Development of a hyperbranched polymer-based methotrexate nanomedicine for rheumatoid arthritis

Low-Fouling Fluoropolymers for Bioconjugation and In Vivo Tracking

(2020) Changkui Fu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methotrexate and its mechanisms of action in inflammatory arthritis

(2020) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

Proteins Conjugated with Sulfoxide-Containing Polymers Show Reduced Macrophage Cellular Uptake and Improved Pharmacokinetics

(2020) Ye Yu et al.   ACS Macro Letters

Current Perspectives on 89Zr-PET Imaging

(2020) Joon-Kee Yoon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Optimization and Development of Methotrexate- and Resveratrol-Loaded Nanoemulsion Formulation Using Box–Behnken Design for Rheumatoid Arthritis

(2020) Neelam Poonia et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats

(2020) Nirmal Marasini et al.   Nanomaterials

Increased Encapsulation Efficiency of Methotrexate in Liposomes for Rheumatoid Arthritis Therapy

(2020) Diana Guimarães et al.   Biomedicines

Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy

(2020) Lina Guo et al.   JOURNAL OF CONTROLLED RELEASE

Assessment of liver fibrosis markers in people with rheumatoid arthritis on methotrexate

(2020) Debbie A. Olsson‐White et al.   INTERNAL MEDICINE JOURNAL

Bioinspired Shielding Strategies for Nanoparticle Drug Delivery Applications

(2018) Neetu M. Gulati et al.   MOLECULAR PHARMACEUTICS

Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats: single-agent effects of alkaline phosphatase and synergistic effects in combination with methotrexate

(2018) Durga M.S.H. Chandrupatla et al.   Translational Research

Liver as a key organ in the supply, storage, and excretion of copper

(2018) Eve A Roberts et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Methotrexate mechanism in treatment of rheumatoid arthritis

(2018) Benjamin Friedman et al.   JOINT BONE SPINE

Endogenous sialic acid-engineered micelles: a multifunctional platform for on-demand methotrexate delivery and bone repair of rheumatoid arthritis

(2018) Xiao-Ling Xu et al.   Nanoscale

Precision Self-Assembly of Amphiphilic Random Copolymers into Uniform and Self-Sorting Nanocompartments in Water

(2016) Yuji Hirai et al.   MACROMOLECULES

Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases

(2016) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

Enhanced toxicity and cellular uptake of methotrexate-conjugated nanoparticles in folate receptor-positive cancer cells by decorating with folic acid-conjugated d -α-tocopheryl polyethylene glycol 1000 succinate

(2015) Varaporn Buraphacheep Junyaprasert et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Folate Receptor-Targeted Dendrimer-Methotrexate Conjugate for Inflammatory Arthritis

(2015) Rong Qi et al.   Journal of Biomedical Nanotechnology

Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats

(2015) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Nanomedicine delivers promising treatments for rheumatoid arthritis

(2015) Leena Kumari Prasad et al.   Nanomedicine

Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid

(2012) Bryan J Heard et al.   BMC MUSCULOSKELETAL DISORDERS

Investigation of nano lipid vesicles of methotrexate for anti-rheumatoid activity

(2012) Prabhakara Prabhu et al.   International Journal of Nanomedicine

Terminal functional glycopolymers via a combination of catalytic chain transfer polymerisation (CCTP) followed by three consecutive click reactions

(2012) Qiang Zhang et al.   Polymer Chemistry

Polyacrylate Dendrimer Nanoparticles: A Self-Adjuvanting Vaccine Delivery System

(2010) Mariusz Skwarczynski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Capping Methotrexate α-Carboxyl Groups Enhances Systemic Exposure and Retains the Cytotoxicity of Drug Conjugated PEGylated Polylysine Dendrimers

(2010) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

(2009) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities

(2008) Chelsea N. Salinas et al.   BIOMATERIALS