Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

ER Stress and Autophagy Dysfunction Contribute to Fatty Liver in Diabetic Mice

(2015) Quan Zhang et al.   International Journal of Biological Sciences

FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway

(2014) S. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation

(2014) Jaime L. Schneider et al.   Cell Metabolism

Pigment Epithelium-Derived Factor (PEDF) Suppresses IL-1β-Mediated c-Jun N-Terminal Kinase (JNK) Activation to Improve Hepatocyte Insulin Signaling

(2014) Arijeet K. Gattu et al.   ENDOCRINOLOGY

Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis

(2014) Shan Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids

(2013) Hongliang Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease

(2013) S Döcke et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: Cause or consequence?

(2013) C. García-Ruiz et al.   FREE RADICAL RESEARCH

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

Nonalcoholic Fatty Liver Disease: A Novel Cardiometabolic Risk Factor for Type 2 Diabetes and Its Complications

(2013) Giovanni Targher et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Independent Association between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: A Systematic Review and Meta-Analysis

(2013) Hongyun Lu et al.   International Journal of Endocrinology

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Mapping Autophagy on to Your Metabolic Radar

(2012) E. Yamada et al.   DIABETES

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

Lipid-Induced Endoplasmic Reticulum Stress in Liver Cells Results in Two Distinct Outcomes: Adaptation with Enhanced Insulin Signaling or Insulin Resistance

(2012) Caroline S. Achard et al.   ENDOCRINOLOGY

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

(2012) Yingfeng Deng et al.   JOURNAL OF CLINICAL INVESTIGATION

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

(2012) Santhosh Satapati et al.   JOURNAL OF LIPID RESEARCH

Amino acids and mTORC1: from lysosomes to disease

(2012) Alejo Efeyan et al.   TRENDS IN MOLECULAR MEDICINE

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

Fatty acid distribution of cord and maternal blood in human pregnancy: special focus on individual trans fatty acids and conjugated linoleic acids

(2011) Uta Enke et al.   Lipids in Health and Disease

Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals

(2010) Patricia Iozzo et al.   GASTROENTEROLOGY

Altered Autophagy in Human Adipose Tissues in Obesity

(2010) Julia Kovsan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase

(2009) B. D. Hegarty et al.   Acta Physiologica

Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion

(2009) Srinivasan Dasarathy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

From Sugar to Fat

(2009) Laurie H. Glimcher et al.   Annals of the New York Academy of Sciences

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Comparison of Lipid and Fatty Acid Composition of the Liver, Subcutaneous and Intra-abdominal Adipose Tissue, and Serum

(2009) Anna Kotronen et al.   Obesity

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

(2008) M. F. Gregor et al.   DIABETES

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice

(2008) Qiong Wang et al.   HEPATOLOGY

Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease

(2008) Nobito Higuchi et al.   HEPATOLOGY RESEARCH

AMPK: a key regulator of energy balance in the single cell and the whole organism

(2008) D G Hardie   INTERNATIONAL JOURNAL OF OBESITY

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE