Nanotechnology Enables Novel Modalities for Neuromodulation

Micro-coil probes for magnetic intracortical neural stimulation: Trade-offs in materials and design

(2021) Krishnan Thyagarajan et al.   APL Materials

Nonresonant powering of injectable nanoelectrodes enables wireless deep brain stimulation in freely moving mice

(2021) K. L. Kozielski et al.   Science Advances

Non-contact long-range magnetic stimulation of mechanosensitive ion channels in freely moving animals

(2021) Jung-uk Lee et al.   NATURE MATERIALS

The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics

(2021) Eve McGlynn et al.   Advanced Science

3D‐Printed Soft Magnetoelectric Microswimmers for Delivery and Differentiation of Neuron‐Like Cells

(2020) Mei Dong et al.   ADVANCED FUNCTIONAL MATERIALS

All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1

(2020) Linlin Z. Fan et al.   CELL

A wireless millimetre-scale implantable neural stimulator with ultrasonically powered bidirectional communication

(2020) David K. Piech et al.   Nature Biomedical Engineering

Biointegrated and Wirelessly Powered Implantable Brain Devices: A Review

(2020) Rupam Das et al.   IEEE Transactions on Biomedical Circuits and Systems

In situ electrochemical generation of nitric oxide for neuronal modulation

(2020) Jimin Park et al.   Nature Nanotechnology

Label-free optical detection of bioelectric potentials using electrochromic thin films

(2020) Felix S. Alfonso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Challenges for Therapeutic Applications of Opsin-Based Optogenetic Tools in Humans

(2020) Yi Shen et al.   Frontiers in Neural Circuits

Deep brain optogenetics without intracranial surgery

(2020) Ritchie Chen et al.   NATURE BIOTECHNOLOGY

Ultrasound Technologies for Imaging and Modulating Neural Activity

(2020) Claire Rabut et al.   NEURON

MagNI: A Magnetoelectrically Powered and Controlled Wireless Neurostimulating Implant

(2020) Zhanghao Yu et al.   IEEE Transactions on Biomedical Circuits and Systems

Assembling human brain organoids

(2019) Sergiu P. Paşca   SCIENCE

Near-Infrared-Light Activatable Nanoparticles for Deep-Tissue-Penetrating Wireless Optogenetics

(2019) Nuo Yu et al.   Advanced Healthcare Materials

Deep brain stimulation: current challenges and future directions

(2019) Andres M. Lozano et al.   Nature Reviews Neurology

Bioinspired neuron-like electronics

(2019) Xiao Yang et al.   NATURE MATERIALS

Scalable ultrasmall three-dimensional nanowire transistor probes for intracellular recording

(2019) Yunlong Zhao et al.   Nature Nanotechnology

An atlas of nano-enabled neural interfaces

(2019) Héctor Acarón Ledesma et al.   Nature Nanotechnology

Engineering a Genetically Encoded Magnetic Protein Crystal

(2019) Thomas L. Li et al.   NANO LETTERS

Remotely controlled chemomagnetic modulation of targeted neural circuits

(2019) Siyuan Rao et al.   Nature Nanotechnology

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons

(2019) Jeffrey Abbott et al.   Nature Biomedical Engineering

Microstructured thin-film electrode technology enables proof of concept of scalable, soft auditory brainstem implants

(2019) Nicolas Vachicouras et al.   Science Translational Medicine

Activating newborn neurons suppresses depression and anxiety-like behaviors

(2019) Elif Tunc-Ozcan et al.   Nature Communications

Sonogenetic Modulation of Cellular Activities Using an Engineered Auditory-Sensing Protein

(2019) Yao-Shen Huang et al.   NANO LETTERS

Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics

(2019) Xiang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrasound Elicits Behavioral Responses through Mechanical Effects on Neurons and Ion Channels in a Simple Nervous System

(2018) Jan Kubanek et al.   JOURNAL OF NEUROSCIENCE

Noninvasive neuromodulation and thalamic mapping with low-intensity focused ultrasound

(2018) Robert F. Dallapiazza et al.   JOURNAL OF NEUROSURGERY

Ultrasonic Neuromodulation Causes Widespread Cortical Activation via an Indirect Auditory Mechanism

(2018) Tomokazu Sato et al.   NEURON

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

Acoustically targeted chemogenetics for the non-invasive control of neural circuits

(2018) Jerzy O. Szablowski et al.   Nature Biomedical Engineering

Rational design of silicon structures for optically controlled multiscale biointerfaces

(2018) Yuanwen Jiang et al.   Nature Biomedical Engineering

Targeted neurotechnology restores walking in humans with spinal cord injury

(2018) Fabien B. Wagner et al.   NATURE

Miniature ultrasound ring array transducers for transcranial ultrasound neuromodulation of freely-moving small animals

(2018) Hyunggug Kim et al.   Brain Stimulation

Micro-Coil Design Influences the Spatial Extent of Responses to Intracortical Magnetic Stimulation

(2018) Seung Woo Lee et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions

(2017) Raag D. Airan et al.   NANO LETTERS

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

One-step optogenetics with multifunctional flexible polymer fibers

(2017) Seongjun Park et al.   NATURE NEUROSCIENCE

Comparison of the induced fields using different coil configurations during deep transcranial magnetic stimulation

(2017) Mai Lu et al.   PLoS One

Neural recording and modulation technologies

(2017) Ritchie Chen et al.   Nature Reviews Materials

Tissue–electronics interfaces: from implantable devices to engineered tissues

(2017) Ron Feiner et al.   Nature Reviews Materials

Near-infrared fluorophores for biomedical imaging

(2017) Guosong Hong et al.   Nature Biomedical Engineering

Glial responses to implanted electrodes in the brain

(2017) Joseph W. Salatino et al.   Nature Biomedical Engineering

Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications

(2016) Xiang Wu et al.   ACS Nano

Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces

(2016) Yuanwen Jiang et al.   NATURE MATERIALS

Stable long-term chronic brain mapping at the single-neuron level

(2016) Tian-Ming Fu et al.   NATURE METHODS

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Physical limits to magnetogenetics

(2016) Markus Meister   eLife

Transcranial magnetic stimulation (TMS) inhibits cortical dendrites

(2016) Sean C Murphy et al.   eLife

Implantable microcoils for intracortical magnetic stimulation

(2016) S. W. Lee et al.   Science Advances

Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation

(2015) Attilio Marino et al.   ACS Nano

Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics

(2015) Jae-Woong Jeong et al.   CELL

Magnetoelectric ‘spin’ on stimulating the brain

(2015) Rakesh Guduru et al.   Nanomedicine

Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo

(2015) Andres Canales et al.   NATURE BIOTECHNOLOGY

A magnetic protein biocompass

(2015) Siying Qin et al.   NATURE MATERIALS

Photosensitivity of Neurons Enabled by Cell-Targeted Gold Nanoparticles

(2015) João L. Carvalho-de-Souza et al.   NEURON

Treating brain disorders with neuromodulation

(2015) Y. Temel et al.   SCIENCE

Electronic dura mater for long-term multimodal neural interfaces

(2015) I. R. Minev et al.   SCIENCE

Wireless magnetothermal deep brain stimulation

(2015) R. Chen et al.   SCIENCE

Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans

(2014) Wynn Legon et al.   NATURE NEUROSCIENCE

Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics

(2013) T.-i. Kim et al.   SCIENCE

Activation of the central nervous system induced by micro-magnetic stimulation

(2013) Hyun-Joo Park et al.   Nature Communications

Microscopic magnetic stimulation of neural tissue

(2012) Giorgio Bonmassar et al.   Nature Communications

Ultrasonic neuromodulation by brain stimulation with transcranial ultrasound

(2011) Yusuf Tufail et al.   Nature Protocols

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Remote control of ion channels and neurons through magnetic-field heating of nanoparticles

(2010) Heng Huang et al.   Nature Nanotechnology

Remote control of cellular behaviour with magnetic nanoparticles

(2008) Jon Dobson   Nature Nanotechnology