Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during aging

Phosphoglycerate Mutase 5 Knockdown Alleviates Neuronal Injury After Traumatic Brain Injury Through Drp1-Mediated Mitochondrial Dysfunction

(2020) Yuhua Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics

(2020) Bo Yu et al.   Nature Communications

Empagliflozin alleviated mitochondrial fission via decreasing PGAM5.

(2020) Xiangyang Liu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Mitophagy, Mitochondrial Homeostasis, and Cell Fate

(2020) Kaili Ma et al.   Frontiers in Cell and Developmental Biology

Mitofusin1 in oocyte is essential for female fertility

(2019) Xiaojing Hou et al.   Redox Biology

Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate

(2019) Kaili Ma et al.   CELL DEATH AND DIFFERENTIATION

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Dehydroepiandrosterone Ameliorates Abnormal Mitochondrial Dynamics and Mitophagy of Cumulus Cells in Poor Ovarian Responders

(2018) Chia-Jung Li et al.   Journal of Clinical Medicine

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Low MFN2 expression related to ageing in granulosa cells is associated with assisted reproductive technology outcome

(2018) Lingjuan Wang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The Application of Dehydroepiandrosterone on Improving Mitochondrial Function and Reducing Apoptosis of Cumulus Cells in Poor Ovarian Responders

(2017) Li-Te Lin et al.   International Journal of Medical Sciences

Dehydroepiandrosterone as a potential agent to slow down ovarian aging

(2017) Li-Te Lin et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Development of a Postcolumn Infused-Internal Standard Liquid Chromatography Mass Spectrometry Method for Quantitative Metabolomics Studies

(2017) Hsiao-Wei Liao et al.   JOURNAL OF PROTEOME RESEARCH

“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content

(2016) Anna Picca et al.   EXPERIMENTAL GERONTOLOGY

Ovarian ageing: the role of mitochondria in oocytes and follicles

(2016) Pascale May-Panloup et al.   HUMAN REPRODUCTION UPDATE

Cumulus Cell Mitochondrial Resistance to Stress In Vitro Predicts Oocyte Development During Assisted Reproduction

(2016) Daniel A. Dumesic et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitofusins, from Mitochondria to Metabolism

(2016) Emilie Schrepfer et al.   MOLECULAR CELL

Mitochondrial proteolysis: Its emerging roles in stress responses

(2015) Shiori Sekine et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health

(2015) Daniel A. Dumesic et al.   FERTILITY AND STERILITY

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

(2015) Raymond Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling

(2015) Young Jun Kang et al.   Nature Communications

Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution

(2015) Wenjuan Xu et al.   Oncotarget

Mitochondrial Fission Factor Drp1 Maintains Oocyte Quality via Dynamic Rearrangement of Multiple Organelles

(2014) Osamu Udagawa et al.   CURRENT BIOLOGY

Minireview: Metabolism of Female Reproduction: Regulatory Mechanisms and Clinical Implications

(2014) Emre Seli et al.   MOLECULAR ENDOCRINOLOGY

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder

(2014) Wei Lu et al.   Nature Communications

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

The contribution of mitochondrial function to reproductive aging

(2011) Yaakov Bentov et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Automatic Morphological Subtyping Reveals New Roles of Caspases in Mitochondrial Dynamics

(2011) Jyh-Ying Peng et al.   PLoS Computational Biology

The Role of Mitochondrial DNA Copy Number in Mammalian Fertility1

(2010) Timothy Wai et al.   BIOLOGY OF REPRODUCTION

Impaired Mitochondrial Function in the Preimplantation Embryo Perturbs Fetal and Placental Development in the Mouse1

(2010) Sarah L. Wakefield et al.   BIOLOGY OF REPRODUCTION

The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome

(2010) Zhongwei Huang et al.   MOLECULAR HUMAN REPRODUCTION

The pivotal role of glucose metabolism in determining oocyte developmental competence

(2010) Melanie L Sutton-McDowall et al.   REPRODUCTION

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality

(2008) Robert B. Gilchrist et al.   HUMAN REPRODUCTION UPDATE

Prevalence of mitochondrial DNA disease in adults

(2007) Andrew M. Schaefer et al.   ANNALS OF NEUROLOGY