009) Nir Eynon et al.   PHYSIOLOGICAL GENOMICS