Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers

Coagulation-Inspired Direct Fibrinogen Assay Using Plasmonic Nanoparticles Functionalized with Red Blood Cell Membranes

(2021) Insu Kim et al.   ACS Nano

Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers

(2021) Jacob S. Brenner et al.   Annual Review of Biomedical Engineering

Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic

(2021) Xuqing Zhang et al.   Nature Communications

The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation

(2020) Thai Thanh Hoang Thi et al.   Polymers

Ongoing Developments and Clinical Progress in Drug-Loaded Red Blood Cell Technologies

(2020) Luigia Rossi et al.   BIODRUGS

Harnessing CD47 mimicry to inhibit phagocytic clearance and enhance anti-tumor efficacy of nanoliposomal doxorubicin

(2020) Seyed Mohammad Gheibi Hayat et al.   Expert Opinion on Drug Delivery

Development of long circulating magnetic particle imaging tracers: use of novel magnetic nanoparticles and entrapment into human erythrocytes

(2020) Antonella Antonelli et al.   Nanomedicine

Liposome Circulation Time is Prolonged by CD47 Coating

(2020) Seyed Mohammad Gheibi Hayat et al.   PROTEIN AND PEPTIDE LETTERS

Erythrocytes as Carriers: From Drug Delivery to Biosensors

(2020) Larisa Koleva et al.   Pharmaceutics

Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics

(2020) Patrick M. Glassman et al.   Pharmaceutics

Recent advancements in liposome technology

(2020) Nina Filipczak et al.   ADVANCED DRUG DELIVERY REVIEWS

Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function

(2020) Anvay Ukidve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming the rapid clearance of thrombolytics by nanoparticle encapsulation and anchoring to circulating red blood cells

(2020) Mohit Pratap Singh et al.   JOURNAL OF CONTROLLED RELEASE

Magnetic Manipulation of Blood Conductivity with Superparamagnetic Iron Oxide-Loaded Erythrocytes

(2019) Gavin R. Philips et al.   ACS Applied Materials & Interfaces

Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55

(2019) Geoffrey Gifford et al.   JOURNAL OF CONTROLLED RELEASE

Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain

(2019) Oscar A. Marcos-Contreras et al.   JOURNAL OF CONTROLLED RELEASE

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy

(2019) Michelle Levene et al.   Journal of Clinical Medicine

PEGylated liposomes: immunological responses

(2019) Marwa Mohamed et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Erythrocyte Encapsulated Thymidine Phosphorylase for the Treatment of Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy: Study Protocol for a Multi-Centre, Multiple Dose, Open Label Trial

(2019) Bax et al.   Journal of Clinical Medicine

An ImmunoPEGliposome for Targeted Antimalarial Combination Therapy at the Nanoscale

(2019) Arnau Biosca et al.   Pharmaceutics

The hard protein corona of stealth liposomes is sparse

(2019) Kasper Kristensen et al.   JOURNAL OF CONTROLLED RELEASE

Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis

(2019) Zongmin Zhao et al.   Science Advances

Erythrocytes as carriers of immunoglobulin-based therapeutics

(2019) Weihang Ji et al.   Acta Biomaterialia

Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing

(2018) Joseph Hawksworth et al.   EMBO Molecular Medicine

Physicochemical Study of the Protein-Liposome Interactions: Influence of Liposome Composition and Concentration on Protein Binding

(2018) Foteini Papageorgiou et al.   JOURNAL OF LIPOSOME RESEARCH

A new therapy prevents intellectual disability in mouse with phenylketonuria

(2018) Tiziana Pascucci et al.   MOLECULAR GENETICS AND METABOLISM

Ferucarbotran-loaded red blood cells as long circulating MRI contrast agents: first in vivo results in mice

(2018) Antonella Antonelli et al.   Nanomedicine

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

(2018) Jacob S. Brenner et al.   Nature Communications

Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies.

(2018) Elizabeth D Hood et al.   BIOCONJUGATE CHEMISTRY

Vascular immunotargeting: take the highway to the first exit

(2018) Vladimir Muzykantov et al.   HEPATOLOGY

Liposome: composition, characterization, preparation, and recent innovation in clinical applications

(2018) Kamel S. Ahmed et al.   JOURNAL OF DRUG TARGETING

Impact of PEGylated Nanoparticles on Tumor Targeted Drug Delivery

(2018) Fitya Syarifa Mozar et al.   CURRENT PHARMACEUTICAL DESIGN

Development of a flow-through USP 4 apparatus drug release assay for the evaluation of amphotericin B liposome

(2018) Jie Tang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cholesterol Increases Lipid Binding Rate and Changes Binding Behavior of Bacillus thuringiensis Cytolytic Protein

(2018) Sudarat Tharad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New drug candidates for liposomal delivery identified by computer modeling of liposomes' remote loading and leakage

(2017) Ahuva Cern et al.   JOURNAL OF CONTROLLED RELEASE

Liposomes containing cyclodextrins or meglumine to solubilize and improve the bioavailability of poorly soluble drugs

(2017) Carolina Aloisio et al.   JOURNAL OF MOLECULAR LIQUIDS

Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions

(2017) Jacob S. Brenner et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cancer drug delivery in the nano era: An overview and perspectives

(2017) Zhen Li et al.   ONCOLOGY REPORTS

Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease

(2017) Novalia Pishesha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin

(2017) Nai-Jia Huang et al.   Nature Communications

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems

(2016) Carlos H. Villa et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering erythrocytes for the modulation of drugs' and contrasting agents' pharmacokinetics and biodistribution

(2016) Luigia Rossi et al.   ADVANCED DRUG DELIVERY REVIEWS

Affinity Induced Surface Functionalization of Liposomes Using Cu-Free Click Chemistry

(2016) Martin Bak et al.   BIOCONJUGATE CHEMISTRY

Development of drug-loaded immunoliposomes for the selective targeting and elimination of rosetting Plasmodium falciparum- infected red blood cells

(2016) Ernest Moles et al.   JOURNAL OF CONTROLLED RELEASE

Erythrocyte-mediated delivery of recombinant enzymes

(2016) Vincenzo Leuzzi et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake

(2016) Lang Rao et al.   NANOTECHNOLOGY

Nanoparticle Attachment to Erythrocyte Via the Glycophorin A Targeted ERY1 Ligand Enhances Binding without Impacting Cellular Function

(2016) Kaustuv Sahoo et al.   PHARMACEUTICAL RESEARCH

Drug delivery by erythrocytes: “Primum non nocere”

(2016) Carlos H. Villa et al.   TRANSFUSION AND APHERESIS SCIENCE

The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy

(2015) Jonathan T. Sockolosky et al.   ADVANCED DRUG DELIVERY REVIEWS

Exploiting shape, cellular-hitchhiking and antibodies to target nanoparticles to lung endothelium: Synergy between physical, chemical and biological approaches

(2015) Aaron C. Anselmo et al.   BIOMATERIALS

New Developments in Liposomal Drug Delivery

(2015) Bhushan S. Pattni et al.   CHEMICAL REVIEWS

Preferential targeting of human erythrocytes infected with the malaria parasite Plasmodium falciparum via hexose transporter surface proteins

(2015) Kajal Devi Heikham et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Liposome functionalization with copper-free “click chemistry”

(2015) Erik Oude Blenke et al.   JOURNAL OF CONTROLLED RELEASE

Immunoliposome-mediated drug delivery to Plasmodium -infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy

(2015) Ernest Moles et al.   JOURNAL OF CONTROLLED RELEASE

The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes

(2015) Paul H. Kierstead et al.   JOURNAL OF CONTROLLED RELEASE

Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance

(2015) Lang Rao et al.   Small

Mechanical clearance of red blood cells by the human spleen: Potential therapeutic applications of a biomimetic RBC filtration method

(2015) J. Duez et al.   TRANSFUSION CLINIQUE ET BIOLOGIQUE

Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens

(2015) Alizée J. Grimm et al.   Scientific Reports

Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase

(2015) K. M. Lorentz et al.   Science Advances

Erythrocyte Membrane Is an Alternative Coating to Polyethylene Glycol for Prolonging the Circulation Lifetime of Gold Nanocages for Photothermal Therapy

(2014) Ji-Gang Piao et al.   ACS Nano

Liposomes as carriers of hydrophilic small molecule drugs: Strategies to enhance encapsulation and delivery

(2014) Josimar Oliveira Eloy et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Designer lipids for drug delivery: From heads to tails

(2014) Aditya G. Kohli et al.   JOURNAL OF CONTROLLED RELEASE

Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation

(2014) Melissa D. Howard et al.   JOURNAL OF CONTROLLED RELEASE

Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes

(2014) Rajesh Mukthavaram et al.   JOURNAL OF CONTROLLED RELEASE

Macrophage Depletion by Free Bisphosphonates and Zoledronate-Loaded Red Blood Cells

(2014) Raffaella Sabatino et al.   PLoS One

Remote loading of preencapsulated drugs into stealth liposomes

(2014) Surojit Sur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

(2014) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measurement of Posttransfusion Red Cell Survival With the Biotin Label

(2014) Donald M. Mock et al.   TRANSFUSION MEDICINE REVIEWS

Of macrophages and red blood cells; a complex love story

(2014) Djuna Z. de Back et al.   Frontiers in Physiology

Delivering Nanoparticles to Lungs while Avoiding Liver and Spleen through Adsorption on Red Blood Cells

(2013) Aaron C. Anselmo et al.   ACS Nano

Novel methods for liposome preparation

(2013) Yogita P. Patil et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Hyaluronic acid-coated liposomes for active targeting of gemcitabine

(2013) Silvia Arpicco et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A robust and quantitative method for tracking liposome contents after intravenous administration

(2013) Aditya G. Kohli et al.   JOURNAL OF CONTROLLED RELEASE

Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems

(2013) John C. Kraft et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

‘Marker-of-self’ functionalization of nanoscale particles through a top-down cellular membrane coating approach

(2013) Che-Ming J. Hu et al.   Nanoscale

Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor

(2013) Colin F. Greineder et al.   PLoS One

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Ligand-targeted liposome design: challenges and fundamental considerations

(2013) Gavin T. Noble et al.   TRENDS IN BIOTECHNOLOGY

Liposome: classification, preparation, and applications

(2013) Abolfazl Akbarzadeh et al.   Nanoscale Research Letters

Challenges in Development of Targeted Liposomal Therapeutics

(2012) Rupa R. Sawant et al.   AAPS Journal

Multifunctional nanocarriers

(2012) Vladimir P. Torchilin   ADVANCED DRUG DELIVERY REVIEWS

Cancer nanomedicines: So many papers and so few drugs!

(2012) Vincent J. Venditto et al.   ADVANCED DRUG DELIVERY REVIEWS

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

New Method for Site-Specific Modification of Liposomes with Proteins Using Sortase A-Mediated Transpeptidation

(2012) Xueqing Guo et al.   BIOCONJUGATE CHEMISTRY

Drug delivery carriers on the fringes: natural red blood cells versus synthetic multilayered capsules

(2012) Vladimir R Muzykantov   Expert Opinion on Drug Delivery

Enhanced active liposomal loading of a poorly soluble ionizable drug using supersaturated drug solutions

(2012) Sweta Modi et al.   JOURNAL OF CONTROLLED RELEASE

Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo

(2012) Elizabeth D. Hood et al.   JOURNAL OF CONTROLLED RELEASE

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Protein Encapsulation in Unilamellar Liposomes: High Encapsulation Efficiency and A Novel Technique to Assess Lipid-Protein Interaction

(2012) Xiaoming Xu et al.   PHARMACEUTICAL RESEARCH

Engineering antigens for in situ erythrocyte binding induces T-cell deletion

(2012) S. Kontos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flow-dependent channel formation in clots by an erythrocyte-bound fibrinolytic agent

(2011) K. C. Gersh et al.   BLOOD

Engineering erythrocytes to be erythrosensors: First steps

(2011) Mark A. Milanick et al.   BLOOD CELLS MOLECULES AND DISEASES

l-asparaginase loaded red blood cells in refractory or relapsing acute lymphoblastic leukaemia in children and adults: results of the GRASPALL 2005-01 randomized trial

(2011) Carine Domenech et al.   BRITISH JOURNAL OF HAEMATOLOGY

Microthrombosis after experimental subarachnoid hemorrhage: Time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan

(2011) Jared M. Pisapia et al.   EXPERIMENTAL NEUROLOGY

Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increasedin vivoactivity

(2011) Jerzy Gubernator   Expert Opinion on Drug Delivery

Immunophilin-loaded erythrocytes as a new delivery strategy for immunosuppressive drugs

(2011) Sara Biagiotti et al.   JOURNAL OF CONTROLLED RELEASE

Quantitative structure - property relationship modeling of remote liposome loading of drugs

(2011) Ahuva Cern et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity

(2011) Erez Koren et al.   JOURNAL OF CONTROLLED RELEASE

Shape and Biomechanical Characteristics of Human Red Blood Cells in Health and Disease

(2011) Monica Diez-Silva et al.   MRS BULLETIN

Encapsulation of superparamagnetic nanoparticles into red blood cells as new carriers of MRI contrast agents

(2011) Antonella Antonelli et al.   Nanomedicine

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Endothelial Delivery of Nanosized Catalase Immunoconjugates Protects Lung Grafts Donated After Cardiac Death

(2011) Gerhard Preissler et al.   TRANSPLANTATION

Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors

(2011) Sarah C. Ritter et al.   Biomedical Optics Express

The use of single chain Fv as targeting agents for immunoliposomes: an update on immunoliposomal drugs for cancer treatment

(2010) WW Cheng et al.   Expert Opinion on Drug Delivery

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers

(2010) Andres J. Calderon et al.   JOURNAL OF CONTROLLED RELEASE

Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig

(2010) William M. Armstead et al.   Pediatric Critical Care Medicine

Liposomes as ‘smart’ pharmaceutical nanocarriers

(2010) Rupa R. Sawant et al.   Soft Matter

Red blood cell (RBC) survival determined in humans using RBCs labeled at multiple biotin densities

(2010) Donald M. Mock et al.   TRANSFUSION

Targeted delivery of doxorubicin using stealth liposomes modified with transferrin

(2009) XueMing Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Red Blood Cells-Coupled tPA Prevents Impairment of Cerebral Vasodilatory Responses and Tissue Injury in Pediatric Cerebral Hypoxia/Ischemia through Inhibition of ERK MAPK Activation

(2009) William M Armstead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile

(2009) Juan-Carlos Murciano et al.   JOURNAL OF CONTROLLED RELEASE

Erythrocyte-Bound Tissue Plasminogen Activator is Neuroprotective in Experimental Traumatic Brain Injury

(2009) Sherman C. Stein et al.   JOURNAL OF NEUROTRAUMA

Flexible Filaments forin VivoImaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage

(2009) David A. Christian et al.   MOLECULAR PHARMACEUTICS

Red blood cell-mimicking synthetic biomaterial particles

(2009) N. Doshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opsonized erythrocyte ghosts for liver-targeted delivery of antisense oligodeoxynucleotides

(2008) Sang-Hee Kim et al.   BIOMATERIALS

Cerebrovascular Thromboprophylaxis in Mice by Erythrocyte-Coupled Tissue-Type Plasminogen Activator

(2008) Kristina Danielyan et al.   CIRCULATION

Multifunctional and stimuli-sensitive pharmaceutical nanocarriers

(2008) Vladimir Torchilin   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

PEGylation of Nanocarrier Drug Delivery Systems: State of the Art

(2008) Melissa D. Howard et al.   Journal of Biomedical Nanotechnology

New Biomimetic Constructs for Improved In Vivo Circulation of Superparamagnetic Nanoparticles

(2008) Antonella Antonelli et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Urokinase Plasminogen Activator Impairs SNP and PGE2 Cerebrovasodilation after Brain Injury through Activation of LRP and ERK MAPK

(2008) William M. Armstead et al.   JOURNAL OF NEUROTRAUMA

Anticancer Therapeutics: Targeting Macromolecules and Nanocarriers to Hyaluronan or CD44, a Hyaluronan Receptor

(2008) Virginia M. Platt et al.   MOLECULAR PHARMACEUTICS

Identification of Peptide Ligands Facilitating Nanoparticle Attachment to Erythrocytes

(2007) Sejal S. Hall et al.   BIOTECHNOLOGY PROGRESS

Effective anti-tumor activity of oxaliplatin encapsulated in transferrin–PEG-liposome

(2007) Ryo Suzuki et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS