The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats

Stealth Coating of Nanoparticles in Drug-Delivery Systems

(2020) See Yee Fam et al.   Nanomaterials

Challenges in nanomedicine clinical translation

(2020) Josbert M. Metselaar et al.   Drug Delivery and Translational Research

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A Structure–Activity Comparison of Biodistribution

(2020) James Humphries et al.   BIOMACROMOLECULES

PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution

(2019) Zahid Hussain et al.   Drug Delivery and Translational Research

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

(2019) Lisa M. Kaminskas et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats

(2019) Shadabul Haque et al.   JOURNAL OF CONTROLLED RELEASE

Nanocarrier systems assembled from PEGylated hyperbranched poly(arylene oxindole)

(2019) Al Halifa Soultan et al.   EUROPEAN POLYMER JOURNAL

dendPoint: a web resource for dendrimer pharmacokinetics investigation and prediction

(2019) Lisa M. Kaminskas et al.   Scientific Reports

Hyperbranched polyglycerol nanostructures for anti-biofouling, multifunctional drug delivery, bioimaging and theranostic applications

(2019) Mahboobeh Jafari et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A comparison of the lung clearance kinetics of solid lipid nanoparticles and liposomes by following the 3 H-labelled structural lipids after pulmonary delivery in rats

(2018) Shadabul Haque et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization

(2018) Susan Hua et al.   Frontiers in Pharmacology

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

(2018) N. L. Fletcher et al.   CHEMICAL COMMUNICATIONS

Nanomedicines: The magic bullets reaching their target?

(2018) Beat Flühmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics

(2017) Yongmei Zhao et al.   MOLECULAR PHARMACEUTICS

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

(2017) Liyu Chen et al.   MOLECULAR PHARMACEUTICS

Challenges associated and approaches for successful translation of nanomedicines into commercial products

(2017) Vivek Agrahari et al.   Nanomedicine

Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site

(2017) Gemma M. Ryan et al.   Nanomedicine-Nanotechnology Biology and Medicine

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Cancer nanomedicines: oversold or underappreciated?

(2016) Roy van der Meel et al.   Expert Opinion on Drug Delivery

Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications

(2016) Anisha A. D’souza et al.   Expert Opinion on Drug Delivery

The Pharmacokinetics and Biodistribution of a 64 kDa PolyPEG Star Polymer After Subcutaneous and Pulmonary Administration to Rats

(2016) Song Yang Khor et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery

(2016) Nirmal Marasini et al.   Nanomedicine

Challenges of clinical translation in nanomedicine: A qualitative study

(2016) Priya Satalkar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging

(2016) Kewei Wang et al.   Polymer Chemistry

Skin toxicity in a patient with ovarian cancer treated with pegylated liposomal doxorubicin: A case report and review of the literature

(2016) Joanna Kubicka-Wołkowska et al.   Oncology Letters

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

(2015) Qingguo Xu et al.   ACS Nano

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats

(2015) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

In vitro metabolism, disposition, preclinical pharmacokinetics and prediction of human pharmacokinetics of DNDI-VL-2098, a potential oral treatment for Visceral Leishmaniasis

(2014) Rao Mukkavilli et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

PEG-Based Hyperbranched Polymer Theranostics: Optimizing Chemistries for Improved Bioconjugation

(2014) Aditya Ardana et al.   MACROMOLECULES

Synthesis of a multimodal molecular imaging probe based on a hyperbranched polymer architecture

(2014) Nathan R. B. Boase et al.   Polymer Chemistry

Doxorubicin-Conjugated PEGylated Dendrimers Show Similar Tumoricidal Activity but Lower Systemic Toxicity When Compared to PEGylated Liposome and Solution Formulations in Mouse and Rat Tumor Models

(2012) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Comparative pharmacokinetics of PAMAM-OH dendrimers and HPMA copolymers in ovarian tumor-bearing mice

(2012) S. Sadekar et al.   Drug Delivery and Translational Research

Synthesis of Biocompatible PEG-Based Star Polymers with Cationic and Degradable Core for siRNA Delivery

(2011) Hong Y. Cho et al.   BIOMACROMOLECULES

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties

(2011) Lisa M Kaminskas et al.   Nanomedicine

In vivo biodistribution and accumulation of 89Zr in mice

(2011) Diane S. Abou et al.   NUCLEAR MEDICINE AND BIOLOGY

Capping Methotrexate α-Carboxyl Groups Enhances Systemic Exposure and Retains the Cytotoxicity of Drug Conjugated PEGylated Polylysine Dendrimers

(2010) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Partly-PEGylated Poly-L-lysine Dendrimers Have Reduced Plasma Stability and Circulation Times Compared With Fully PEGylated Dendrimers

(2009) L.M. Kaminskas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

(2009) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Pharmacokinetics and biodistribution of near-infrared fluorescence polymeric nanoparticles

(2009) Zhi Yang et al.   NANOTECHNOLOGY

The Impact of Molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Polyl-Lysine Dendrimers

(2008) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS