Effects of Crocin on CCL2/CCR2 Inflammatory Pathway in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats

Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats

(2020) Zhouxin Ren et al.   PHARMACEUTICAL BIOLOGY

Crocin: a protective natural antioxidant against pulmonary fibrosis induced by bleomycin

(2020) Mehrnaz Mehrabani et al.   Pharmacological Reports

Leukocyte-Dependent Regulation of Cardiac Fibrosis

(2020) Ama Dedo Okyere et al.   Frontiers in Physiology

Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure

(2020) Anis Hanna et al.   CARDIOVASCULAR DRUGS AND THERAPY

Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

(2019) Min Zhang et al.   Frontiers in Pharmacology

Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension

(2019) Hannes Hudalla et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

CCR2/CCR5-Mediated Macrophage-Smooth Muscle Cell Crosstalk in Pulmonary Hypertension

(2019) Shariq Abid et al.   EUROPEAN RESPIRATORY JOURNAL

Involvement of multiple transcription factors in regulation of IL-β-induced MCP-1 expression in alveolar type II epithelial cells

(2019) Chunguang Yan et al.   MOLECULAR IMMUNOLOGY

Effects of inorganic nitrate in a rat model of monocrotaline‐induced pulmonary arterial hypertension

(2019) Eva Malikova et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats

(2019) Chao-Yuan Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis

(2019) Marwa S. Zaghloul et al.   LIFE SCIENCES

Pulmonary hypertension: Pathophysiology beyond the lung

(2019) Aline C. Oliveira et al.   PHARMACOLOGICAL RESEARCH

Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway

(2018) Juan Ji et al.   AGING CELL

Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes

(2018) Jonathan Florentin et al.   JOURNAL OF IMMUNOLOGY

Betaine Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibiting Inflammatory Response

(2018) Jia-mei Yang et al.   MOLECULES

Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting vascular remodeling in rats

(2018) Ruizan Shi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9

(2018) Véronique Schenten et al.   Frontiers in Immunology

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Saffron against Components of Metabolic Syndrome: Current Status and Prospective

(2017) Mojtaba Shafiee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Osthole attenuates pulmonary arterial hypertension in monocrotaline-treated rats

(2017) Yeli Li et al.   Molecular Medicine Reports

PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor

(2017) Yang Bai et al.   Oncotarget

Efficacy of 1, 5, and 20 mg oral sildenafil in the treatment of adults with pulmonary arterial hypertension: a randomized, double-blind study with open-label extension

(2017) Carmine Dario Vizza et al.   BMC Pulmonary Medicine

CCL2 nitration is a negative regulator of chemokine-mediated inflammation

(2017) Catriona E. Barker et al.   Scientific Reports

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

(2016) Harini Raghu et al.   ANNALS OF THE RHEUMATIC DISEASES

Resveratrol alleviate hypoxic pulmonary hypertension via anti-inflammation and anti-oxidant pathways in rats

(2016) Dunquan Xu et al.   International Journal of Medical Sciences

Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems

(2016) Jason Pellman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway

(2015) Yuanzhou He et al.   EXPERIMENTAL CELL RESEARCH

Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension

(2014) Marlene Rabinovitch et al.   CIRCULATION RESEARCH

Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats

(2014) Lamiaa A. Ahmed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

CCR2 Deficiency, Dysregulation of Notch Signaling, and Spontaneous Pulmonary Arterial Hypertension

(2013) Yen-Rei A. Yu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Resveratrol downregulates acute pulmonary thromboembolism-induced pulmonary artery hypertension via p38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 signaling in rats

(2012) Chen Chun et al.   LIFE SCIENCES

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats

(2010) Giselle C. Meléndez et al.   HYPERTENSION

Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats

(2009) Mohsen Imenshahidi et al.   PHYTOTHERAPY RESEARCH