Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics
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Title
Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics
Authors
Keywords
Doxorubicin-induced cardiotoxicity, Melatonin, Metformin, Heart, Mitochondria
Journal
BIOCHEMICAL PHARMACOLOGY
Volume 192, Issue -, Pages 114743
Publisher
Elsevier BV
Online
2021-08-26
DOI
10.1016/j.bcp.2021.114743
References
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Note: Only part of the references are listed.- Effects of Melatonin and Adrenomedullin in Reducing the Cardiotoxic Effects of Doxorubicin in Rats
- (2021) Gulcin Durdagi et al. Cardiovascular Toxicology
- Non-invasive transcutaneous vagal nerve stimulation improves myocardial performance in doxorubicin-induced cardiotoxicity
- (2021) Yanqiu Lai et al. CARDIOVASCULAR RESEARCH
- Enhanced antitumor activity of doxorubicin by naringenin and metformin in breast carcinoma: an experimental study
- (2021) Bharat Pateliya et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Combination of Metformin, Sodium Oxamate and Doxorubicin Induces Apoptosis and Autophagy in Colorectal Cancer Cells via Downregulation HIF-1α
- (2021) Jossimar Coronel-Hernández et al. Frontiers in Oncology
- Melatonin attenuates doxorubicin‐induced cardiotoxicity through preservation of YAP expression
- (2020) Hai‐ru Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia‐reperfusion injury by improving mitochondrial quality control: Role of SIRT6
- (2020) Li‐Ming Yu et al. JOURNAL OF PINEAL RESEARCH
- Cardioprotective effect of grape polyphenol extract against doxorubicin induced cardiotoxicity
- (2020) Shynggys Sergazy et al. Scientific Reports
- Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage
- (2020) Goowon Yang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Combined low-dose testosterone and vildagliptin confers cardioprotection in castrated obese rats
- (2019) Apiwan Arinno et al. JOURNAL OF ENDOCRINOLOGY
- Resveratrol attenuates doxorubicin-induced cardiotoxicity in rats by up-regulation of vascular endothelial growth factor B
- (2019) Wencong Tian et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity
- (2019) Michele Russo et al. EUROPEAN JOURNAL OF HEART FAILURE
- Doxorubicin treatments induce significant changes on the cardiac autonomic nervous system in childhood acute lymphoblastic leukemia long-term survivors
- (2019) Maxime Caru et al. Clinical Research in Cardiology
- Mechanisms of action of metformin with special reference to cardiovascular protection
- (2019) Alexey V. Zilov et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Vagus nerve stimulation exerts cardioprotection against myocardial ischemia/reperfusion injury predominantly through its efferent vagal fibers
- (2018) Watthana Nuntaphum et al. BASIC RESEARCH IN CARDIOLOGY
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Testosterone Deprivation Aggravates Left-Ventricular Dysfunction in Male Obese Insulin-Resistant Rats via Impairing Cardiac Mitochondrial Function and Dynamics Proteins
- (2018) Nattayaporn Apaiajai et al. GERONTOLOGY
- The Cardioprotective Effect of Metformin in Doxorubicin-Induced Cardiotoxicity: The Role of Autophagy
- (2018) Rita Zilinyi et al. MOLECULES
- Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?
- (2018) Zukiswa Jiki et al. Frontiers in Physiology
- Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction
- (2018) Yuan Liu et al. Redox Biology
- AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis
- (2018) Dong Liu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin attenuates myocardial ischemia reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK-OPA1 signaling pathways
- (2018) Ying Zhang et al. JOURNAL OF PINEAL RESEARCH
- Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer
- (2017) Ke Chen et al. Molecular Cancer
- Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models
- (2017) Ying Li et al. Oncotarget
- Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
- (2017) Vinodkumar B. Pillai et al. Oncotarget
- Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells
- (2017) Wei Xie et al. MEDICAL SCIENCE MONITOR
- Cardiac autonomic modulation induced by doxorubicin in a rodent model of colorectal cancer and the influence of fullerenol pretreatment
- (2017) Nejka Potočnik et al. PLoS One
- Doxorubicin-Induced Systemic Inflammation Is Driven by Upregulation of Toll-Like Receptor TLR4 and Endotoxin Leakage
- (2016) Lintao Wang et al. CANCER RESEARCH
- Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE
- (2016) Dan L. Li et al. CIRCULATION
- Mitochondrial Dynamics and Metabolic Regulation
- (2016) Timothy Wai et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARα-cyclophilin D interaction in cardiomyocytes
- (2015) Giselle Barreto-Torres et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Thymol and Carvacrol Prevent Doxorubicin-Induced Cardiotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats
- (2015) El-Sayed M. El-Sayed et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes
- (2015) Kyle G. Cheung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress
- (2015) Inês Marques-Aleixo et al. MITOCHONDRION
- Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment
- (2015) Qian Guo et al. Oxidative Medicine and Cellular Longevity
- Heart rate dynamics in doxorubicin-induced cardiomyopathy
- (2015) T Lončar-Turukalo et al. PHYSIOLOGICAL MEASUREMENT
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- (2014) Dmitry B. Zorov et al. PHYSIOLOGICAL REVIEWS
- Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats
- (2013) Nattayaporn Apaijai et al. BRITISH JOURNAL OF PHARMACOLOGY
- Protective effect of melatonin against Adriamycin-induced cardiotoxicity
- (2013) YAN ZHANG et al. Experimental and Therapeutic Medicine
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- (2012) Abdelkader E. Ashour et al. Oxidative Medicine and Cellular Longevity
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- (2012) Yonggang Ma et al. PLoS One
- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
- (2012) W-Y Shi et al. Cell Death & Disease
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- (2010) I. Brana et al. ANNALS OF ONCOLOGY
- Global Patterns of Cancer Incidence and Mortality Rates and Trends
- (2010) A. Jemal et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Effects of a high-fat diet on energy metabolism and ROS production in rat liver
- (2010) Guillaume Vial et al. JOURNAL OF HEPATOLOGY
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- (2010) Danielle Glick et al. JOURNAL OF PATHOLOGY
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- (2009) Elizabeth D. Brookins Danz et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2009) H. Lemieux et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- ACE inhibition and protection from doxorubicin-induced cardiotoxicity in the rat
- (2009) Giuseppe Sacco et al. VASCULAR PHARMACOLOGY
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