The genetics of osteoporosis

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture

(2013) J. Brent Richards   ANNALS OF INTERNAL MEDICINE

Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus

(2013) Ling Oei et al.   BONE

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

(2013) Karen A. Hunt et al.   NATURE

Next-generation sequencing: a frameshift in skeletal dysplasia gene discovery

(2013) S. Lazarus et al.   OSTEOPOROSIS INTERNATIONAL

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Studies of Skeletal Phenotypes: What We Have Learned and Where We Are Headed

(2012) Yi-Hsiang Hsu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Genetics of osteoporosis from genome-wide association studies: advances and challenges

(2012) J. Brent Richards et al.   NATURE REVIEWS GENETICS

The Predictive Capacity of Personal Genome Sequencing

(2012) N. J. Roberts et al.   Science Translational Medicine

Nosology and classification of genetic skeletal disorders: 2010 revision

(2011) Matthew L. Warman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Update on Wnt signaling in bone cell biology and bone disease

(2011) David G. Monroe et al.   GENE

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

(2011) Naomi R. Wray et al.   PLOS BIOLOGY

Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk

(2011) Emma L. Duncan et al.   PLoS Genetics

Mapping genes for osteoporosis—Old dogs and new tricks

(2010) Emma L. Duncan et al.   BONE

Family history of osteoporosis and bone mineral density at the axial skeleton: The rancho bernardo study

(2010) Sharon B. Soroko et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genetic Determinants of Bone Density and Fracture Risk—State of the Art and Future Directions

(2010) Emma L. Duncan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study

(2008) JB Richards et al.   LANCET

Multiple Genetic Loci for Bone Mineral Density and Fractures

(2008) Unnur Styrkarsdottir et al.   NEW ENGLAND JOURNAL OF MEDICINE