Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis

ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation

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Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol‐associated liver disease

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Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling

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Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis

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(2019) Viktor Wixler   FASEB JOURNAL

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblastsin Liver Fibrosis

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Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

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P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

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Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2

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The role of 3D-MRE in the diagnosis of NASH in obese patients undergoing bariatric surgery

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Measured pulmonary arterial tissue stiffness is highly sensitive to AFM indenter dimensions

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Distinguishing between Hepatic Inflammation and Fibrosis with MR Elastography

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Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha

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The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice

(2016) Jessica L. Maiers et al.   HEPATOLOGY

Loss of the LIM-only protein Fhl2 impairs inflammatory reaction and scar formation after cardiac ischemia leading to better hemodynamic performance

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Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

(2016) Naotaka Nakazawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

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Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury

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Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease

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Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

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Micro-Mechanical Characterization of Lung Tissue Using Atomic Force Microscopy

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

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Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS