Trichostatin A Relieves Growth Suppression and Restores Histone Acetylation at Specific Sites in a FUS ALS/FTD Yeast Model

Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway

(2021) Yen-Chen Lin et al.   NATURE NEUROSCIENCE

Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models

(2020) Rachel Kuta et al.   CELL STRESS & CHAPERONES

HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo

(2020) Simona Sanna et al.   Cell Death & Disease

Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation

(2019) Joy M Cote et al.   NUCLEIC ACIDS RESEARCH

Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model

(2019) Elisabeth Rossaert et al.   Acta Neuropathologica Communications

Epigenetics in amyotrophic lateral sclerosis: a role for histone post-translational modifications in neurodegenerative disease

(2018) Seth A. Bennett et al.   Translational Research

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

(2016) Yulei Shang et al.   BRAIN RESEARCH

Saccharomyces cerevisiae TORC1 Controls Histone Acetylation by Signaling Through the Sit4/PP6 Phosphatase to Regulate Sirtuin Deacetylase Nuclear Accumulation

(2016) Jason J. Workman et al.   GENETICS

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

Saccharomyces cerevisiae TORC1 Controls Histone Acetylation by Signaling Through the Sit4/PP6 Phosphatase to Regulate Sirtuin Deacetylase Nuclear Accumulation

(2016) Jason J. Workman et al.   GENETICS

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

(2016) Matthew Nolan et al.   Acta Neuropathologica Communications

Basic concepts of epigenetics

(2012) Elizabeth A. Mazzio et al.   Epigenetics

Differentiation and upregulation of heat shock protein 70 induced by a subset of histone deacetylase inhibitors in mouse and human embryonic stem cells

(2011) Jeong-A Park et al.   BMB Reports

Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis

(2011) Young-Eun Yoo et al.   EXPERIMENTAL NEUROLOGY

Hst3 and Hst4 histone deacetylases regulate replicative lifespan by preventing genome instability in Saccharomyces cerevisiae

(2011) Mayumi Hachinohe et al.   GENES TO CELLS

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

(2011) Zhihui Sun et al.   PLOS BIOLOGY

A histone deacetylase-dependent screen in yeast

(2010) Sujith V.W. Weerasinghe et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109

(2008) J. Fillingham et al.   MOLECULAR AND CELLULAR BIOLOGY

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

(2008) B. S. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA