Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension

Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats

(2015) G.F. Bomfim et al.   LIFE SCIENCES

Pioglitazone reduces angiotensin II-induced COX-2 expression through inhibition of ROS production and ET-1 transcription in vascular cells from spontaneously hypertensive rats

(2014) Jose V. Pérez-Girón et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Impact of inflammation on vascular disease in hypertension

(2014) Agostino Virdis et al.   MATURITAS

Toll-Like Receptor 4 Upregulation by Angiotensin II Contributes to Hypertension and Vascular Dysfunction through Reactive Oxygen Species Production

(2014) Priscila R. De Batista et al.   PLoS One

Toll-like receptors and damage-associated molecular patterns: novel links between inflammation and hypertension

(2013) Cameron G. McCarthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4

(2013) Chao-Fan Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in l-NAME-induced hypertension

(2013) Daniel Sollinger et al.   CARDIOVASCULAR RESEARCH

Immune mechanisms in hypertension and vascular injury

(2013) Ernesto L. Schiffrin   CLINICAL SCIENCE

Toll-like Receptor Status in Obesity and Metabolic Syndrome: A Translational Perspective

(2013) Ishwarlal Jialal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Reciprocal Relationship Between Reactive Oxygen Species and Cyclooxygenase-2 and Vascular Dysfunction in Hypertension

(2012) Sonia Martínez-Revelles et al.   ANTIOXIDANTS & REDOX SIGNALING

From Skeleton to Cytoskeleton

(2012) Chi Yung Yuen et al.   CIRCULATION RESEARCH

Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats

(2012) Gisele F. Bomfim et al.   CLINICAL SCIENCE

HSP70 increases extracellular matrix production by human vascular smooth muscle through TGF-β1 up-regulation

(2012) Marta González-Ramos et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TLR2 and TLR4 Gene Expression in Peripheral Monocytes in Nondiabetic Hypertensive Patients: The Effect of Intensive Blood Pressure-Lowering

(2012) Maria E. Marketou et al.   Journal of Clinical Hypertension

Hypertension augments cardiac Toll-like receptor 4 expression and activity

(2011) Ruth Eißler et al.   HYPERTENSION RESEARCH

Structural abnormalities of small resistance arteries in essential hypertension

(2011) Damiano Rizzoni et al.   Internal and Emergency Medicine

Peroxisome proliferator-activated receptor-γ activation reduces cyclooxygenase-2 expression in vascular smooth muscle cells from hypertensive rats by interfering with oxidative stress

(2011) Angela Martín et al.   JOURNAL OF HYPERTENSION

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative Stress and Hypertension: Current Concepts

(2010) Ana M. Briones et al.   CURRENT HYPERTENSION REPORTS

Role of extracellular matrix in vascular remodeling of hypertension

(2010) Ana M Briones et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Toll like receptor 4 in atherosclerosis and plaque destabilization

(2009) Wijnand K. den Dekker et al.   ATHEROSCLEROSIS

Candesartan attenuates Angiotensin II-induced mesangial cell apoptosis via TLR4/MyD88 pathway

(2009) Jinlei Lv et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

(2009) Susan Carpenter et al.   BIOCHEMICAL JOURNAL

Angiotensin II Induces Inflammatory Response Partly Via Toll-Like Receptor 4-Dependent Signaling Pathway in Vascular Smooth Muscle Cells

(2009) Yuanyuan Ji et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Atorvastatin Prevents Angiotensin II–Induced Vascular Remodeling and Oxidative Stress

(2009) Ana M. Briones et al.   HYPERTENSION

Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

(2008) Thomas Münzel et al.   ANNALS OF MEDICINE

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

(2008) Paul C.Y. Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small artery remodelling in hypertension: causes, consequences and therapeutic implications

(2008) Michael J. Mulvany   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity

(2007) Jussi A. Hernesniemi et al.   ATHEROSCLEROSIS