Histone methyltransferase SETDB1 inhibits TGF-β-induced epithelial–mesenchymal transition in pulmonary fibrosis by regulating SNAI1 expression and the ferroptosis signaling pathway

TGF-β-induced α-SMA expression is mediated by C/EBPβ acetylation in human alveolar epithelial cells

(2021) Hui Ding et al.   MOLECULAR MEDICINE

SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States

(2020) Kaixin Wu et al.   Cell Reports

Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer

(2020) Jaewang Lee et al.   Redox Biology

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms

(2020) Lulu Sun et al.   DNA AND CELL BIOLOGY

Redox Imbalance in Idiopathic Pulmonary Fibrosis: A Role for Oxidant Cross-Talk Between NOX Enzymes and Mitochondria

(2019) Carmen Veith et al.   ANTIOXIDANTS & REDOX SIGNALING

Lipid Peroxidation and GPX4 Inhibition Are Common Causes for Myofibroblast Differentiation and Ferroptosis

(2019) Yue Gong et al.   DNA AND CELL BIOLOGY

Schisandrin B inhibits TGF-β1-induced epithelial-mesenchymal transition in human A549 cells through epigenetic silencing of ZEB1

(2019) Wenyue Zhuang et al.   EXPERIMENTAL LUNG RESEARCH

Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling

(2019) Jiao Wu et al.   NATURE

Acetaminophen sensitizing erastin‐induced ferroptosis via modulation of Nrf2/heme oxygenase‐1 signaling pathway in non‐small‐cell lung cancer

(2019) Chengcheng Gai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis

(2019) Kazuya Tsubouchi et al.   JOURNAL OF IMMUNOLOGY

Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma

(2018) Yuqin Zhang et al.   BMC CANCER

A Chinese Herbal Formula Ameliorates Pulmonary Fibrosis by Inhibiting Oxidative Stress via Upregulating Nrf2

(2018) Yunping Bai et al.   Frontiers in Pharmacology

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse

(2016) Jeesun Kim et al.   PLoS Genetics

Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosisin vivo

(2015) Chiharu Ota et al.   EXPERIMENTAL LUNG RESEARCH

Regulation of Gene Expression by Sodium Valproate in Epithelial-to-Mesenchymal Transition

(2015) Shuhei Noguchi et al.   LUNG

Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis

(2015) Rui-Ming Liu et al.   Redox Biology

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition

(2013) Alba Millanes-Romero et al.   MOLECULAR CELL

The epigenetics of epithelial-mesenchymal plasticity in cancer

(2013) Wai Leong Tam et al.   NATURE MEDICINE

Oxidative stress and pulmonary fibrosis

(2012) Paul Cheresh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Transforming growth factor β suppresses glutamate–cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model

(2012) Rui-Ming Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism

(2012) Marta R. Gorowiec et al.   FREE RADICAL BIOLOGY AND MEDICINE

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

(2012) Chenfang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

(2011) Oliver G McDonald et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dual role of TGF-β1 on Fas-induced apoptosis in lung epithelial cells

(2011) Li Bai et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Ferritin Heavy Chain–Mediated Iron Homeostasis and Subsequent Increased Reactive Oxygen Species Production Are Essential for Epithelial-Mesenchymal Transition

(2009) Ke-Hua Zhang et al.   CANCER RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Early and Late Changes of MMP-2 and MMP-9 in Bleomycin-Induced Pulmonary Fibrosis

(2009) Ji Young Kim et al.   YONSEI MEDICAL JOURNAL

Requirement of HDAC6 for Transforming Growth Factor-β1-induced Epithelial-Mesenchymal Transition

(2008) Bin Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY