Chicago sky blue 6B (CSB6B), an allosteric inhibitor of macrophage migration inhibitory factor (MIF), suppresses osteoclastogenesis and promotes osteogenesis through the inhibition of the NF-κB signaling pathway

Elevated Expression of Macrophage Migration Inhibitory Factor Promotes Inflammatory Bone Resorption Induced in a Mouse Model of Periradicular Periodontitis

(2019) Mohammed Howait et al.   JOURNAL OF IMMUNOLOGY

Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway

(2019) Lin Zheng et al.   FASEB JOURNAL

Rare adverse effects of bisphosphonate therapy

(2019) Zubair Ilyas et al.   Current Opinion in Endocrinology Diabetes and Obesity

Macrophage Migration Inhibitory Factor Induces Inflammation and Predicts Spinal Progression in Ankylosing Spondylitis

(2017) Vidya Ranganathan et al.   Arthritis & Rheumatology

Macrophage Migration Inhibitory Factor (MIF) Supports Homing of Osteoclast Precursors to Peripheral Osteolytic Lesions

(2016) Alexandru Movila et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeting MIF in Cancer: Therapeutic Strategies, Current Developments, and Future Opportunities

(2016) Ciaran O'Reilly et al.   MEDICINAL RESEARCH REVIEWS

MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia

(2016) Yuan Yao et al.   Stem Cell Reports

Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis

(2015) Ran Gu et al.   CYTOKINE

MIF, a potential therapeutic target for rheumatoid arthritis?

(2014) Zhaolin Chen et al.   RHEUMATOLOGY INTERNATIONAL

NF-κB RelB Negatively Regulates Osteoblast Differentiation and Bone Formation

(2013) Zhenqiang Yao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Macrophage-derived, macrophage migration inhibitory factor (MIF) is necessary to induce disease in the K/BxN serum-induced model of arthritis

(2013) Anjana Singh et al.   RHEUMATOLOGY INTERNATIONAL

A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)

(2012) Fengwei Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

(2012) Ramona Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

Bone remodelling at a glance

(2011) J. C. Crockett et al.   JOURNAL OF CELL SCIENCE

MIF induces osteoclast differentiation and contributes to progression of periodontal disease in mice

(2011) Mila Fernandes Moreira Madeira et al.   MICROBES AND INFECTION

Macrophage migration inhibitory factor enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis

(2011) Hae-Rim Kim et al.   ARTHRITIS RESEARCH & THERAPY

Functions of nuclear factor κB in bone

(2010) Brendan F. Boyce et al.   Annals of the New York Academy of Sciences

Suppression of NF-κB Increases Bone Formation and Ameliorates Osteopenia in Ovariectomized Mice

(2010) Neil Alles et al.   ENDOCRINOLOGY

Impaired fracture healing in macrophage migration inhibitory factor-deficient mice

(2010) T. Kobayashi et al.   OSTEOPOROSIS INTERNATIONAL

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Identification of NFAT binding sites that mediate stimulation of cathepsin K promoter activity by RANK ligand

(2009) Wayne Balkan et al.   GENE

Tumor Necrosis Factor α Represses Bone Morphogenetic Protein (BMP) Signaling by Interfering with the DNA Binding of Smads through the Activation of NF-κB

(2009) Masato Yamazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL