Article
Nanoscience & Nanotechnology
Xiaoyun Li, Rui Wu, Huan Chen, Ting Li, Huiming Jiang, Xingquan Xu, Xueting Tang, Mimi Wan, Chun Mao, Dongquan Shi
Summary: This near-infrared light-driven multifunctional micromotor can rapidly target damaged blood vessels and release different drugs, promoting penetration into plaque sites through motion effects and achieving photothermal ablation of inflammatory macrophages through heat effects. In vivo experiments have demonstrated that these micromotors can provide good therapeutic effects for atherosclerosis.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Qing Liu, Hong-Bo Cheng, Rui Ma, Mingming Yu, Yuanyu Huang, Lele Li, Jian Zhao
Summary: A near-infrared light-guided DNA nanodevice is developed for precise drug delivery and tumor therapy. The nanodevice consists of GC-rich DNA duplexes with a UV light labile moiety and upconversion nanoparticles. Upon NIR light irradiation, the nanoparticles emit UV light to break the pho-tolabile moiety, resulting in controlled drug release and fluorescence signal recovery. This modular strategy enables remotely controlled drug delivery and in situ imaging.
Review
Chemistry, Inorganic & Nuclear
Longbo Jiang, Jinjuan Yang, Shaoyu Zhou, Hanbo Yu, Jie Liang, Wei Chu, Hui Li, Hou Wang, Zhibin Wu, Xingzhong Yuan
Summary: In order to enhance the efficiency of g-C3N4 photocatalysts under solar light (UV about 5%, visible light about 43%, NIR light about 52%), recent progress of NIR-driven g-C3N4 based photocatalysts has been reviewed. Various strategies have been summarized to broaden the light absorption of g-C3N4 to NIR light region, and the diverse photocatalytic applications of NIR-driven g-C3N4 photocatalysts have been outlined.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Chang Xu, Jiachen Sun, Miaomiao Tian, Jingwen Cui, Dingyuan Jiang, Hao Deng, Dan Li, Xifan Mei
Summary: Spinal cord injury is a complex neurological disorder with serious socioeconomic implications. Near-Infrared light-assisted therapy for SCI shows great promise in anti-inflammation and tissue regeneration effects. By summarizing the reported strategies, we can advance the research on NIR adjuvant therapy for SCI.
PROCESS BIOCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Chuangui Sheng, Fangzhi Yu, Youming Feng, Ming Gao, Wei Li, Lele Li, Jian Zhao
Summary: Metal-organic frameworks (MOFs) are used as a promising platform for protein delivery due to their high loading capacity and tunable functionality. However, the controlled release of proteins from MOFs-based nanocarriers is still a challenge. In this study, a MOFs-based protein delivery system that can precisely control protein release using near-infrared (NIR) light is reported. The system involves the encapsulation of proteins and upconversion nanoparticles (UCNPs) within MOFs and the use of NIR light to trigger the release of the proteins.
Article
Multidisciplinary Sciences
Qingle Ma, Chenlu Yao, Yi Wu, Heng Wang, Qin Fan, Qianyu Yang, Jialu Xu, Huaxing Dai, Yue Zhang, Fang Xu, Ting Lu, Jennifer K. Dowling, Chao Wang
Summary: The neurological syndromes after severe acute pneumonia are partly caused by the translocation of endogenous bacteria from the lung to the brain during pneumonia. The study found similarities in the bacterial species between the brain and lungs, indicating that the bacteria in the brain may originate from the lungs. The impairment of lung-blood and brain-blood barriers allows endogenous lung bacteria to invade the brain, leading to bacterial-induced disruption of brain homeostasis.
Review
Multidisciplinary Sciences
Christopher T. Jackson, Sanghwa Jeong, Gabriel F. Dorlhiac, Markita P. Landry
Summary: Near-infrared (NIR) luminescent materials have gained significant interest for imaging and optics applications in biology, chemistry, and physics. Despite potential, their development is hindered by various issues. This review explores emerging trends in promising NIR materials and emphasizes the importance of a comprehensive understanding of their properties for innovative applications in biological and physical sciences.
Article
Biotechnology & Applied Microbiology
Yoo-Seung Ko, Eun-Ji Gi, Sungsu Lee, Hyong-Ho Cho
Summary: This study aimed to investigate the anti-inflammatory effects of red and near-infrared (NIR) LED irradiation on lipopolysaccharide (LPS)-induced otitis media (OM) in rats, human middle ear epithelial cells (HMEECs), and murine macrophage cells (RAW 264.7). The results showed that red and NIR LED irradiation effectively reduced congestion and inflammation caused by LPS-induced OM, decreased the production of pro-inflammatory cytokines, and worked through the inhibition of the MAPK signaling pathway.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Engineering, Biomedical
Gaizhen Kuang, Hongtong Lu, Shasha He, Hejian Xiong, Jie Yu, Qingfei Zhang, Yubin Huang
Summary: Multifunctional nanoparticles combining multiple imaging modes and NIR light-activated drug/gene delivery have great potential in cancer therapy, displaying excellent therapeutic efficacy both in vitro and in vivo.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Engineering, Environmental
Renli Yin, Binghua Jing, Shaoxiong He, Jiayue Hu, Gang Lu, Zhimin Ao, Chuanyi Wang, Mingshan Zhu
Summary: The use of molybdenum disulphide in the activation of peroxydisulfate under near infrared light irradiation showcases the potential of light-to-heat conversion for environmental remediation. The observed reaction rates and proposed mechanism indicate a significant enhancement in efficiency and a new pathway towards pollution control. The development of a flexible photothermal membrane for practical application further demonstrates the possibilities for utilizing solar energy and novel approaches in environmental cleanup.
Review
Materials Science, Multidisciplinary
Siyi Wang, Feilong Wang, Xiao Zhao, Fan Yang, Yuqian Xu, Fanyu Yan, Dandan Xia, Yunsong Liu
Summary: Bone tissue engineering (BTE) utilizes polymers as effective materials for treating bone defects. The photothermal effects of near-infrared (NIR) light can promote osteogenesis and have additional benefits. Combining polymer scaffolds with NIR light-assisted photothermal therapy (PTT) results in positive bone regeneration outcomes.
MATERIALS & DESIGN
(2022)
Article
Nanoscience & Nanotechnology
Lynn M. Stevens, Clotilde Tagnon, Zachariah A. Page
Summary: The use of low-intensity, long-wavelength near-infrared light for 3D printing can expand the range of materials and include biological components and nanoparticles. This study demonstrates the use of a photosystem that enables rapid photocuring with low-intensity near-infrared light. By optimizing the resin composition and printing parameters, high speed and resolution 3D printing is achieved.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Lei Chen, Gaigai Li, Xingxing Wang, Jinbo Li, Yan Zhang
Summary: This study developed a PSNA for carrier-free and NIR photocontrolled self-delivery of siRNA and ASO, which could selectively release therapeutic agents in tumor cells under NIR light irradiation. PSNA showed promising potential for cancer therapy by combining gene therapy and photodynamic therapy.
Review
Biochemistry & Molecular Biology
Shang Jia, Ellen M. Sletten
Summary: This Review highlights recent developments in synthetic far-red and near-infrared photocages and photoswitches and their current and potential applications at the interface of chemistry and biology.
ACS CHEMICAL BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Philipp Neidinger, Joshua Davis, Dominik Voll, Esa A. Jaatinen, Sarah L. Walden, Andreas N. Unterreiner, Christopher Barner-Kowollik
Summary: This study introduces a gold nanorod-driven methodology to induce free radical polymerization in water using near infrared light. The process utilizes photothermal conversion and heat transfer to generate radicals, allowing control over the molecular weight and reaction conversion of the polymers. The results demonstrate the potential of this initiation mechanism for inducing polymerization in biological environments.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Neurosciences
Ye He, Zhi-Heng Zheng, Jin Zhou, Ping Hu, Bo-Wei Huang, Wei-Zhu Liu, Wen-Jie You, Han-Qing Pan, Bing-Xing Pan, Wen-Hua Zhang
Article
Multidisciplinary Sciences
Wei-Zhu Liu, Wen-Hua Zhang, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan
NATURE COMMUNICATIONS
(2020)
Article
Immunology
Zhi-Heng Zheng, Jiang-Long Tu, Xiao-Han Li, Qing Hua, Wei-Zhu Liu, Yu Liu, Bing-Xing Pan, Ping Hu, Wen -Hua Zhang
Summary: Excessive inflammatory responses are linked to psychiatric diseases, affecting neural plasticity in the amygdala and leading to anxiety and depression symptoms.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Nanoscience & Nanotechnology
Mingchuan Yu, Di Wang, Da Zhong, Weichang Xie, Jun Luo
Summary: This study found that exogenous adropin encapsulated in ROS-responsive nanocapsules can improve renal function, lipid metabolism, and oxidative stress levels in diabetic kidney disease (DKD) patients. The study also found that enhancing mitochondrial function can be achieved by activating neuronatin to improve lipid metabolism and inhibit translocator protein activity.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Yu Liu, Da Zhong, Yizhe He, Junkai Jiang, Weichang Xie, Zhibo Tang, Jianbin Qiu, Jun Luo, Xiaolei Wang
Summary: A photoresponsive upconversion cyanobacterium nanocapsule has been developed for the prevention and treatment of MI, with the potential to provide a highly effective and targeted approach.