A store-operated calcium channel inhibitor attenuates collagen-induced arthritis

Upregulation of store-operated Ca2+ entry in the naïve CD4+ T cells with aberrant cytokine releasing in active rheumatoid arthritis

(2014) Shuang Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis

(2014) Jingsheng Xia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Contribution of TRPC3 to Store-Operated Calcium Entry and Inflammatory Transductions in Primary Nociceptors

(2014) Hazim Alkhani et al.   Molecular Pain

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions

(2013) Gang Chen et al.   MOLECULAR IMMUNOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Potent analgesic effects of a store-operated calcium channel inhibitor

(2013) Ruby Gao et al.   PAIN

Gene Associated With Retinoid-Interferon-Induced Mortality 19 Attenuates Murine Autoimmune Arthritis by Regulation of Th17 and Treg Cells

(2013) Young-Mee Moon et al.   Arthritis & Rheumatology

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency

(2012) Duygu B. Bas et al.   ARTHRITIS AND RHEUMATISM

Review: Central pain mechanisms in the rheumatic diseases: Future directions

(2012) Kristine Phillips et al.   ARTHRITIS AND RHEUMATISM

Systematic Review of Tocilizumab for Rheumatoid Arthritis: A New Biologic Agent Targeting the Interleukin-6 Receptor

(2012) Iris Navarro-Millán et al.   CLINICAL THERAPEUTICS

Pain in Rheumatoid Arthritis

(2012) David A. Walsh et al.   Current Pain and Headache Reports

Calcium/calmodulin dependent kinase II contributes to persistent central neuropathic pain following spinal cord injury

(2012) Eric D. Crown et al.   PAIN

Effect and Treatment of Chronic Pain in Inflammatory Arthritis

(2012) Yvonne C. Lee   Current Rheumatology Reports

Suppression of collagen-induced arthritis in growth arrest and DNA damage-inducible protein 45β-deficient mice

(2011) Yubin Luo et al.   ARTHRITIS AND RHEUMATISM

Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets

(2011) Matthew T. Harper et al.   CELL CALCIUM

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2

(2011) Mankit Law et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Monosodium Iodoacetate-Induced Joint Pain is Associated with Increased Phosphorylation of Mitogen Activated Protein Kinases in the Rat Spinal Cord

(2011) Younglim Lee et al.   Molecular Pain

Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis

(2011) Aisha Siddiqah Ahmed et al.   PAIN

New Concepts in Pain Research and Pain Management of the Rheumatic Diseases

(2011) Don L. Goldenberg et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Central Sensitization in Patients with Rheumatoid Arthritis: A Systematic Literature Review

(2011) Mira Meeus et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

(2010) Jian Ma et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Store-Operated Ca2+ Entry through ORAI1 Is Critical for T Cell-Mediated Autoimmunity and Allograft Rejection

(2010) C.-A. McCarl et al.   JOURNAL OF IMMUNOLOGY

Trpm4 Differentially Regulates Th1 and Th2 Function by Altering Calcium Signaling and NFAT Localization

(2010) K. S. Weber et al.   JOURNAL OF IMMUNOLOGY

Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes

(2010) Mirko Voelkers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Chronic Conditions and Health Problems in Rheumatic Diseases: Comparisons with Rheumatoid Arthritis, Noninflammatory Rheumatic Disorders, Systemic Lupus Erythematosus, and Fibromyalgia

(2010) F. WOLFE et al.   JOURNAL OF RHEUMATOLOGY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Store-operated CRAC channels: function in health and disease

(2010) Anant B. Parekh   NATURE REVIEWS DRUG DISCOVERY

Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis

(2010) Christina A. Christianson et al.   PAIN

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond

(2009) Stefan Feske   IMMUNOLOGICAL REVIEWS

Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

(2009) A. Di Sabatino et al.   JOURNAL OF IMMUNOLOGY

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Experimental arthritis causes tumor necrosis factor-α-dependent infiltration of macrophages into rat dorsal root ganglia which correlates with pain-related behavior

(2009) Gisela Segond von Banchet et al.   PAIN

Effect of interleukin-1β on spinal cord nociceptive transmission of normal and monoarthritic rats after disruption of glial function

(2009) Luis Constandil et al.   ARTHRITIS RESEARCH & THERAPY

Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

(2008) Keiko Ohga et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Calcium signaling in immune cells

(2008) Monika Vig et al.   NATURE IMMUNOLOGY

The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

(2007) Keiko Ohga et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS