Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome

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TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

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The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

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Integration and reanalysis of transcriptomics and methylomics data derived from blood and testis tissue of men with 47, XXY Klinefelter syndrome indicates the primary involvement of Sertoli cells in the testicular pathogenesis

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Characterization of the stem cell niche components within the seminiferous tubules in testicular biopsies of Klinefelter patients

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Testicular immune cells and vasculature in Klinefelter syndrome from childhood up to adulthood

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Unified single-cell analysis of testis gene regulation and pathology in five mouse strains

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High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting

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Leydig cells: formation, function, and regulation†

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Klinefelter syndrome: more than hypogonadism

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Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells

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Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence

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The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids

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IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators

(2018) Xinh-Xinh Nguyen et al.   Frontiers in Endocrinology

Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation

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Landscape of X chromosome inactivation across human tissues

(2017) Taru Tukiainen et al.   NATURE

Reversed graph embedding resolves complex single-cell trajectories

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Testis Transcriptome Modulation in Klinefelter Patients with Hypospermatogenesis

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WFIKKN1 and WFIKKN2: “Companion” proteins regulating TGFB activity

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Female mice lacking Xist RNA show partial dosage compensation and survive to term

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Tensor decomposition for multiple-tissue gene expression experiments

(2016) Victoria Hore et al.   NATURE GENETICS

Spermatogenesis: The Commitment to Meiosis

(2016) Michael D. Griswold   PHYSIOLOGICAL REVIEWS

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

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Deregulation of sertoli and leydig cells function in patients with klinefelter syndrome as evidenced by testis transcriptome analysis

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Reprogramming of Sertoli cells to fetal-like Leydig cells byWt1ablation

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Diagnosis and classification of Goodpasture's disease (anti-GBM)

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Therapy of endocrine disease: Testicular function and fertility in men with Klinefelter syndrome: a review

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Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience

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The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair

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DMRT1 prevents female reprogramming in the postnatal mammalian testis

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Adrenomedullin in the Rat Testis. II: Its Production, Actions on Inhibin Secretion, Regulation by Follicle-Stimulating Hormone, and Its Interaction with Endothelin 1 in the Sertoli Cell1

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