A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging

Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation

(2016) Stephanie M Matt et al.   CURRENT OPINION IN PHARMACOLOGY

Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?

(2016) Sinéad M. Ryan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Striatal Circuits as a Common Node for Autism Pathophysiology

(2016) Marc V. Fuccillo   Frontiers in Neuroscience

Creatine biosynthesis and transport in health and disease

(2015) Marie Joncquel-Chevalier Curt et al.   BIOCHIMIE

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

(2015) Elizabeth Head et al.   Current Alzheimer Research

Lysosomal dysfunction and impaired autophagy in a novel mouse model deficient for the lysosomal membrane protein Cln7

(2015) Laura Brandenstein et al.   HUMAN MOLECULAR GENETICS

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits

(2015) Federica Maccarinelli et al.   NEUROBIOLOGY OF DISEASE

The hippocampus in aging and disease: From plasticity to vulnerability

(2015) T. Bartsch et al.   NEUROSCIENCE

Molecular aspects of age-related cognitive decline: the role of GABA signaling

(2015) Joseph A. McQuail et al.   TRENDS IN MOLECULAR MEDICINE

Activity Dependency and Aging in the Regulation of Adult Neurogenesis

(2015) Gerd Kempermann   Cold Spring Harbor Perspectives in Biology

Microglial cell dysregulation in brain aging and neurodegeneration

(2015) Rommy von Bernhardi et al.   Frontiers in Aging Neuroscience

Functions and Dysfunctions of Adult Hippocampal Neurogenesis

(2014) Kimberly M. Christian et al.   Annual Review of Neuroscience

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

X-linked creatine transporter deficiency: clinical aspects and pathophysiology

(2014) Jiddeke M. van de Kamp et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Developmental studies of the hippocampus and hippocampal-dependent behaviors: Insights from interdisciplinary studies and tips for new investigators

(2014) Sarah H. Albani et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Homeostatic and injury-induced microglia behavior in the aging brain

(2013) Jasmin K. Hefendehl et al.   AGING CELL

Phenotype and genotype in 101 males with X-linked creatine transporter deficiency

(2013) J M van de Kamp et al.   JOURNAL OF MEDICAL GENETICS

Differential Balance of Prefrontal Synaptic Activity in Successful versus Unsuccessful Cognitive Aging

(2013) C. Bories et al.   JOURNAL OF NEUROSCIENCE

Lipofuscin: formation, effects and role of macroautophagy

(2013) Annika Höhn et al.   Redox Biology

Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

(2012) Matthew Kellom et al.   BMC NEUROSCIENCE

Inborn errors of creatine metabolism and epilepsy

(2012) Vincenzo Leuzzi et al.   EPILEPSIA

l-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome

(2012) Chi-un Choe et al.   HUMAN MOLECULAR GENETICS

Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake

(2012) C. I. Nabuurs et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neuroinflammation and Synaptic Loss

(2012) Jagadeesh S. Rao et al.   NEUROCHEMICAL RESEARCH

Creatine deficiency syndromes and the importance of creatine synthesis in the brain

(2011) Olivier Braissant et al.   AMINO ACIDS

Creatine as an antioxidant

(2011) Piero Sestili et al.   AMINO ACIDS

The creatine kinase system and pleiotropic effects of creatine

(2011) Theo Wallimann et al.   AMINO ACIDS

New neurons in an aged brain

(2011) Star W. Lee et al.   BEHAVIOURAL BRAIN RESEARCH

RETRACTED ARTICLE: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats

(2011) Jagadeesh Sridhara Rao et al.   Journal of Neuroinflammation

Ageing, Neuronal Connectivity and Brain Disorders: An Unsolved Ripple Effect

(2011) Daniele Bano et al.   MOLECULAR NEUROBIOLOGY

Creatine Transporter (CrT; Slc6a8) Knockout Mice as a Model of Human CrT Deficiency

(2011) Matthew R. Skelton et al.   PLoS One

Assessment of Social Interaction Behaviors

(2011) Oksana Kaidanovich-Beilin et al.   Jove-Journal of Visualized Experiments

Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging

(2010) Zeshan Ahmed et al.   AMERICAN JOURNAL OF PATHOLOGY

Early Environmental Enrichment Moderates the Behavioral and Synaptic Phenotype of MeCP2 Null Mice

(2010) Giuseppina Lonetti et al.   BIOLOGICAL PSYCHIATRY

Defining the pathogenicity of creatine deficiency syndrome

(2010) Patricia Alcaide et al.   HUMAN MUTATION

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

(2010) Dominic M. Ippolito et al.   Jove-Journal of Visualized Experiments

Oxidized proteins: Mechanisms of removal and consequences of accumulation

(2009) Rachael A. Dunlop et al.   IUBMB LIFE

Chronic green tea consumption prevents age-related changes in rat hippocampal formation

(2009) Marco Assunção et al.   NEUROBIOLOGY OF AGING

Immunohistochemical localisation of the creatine transporter in the rat brain

(2009) C.S.W. Mak et al.   NEUROSCIENCE

Mouse neurexin-1  deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

(2009) M. R. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR

Creatine improves health and survival of mice

(2007) A. Bender et al.   NEUROBIOLOGY OF AGING