Molecular mechanism involved in epithelial to mesenchymal transition

TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1

(2020) Jie Su et al.   NATURE

miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4

(2020) Yujing Fan et al.   Molecular Medicine Reports

Nicotine promotes tumor progression and epithelial-mesenchymal transition by regulating the miR-155-5p/NDFIP1 axis in pancreatic ductal adenocarcinoma

(2020) Qiwen Ben et al.   PANCREATOLOGY

miR‐15b enhances the proliferation and migration of lung adenocarcinoma by targeting BCL2

(2020) Jun Wang et al.   Thoracic Cancer

MiR‐194‐5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk

(2019) Hong Liu et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

MiR-27b suppresses epithelial–mesenchymal transition and chemoresistance in lung cancer by targeting Snail1

(2019) Jun Zhang et al.   LIFE SCIENCES

miR-194 suppresses epithelial-mesenchymal transition of retinal pigment epithelial cells by directly targeting ZEB1

(2019) Lian Cui et al.   Annals of Translational Medicine

Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation

(2018) Hua Chen et al.   PHYTOMEDICINE

Revealing the brain's molecular architecture

(2018)   SCIENCE

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

New insights into the role of EMT in tumor immune escape

(2017) Stéphane Terry et al.   Molecular Oncology

MicroRNA-194 represses glioma cell epithelial-to-mesenchymal transition by targeting Bmi1

(2017) Xi Zhang et al.   ONCOLOGY REPORTS

E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness

(2017) Marina Rosso et al.   PLoS One

Down-regulation of miR-23a inhibits high glucose-induced EMT and renal fibrogenesis by up-regulation of SnoN

(2017) Haiping Xu et al.   Human Cell

Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

(2017) Wen-Sheng Wu et al.   Scientific Reports

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2

(2016) Rajdeep Das et al.   CANCER RESEARCH

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways

(2016) Xin Kong et al.   Oncotarget

miR-15b Inhibits the Progression of Glioblastoma Cells Through Targeting Insulin-like Growth Factor Receptor 1

(2016) Jian Wang et al.   Hormones & Cancer

miR-27a-3p suppresses tumor metastasis and VM by down-regulating VE-cadherin expression and inhibiting EMT: an essential role for Twist-1 in HCC

(2016) Nan Zhao et al.   Scientific Reports

ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

(2015) Peijing Zhang et al.   CELL CYCLE

Unraveling the TWIST between EMT and Cancer Stemness

(2015) Hae-Yun Jung et al.   Cell Stem Cell

miR-15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer

(2015) WEN-LONG ZHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Snail modulates the assembly of fibronectin via α5 integrin for myocardial migration in zebrafish embryos

(2014) Liangjun Qiao et al.   Scientific Reports

ERG Is a Critical Regulator of Wnt/LEF1 Signaling in Prostate Cancer

(2013) L. Wu et al.   CANCER RESEARCH

Wnt signaling in adult intestinal stem cells and cancer

(2013) Michaela Krausova et al.   CELLULAR SIGNALLING

Does the cranial mesenchyme contribute to neural fold elevation during neurulation?

(2012) Irene E. Zohn et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition

(2012) Jason C. Kovacic et al.   CIRCULATION

miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells

(2012) Jipeng Li et al.   FEBS LETTERS

MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells

(2012) MENGRU CAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

(2012) Dahu Chen et al.   NATURE MEDICINE

miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1

(2011) Jingcheng Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities

(2011) Fen Yang et al.   EMBO JOURNAL

The role of tristetraprolin in cancer and inflammation

(2011) Sandhya Sanduja   Frontiers in Bioscience-Landmark

MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer

(2011) Regalla Kumarswamy et al.   INTERNATIONAL JOURNAL OF CANCER

miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT

(2011) X Xiang et al.   ONCOGENE

MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1

(2011) L Sun et al.   ONCOGENE

miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition

(2011) Ziping Zhang et al.   Cancer Genetics

A MicroRNA Targeting Dicer for Metastasis Control

(2010) Graziano Martello et al.   CELL

MicroRNA-204/211 alters epithelial physiology

(2010) Fei E. Wang et al.   FASEB JOURNAL

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

(2010) Li Ma et al.   NATURE CELL BIOLOGY

miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers

(2010) G Vetter et al.   ONCOGENE

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

Epithelial–mesenchymal transition in ovarian cancer

(2009) Daniele Vergara et al.   CANCER LETTERS

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis

(2009) Christoph A Gebeshuber et al.   EMBO REPORTS

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/ -Catenin Signaling Pathway

(2009) O. Saydam et al.   MOLECULAR AND CELLULAR BIOLOGY

Interplay of Cadherin-Mediated Cell Adhesion and Canonical Wnt Signaling

(2009) J. Heuberger et al.   Cold Spring Harbor Perspectives in Biology

Deregulating EMT and Senescence: Double Impact by a Single Twist

(2008) Marjon A. Smit et al.   CANCER CELL

The Fbxw7/hCdc4 tumor suppressor in human cancer

(2008) YingMeei Tan et al.   CANCER LETTERS

Rb Depletion Results in Deregulation of E-Cadherin and Induction of Cellular Phenotypic Changes that Are Characteristic of the Epithelial-to-Mesenchymal Transition

(2008) Y. Arima et al.   CANCER RESEARCH

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of the ZEB family of transcription factors in development and disease

(2008) C. Vandewalle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

(2008) Sylvie Thuault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

Erk5 Controls Slug Expression and Keratinocyte Activation during Wound Healing

(2008) Valerie Arnoux et al.   MOLECULAR BIOLOGY OF THE CELL

Twisted epithelial–mesenchymal transition blocks senescence

(2008) Robert A. Weinberg   NATURE CELL BIOLOGY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

(2008) Yukiko Nakaya et al.   NATURE CELL BIOLOGY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

(2008) E L Whiteman et al.   ONCOGENE

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA