Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH

Reactive Oxygen Species Responsive Theranostic Nanoplatform for Two-Photon Aggregation-Induced Emission Imaging and Therapy of Acute and Chronic Inflammation

(2020) Boxuan Ma et al.   ACS Nano

A review of hepatic nanotoxicology – summation of recent findings and considerations for the next generation of study designs

(2020) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Distinguishing NASH Histological Severity Using a Multiplatform Metabolomics Approach

(2020) George N. Ioannou et al.   Metabolites

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

(2020) Olivier Govaere et al.   Science Translational Medicine

Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

(2019) Ali Kermanizadeh et al.   Particle and Fibre Toxicology

Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis

(2019) Olga Khomich et al.   Cells

Models of Drug Induced Liver Injury (DILI) – Current Issues and Future Perspectives

(2018) Lucija Kuna et al.   CURRENT DRUG METABOLISM

Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice

(2018) Justyna Modrzynska et al.   Particle and Fibre Toxicology

Intestinal injury alters tissue distribution and toxicity of ZnO nanoparticles in mice

(2018) Li-Jing Du et al.   TOXICOLOGY LETTERS

Nanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape

(2018) Ali Kermanizadeh et al.   International Journal of Nanomedicine

Human hepatic stellate cell isolation and characterization

(2017) Linshan Shang et al.   JOURNAL OF GASTROENTEROLOGY

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Hepatic Hazard Assessment of Silver Nanoparticle Exposure in Healthy and Chronically Alcohol Fed Mice

(2017) Ali Kermanizadeh et al.   TOXICOLOGICAL SCIENCES

Nanomaterial translocation–the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs–a review

(2015) Ali Kermanizadeh et al.   CRITICAL REVIEWS IN TOXICOLOGY

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Sterile inflammation in acute liver injury: myth or mystery?

(2015) Benjamin L Woolbright et al.   Expert Review of Gastroenterology & Hepatology

Nonalcoholic Fatty Liver Disease is Underrecognized in the Primary Care Setting

(2014) Pierre Blais et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of Kupffer cells in the hepatic response to silver nanoparticles

(2013) Ali Kermanizadeh et al.   Nanotoxicology

Biopersistence of silver nanoparticles in tissues from Sprague–Dawley rats

(2013) Ji Lee et al.   Particle and Fibre Toxicology

Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans

(2013) Michiko Itoh et al.   PLoS One

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Investigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applications

(2012) Helinor Johnston et al.   JOURNAL OF CONTROLLED RELEASE

In vitroassessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers

(2012) Ali Kermanizadeh et al.   Nanotoxicology

Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection

(2010) Jens Lipka et al.   BIOMATERIALS

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

(2009) Suresh K. Balasubramanian et al.   BIOMATERIALS