Proper control of R‐loop homeostasis is required for maintenance of gene expression and neuronal function during aging

Gene Size Matters: An Analysis of Gene Length in the Human Genome

(2021) Inês Lopes et al.   Frontiers in Genetics

In vivo tissue-specific chromatin profiling in Drosophila melanogaster using GFP-tagged nuclei

(2021) Juan Jauregui-Lozano et al.   GENETICS

Emerging roles for R-loop structures in the management of topological stress

(2020) Frederic Chedin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2

(2020) Célia Alecki et al.   Nature Communications

Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity

(2020) Yuyoung Joo et al.   Nature Communications

R-Loop Physiology and Pathology: A Brief Review

(2020) Ryan Patrick Mackay et al.   DNA AND CELL BIOLOGY

BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms

(2020) Yanhui Hu et al.   G3-Genes Genomes Genetics

Proper splicing contributes to visual function in the aging Drosophila eye

(2018) Rachel Stegeman et al.   AGING CELL

R-loop generation during transcription: Formation, processing and cellular outcomes

(2018) Boris P. Belotserkovskii et al.   DNA REPAIR

S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation

(2016) Lamia Wahba et al.   GENES & DEVELOPMENT

Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals

(2016) Lionel A. Sanz et al.   MOLECULAR CELL

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

(2016) Yves Pommier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Topoisomerases and the regulation of neural function

(2016) Peter J. McKinnon   NATURE REVIEWS NEUROSCIENCE

Genetic architecture of natural variation in visual senescence inDrosophila

(2016) Mary Anna Carbone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Length Matters in Neurons

(2015) Mark J. Zylka et al.   NEURON

Head-to-head antisense transcription and R-loop formation promotes transcriptional activation

(2015) Raquel Boque-Sastre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation

(2014) Yanzhong Yang et al.   MOLECULAR CELL

R-loops induce repressive chromatin marks over mammalian gene terminators

(2014) Konstantina Skourti-Stathaki et al.   NATURE

Out of Balance: R-loops in Human Disease

(2014) Matthias Groh et al.   PLoS Genetics

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Topoisomerases facilitate transcription of long genes linked to autism

(2013) Ian F. King et al.   NATURE

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

(2013) Dongyi Xu et al.   NATURE NEUROSCIENCE

R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters

(2012) Paul A. Ginno et al.   MOLECULAR CELL

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

Distinct Signature of Altered Homeostasis in Aging Rod Photoreceptors: Implications for Retinal Diseases

(2010) Sunil K. Parapuram et al.   PLoS One