Meckel’s and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible

Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model

(2016) Davide Komla-Ebri et al.   JOURNAL OF CLINICAL INVESTIGATION

Achondroplasia: Manifestations and Treatment

(2016) Eric D. Shirley et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

FGFR3 biology and skeletal disease

(2015) Jyoti Narayana et al.   CONNECTIVE TISSUE RESEARCH

Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation

(2015) Kai Yu et al.   DEVELOPMENTAL DYNAMICS

FGFR3 mutation causes abnormal membranous ossification in achondroplasia

(2014) Federico Di Rocco et al.   HUMAN MOLECULAR GENETICS

Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions

(2013) Kimberly L. Cooper et al.   NATURE

Evaluation of the Therapeutic Potential of a CNP Analog in a Fgfr3 Mouse Model Recapitulating Achondroplasia

(2012) Florence Lorget et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An activating Fgfr3 mutation affects trabecular bone formation via a paracrine mechanism during growth

(2012) Emilie Mugniery et al.   HUMAN MOLECULAR GENETICS

Muenke Syndrome Mutation, FgfR3P244R, Causes TMJ Defects

(2012) T. Yasuda et al.   JOURNAL OF DENTAL RESEARCH

Surgical Correction of Maxillofacial Skeletal Deformities

(2012) David A. Cottrell et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

(2011) Aurélie Jonquoy et al.   HUMAN MOLECULAR GENETICS

Craniofacial Growth in Patients With FGFR3Pro250Arg Mutation After Fronto-Orbital Advancement in Infancy

(2011) Emily B. Ridgway et al.   JOURNAL OF CRANIOFACIAL SURGERY

Ihh Signaling Regulates Mandibular Symphysis Development and Growth

(2011) H. Sugito et al.   JOURNAL OF DENTAL RESEARCH

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

(2011) Vito Guagnano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia

(2010) Stéphanie Pannier et al.   BONE

MorphoJ: an integrated software package for geometric morphometrics

(2010) CHRISTIAN PETER KLINGENBERG   Molecular Ecology Resources

Abnormal mandibular growth and the condylar cartilage

(2009) P. Pirttiniemi et al.   EUROPEAN JOURNAL OF ORTHODONTICS

Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence

(2009) Sabina Benko et al.   NATURE GENETICS

Achondroplasia

(2008) Geneviève Baujat et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia

(2008) Stéphanie Pannier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Roles of FGFR3 during morphogenesis of Meckel's cartilage and mandibular bones

(2008) Bruce A. Havens et al.   DEVELOPMENTAL BIOLOGY

FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway

(2008) T. Matsushita et al.   HUMAN MOLECULAR GENETICS