Reprogramming Tumor‐Associated Macrophages via ROS‐Mediated Novel Mechanism of Ultra‐Small Cu 2− x Se Nanoparticles to Enhance Anti‐Tumor Immunity

Copper Sulfide Nanoparticle‐Redirected Macrophages for Adoptive Transfer Therapy of Melanoma

(2021) Jiaojiao Xu et al.   ADVANCED FUNCTIONAL MATERIALS

Oxidative stress-induced senescence mediates inflammatory and fibrotic phenotypes in fibroblasts from systemic sclerosis patients

(2021) Ozge Kizilay Mancini et al.   RHEUMATOLOGY

M2-Like Tumor-Associated Macrophage-Targeted Codelivery of STAT6 Inhibitor and IKKβ siRNA Induces M2-to-M1 Repolarization for Cancer Immunotherapy with Low Immune Side Effects

(2020) Hong Xiao et al.   ACS Central Science

Acceptor Engineering for Optimized ROS Generation Facilitates Reprogramming Macrophages to M1 Phenotype in Photodynamic Immunotherapy

(2020) Guang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Combining Nanomedicine and Immunotherapy

(2019) Yang Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Light-Enhanced O2-Evolving Nanoparticles Boost Photodynamic Therapy To Elicit Antitumor Immunity

(2019) Tingting Wang et al.   ACS Applied Materials & Interfaces

Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway

(2019) Zhengying Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy

(2019) Rong-Hui Deng et al.   ACS Nano

Artificial Natural Killer Cells for Specific Tumor Inhibition and Renegade Macrophage Re‐Education

(2019) Mei‐Zhen Zou et al.   ADVANCED MATERIALS

Progress on Modulating Tumor‐Associated Macrophages with Biomaterials

(2019) Meilyn Sylvestre et al.   ADVANCED MATERIALS

Nanomedicine‐Based Immunotherapy for the Treatment of Cancer Metastasis

(2019) Pengcheng Zhang et al.   ADVANCED MATERIALS

Boosting H 2 O 2 ‐Guided Chemodynamic Therapy of Cancer by Enhancing Reaction Kinetics through Versatile Biomimetic Fenton Nanocatalysts and the Second Near‐Infrared Light Irradiation

(2019) Tingting Wang et al.   ADVANCED FUNCTIONAL MATERIALS

CSF1R‐ and SHP2‐Inhibitor‐Loaded Nanoparticles Enhance Cytotoxic Activity and Phagocytosis in Tumor‐Associated Macrophages

(2019) Anujan Ramesh et al.   ADVANCED MATERIALS

Intra/Extracellular Lactic Acid Exhaustion for Synergistic Metabolic Therapy and Immunotherapy of Tumors

(2019) Fan Gao et al.   ADVANCED MATERIALS

Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases

(2019) Wei He et al.   ADVANCED DRUG DELIVERY REVIEWS

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

(2018) Degao Chen et al.   Nature Communications

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Selenium and copper interaction at supra-nutritional level affecting blood parameters including immune response against P. multocida antigen in Murrah buffalo (Bubalus bubalis) calves

(2018) Vishal Mudgal et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

(2018) Hua Wang et al.   NATURE MATERIALS

Wilson disease

(2018) Anna Członkowska et al.   Nature Reviews Disease Primers

Reprogramming Tumor-Associated Macrophages by Nanoparticle-Based Reactive Oxygen Species Photogeneration

(2018) Changrong Shi et al.   NANO LETTERS

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity

(2017) Lin Hu et al.   Nature Communications

Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu2−xSe Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer

(2016) Shaohua Zhang et al.   ADVANCED MATERIALS

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4

(2016) Verena Schuette et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling

(2016) Yan-Xiao Ji et al.   Nature Communications

Surfactin inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and inflammasomes in macrophages for adjuvant activity

(2016) Ping Gan et al.   Scientific Reports

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression

(2016) Ruihua Ma et al.   OncoImmunology

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

(2015) Geming Lu et al.   Nature Communications

The dual role of iNOS in cancer

(2015) Federica Vannini et al.   Redox Biology

Combinatorial Photothermal and Immuno Cancer Therapy Using Chitosan-Coated Hollow Copper Sulfide Nanoparticles

(2014) Liangran Guo et al.   ACS Nano

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

IKKβ is an IRF5 kinase that instigates inflammation

(2014) Junyao Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain

(2014) Takahiro Masuda et al.   Nature Communications

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination

(2013) Xiaofei Zhang et al.   CELL RESEARCH

Peroxiredoxin I is a ROS/p38 MAPK-dependent inducible antioxidant that regulates NF-κB-mediated iNOS induction and microglial activation

(2013) Sun-Uk Kim et al.   JOURNAL OF NEUROIMMUNOLOGY

IRF5 Is a Specific Marker of Inflammatory MacrophagesIn Vivo

(2013) Miriam Weiss et al.   MEDIATORS OF INFLAMMATION

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveosomal Oxidative Stress Causes Src-p21rasActivation and Lysine 63 TRAF6 Protein Polyubiquitination in Iron-induced M1 Hepatic Macrophage Activation

(2012) Shuping Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propionibacterium acnes-induced iNOS and COX-2 protein expression via ROS-dependent NF-κB and AP-1 activation in macrophages

(2012) Hsiou-Hsin Tsai et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Functional Regulation of MyD88-Activated Interferon Regulatory Factor 5 by K63-Linked Polyubiquitination

(2008) M. Y. Balkhi et al.   MOLECULAR AND CELLULAR BIOLOGY

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL