Effects of the Bowen-Conradi syndrome mutation in EMG1 on its nuclear import, stability and nucleolar recruitment

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

(2016) Markus Kornprobst et al.   CELL

NSUN3 and ABH1 modify the wobble position of mt‐tRNAMetto expand codon recognition in mitochondrial translation

(2016) Sara Haag et al.   EMBO JOURNAL

Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

(2016) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

Growth arrest in the ribosomopathy, Bowen–Conradi syndrome, is due to dramatically reduced cell proliferation and a defect in mitotic progression

(2015) Joy Armistead et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension

(2015) Philipp Stelter et al.   MOLECULAR CELL

Mechanism of eIF6 release from the nascent 60S ribosomal subunit

(2015) Félix Weis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs

(2015) Sara Haag et al.   RNA

‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification

(2015) Sunny Sharma et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanism of eIF6 release from the nascent 60S ribosomal subunit

(2015) Félix Weis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells

(2015) Lukas Badertscher et al.   Cell Reports

The Dedicated Chaperone Acl4 Escorts Ribosomal Protein Rpl4 to Its Nuclear Pre-60S Assembly Site

(2015) Benjamin Pillet et al.   PLoS Genetics

The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus

(2015) John N. Griffin et al.   PLoS Genetics

Nucleolar stress in Diamond Blackfan anemia pathophysiology

(2014) Steven R. Ellis   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diverse diseases from a ubiquitous process: The ribosomopathy paradox

(2014) Joy Armistead et al.   FEBS LETTERS

Purification of protein complexes of defined subunit stoichiometry using a set of orthogonal, tag-cleaving proteases

(2014) Steffen Frey et al.   JOURNAL OF CHROMATOGRAPHY A

The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21

(2014) Katherine E. Sloan et al.   NUCLEIC ACIDS RESEARCH

The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA

(2014) K. E. Sloan et al.   RNA

WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N7-methylation of G1639 in human 18S rRNA

(2014) Sara Haag et al.   RNA

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

Human diseases of the SSU processome

(2013) Samuel B. Sondalle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing

(2013) Katherine E. Sloan et al.   JOURNAL OF CELL BIOLOGY

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

The evolution of the ribosome biogenesis pathway from a yeast perspective

(2013) Ingo Ebersberger et al.   NUCLEIC ACIDS RESEARCH

DExD/H-box RNA helicases in ribosome biogenesis

(2013) Roman Martin et al.   RNA Biology

Dysregulation of RNA polymerase I transcription during disease

(2012) K.M. Hannan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ribosome Biogenesis and Control of Cell Proliferation: p53 Is Not Alone

(2012) G. Donati et al.   CANCER RESEARCH

Synchronizing Nuclear Import of Ribosomal Proteins with Ribosome Assembly

(2012) D. Kressler et al.   SCIENCE

NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing

(2012) Emily F. Freed et al.   PLoS Genetics

Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

(2011) A. J. Finch et al.   GENES & DEVELOPMENT

Diamond Blackfan Anemia: Ribosomal Proteins Going Rogue

(2011) Steven R. Ellis et al.   SEMINARS IN HEMATOLOGY

The Role of p53 in Ribosomopathies

(2011) Stefano Fumagalli et al.   SEMINARS IN HEMATOLOGY

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

(2011) Nicholas J. Watkins et al.   Wiley Interdisciplinary Reviews-RNA

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

When ribosomes go bad: diseases of ribosome biogenesis

(2010) Emily F. Freed et al.   Molecular BioSystems

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

(2010) Seth R. Thomas et al.   NUCLEIC ACIDS RESEARCH

The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase

(2010) Jan Philip Wurm et al.   NUCLEIC ACIDS RESEARCH

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA

(2010) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

(2010) Thomas Wild et al.   PLOS BIOLOGY

Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome

(2009) Joy Armistead et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Novel Small-Subunit Processome Assembly Intermediate That Contains the U3 snoRNP, Nucleolin, RRP5, and DBP4

(2009) A. J. Turner et al.   MOLECULAR AND CELLULAR BIOLOGY

The Noc-Domain Containing C-Terminus of Noc4p Mediates Both Formation of the Noc4p-Nop14p Submodule and Its Incorporation into the SSU Processome

(2009) Holger Kühn et al.   PLoS One

The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site

(2008) A. B. Taylor et al.   NUCLEIC ACIDS RESEARCH