Liver progenitor cells-mediated liver regeneration in liver cirrhosis

Hepatic inflammation and fibrosis: Functional links and key pathways

(2015) Ekihiro Seki et al.   HEPATOLOGY

Hepatocytes, Rather than Cholangiocytes, Can Be the Major Source of Primitive Ductules in the Chronically Injured Mouse Liver

(2014) Sayaka Sekiya et al.   AMERICAN JOURNAL OF PATHOLOGY

Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

(2014) Kilangsungla Yanger et al.   Cell Stem Cell

Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes

(2014) Branden D. Tarlow et al.   Cell Stem Cell

Clonal tracing of Sox9+liver progenitors in mouse oval cell injury

(2014) Branden D. Tarlow et al.   HEPATOLOGY

The biliary epithelium gives rise to liver progenitor cells

(2014) Daniel Rodrigo-Torres et al.   HEPATOLOGY

Sry HMG Box Protein 9-positive (Sox9+) Epithelial Cell Adhesion Molecule-negative (EpCAM−) Biphenotypic Cells Derived from Hepatocytes Are Involved in Mouse Liver Regeneration

(2014) Naoki Tanimizu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic stellate cells contribute to progenitor cells and liver regeneration

(2014) Claus Kordes et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic progenitor cells in liver regeneration: current advances and clinical perspectives

(2014) Aezam Katoonizadeh et al.   LIVER INTERNATIONAL

Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury

(2014) Johanna R. Schaub et al.   Cell Reports

Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation

(2013) Kaori Kuramitsu et al.   AMERICAN JOURNAL OF PATHOLOGY

Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion

(2013) Michael J. Williams et al.   GASTROENTEROLOGY

FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration

(2013) H. M. Takase et al.   GENES & DEVELOPMENT

Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy

(2013) M Swiderska-Syn et al.   GUT

Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells in mice

(2013) Dan Li et al.   HEPATOLOGY

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

(2013) Jean-Philippe Pradere et al.   HEPATOLOGY

Role of TWEAK in coregulating liver progenitor cell and fibrogenic responses

(2013) Janina E.E. Tirnitz-Parker et al.   HEPATOLOGY

Liver regeneration by stem/progenitor cells

(2013) Tohru Itoh et al.   HEPATOLOGY

Macrophage plasticity and polarization in liver homeostasis and pathology

(2013) Antonio Sica et al.   HEPATOLOGY

Hepatic stem cell niches

(2013) Claus Kordes et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

(2013) Meritxell Huch et al.   NATURE

Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling

(2013) T. G. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration

(2012) Nian-Ling Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-2 Spectrin is involved in hepatocyte proliferation through the interaction of TGFβ/Smad and PI3K/AKT signalling

(2012) Zhijun Wang et al.   LIVER INTERNATIONAL

TWEAK/Fn14 promotes the proliferation and collagen synthesis of rat cardiac fibroblasts via the NF-кB pathway

(2012) Hui-Na Chen et al.   MOLECULAR BIOLOGY REPORTS

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

Oval Cell Response Is Attenuated by Depletion of Liver Resident Macrophages in the 2-AAF/Partial Hepatectomy Rat

(2012) Shuai Xiang et al.   PLoS One

Kupffer Cells Influence Parenchymal Invasion and Phenotypic Orientation, but Not the Proliferation, of Liver Progenitor Cells in a Murine Model of Liver Injury

(2011) Noémi Van Hul et al.   AMERICAN JOURNAL OF PATHOLOGY

Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice

(2011) C. Dorrell et al.   GENES & DEVELOPMENT

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

(2011) James A. Thomas et al.   HEPATOLOGY

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Hepatocyte growth factor/c-metsignaling is required for stem-cell-mediated liver regeneration in mice

(2011) Tsuyoshi Ishikawa et al.   HEPATOLOGY

Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis

(2011) Zhijun Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

(2011) Yann Malato et al.   JOURNAL OF CLINICAL INVESTIGATION

Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats

(2011) Marie-Noële Chobert et al.   LABORATORY INVESTIGATION

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response

(2010) Y. N. Kallis et al.   GUT

Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver

(2010) S. Lorenzini et al.   GUT

Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates

(2010) Yunfang Wang et al.   HEPATOLOGY

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells

(2010) Janina E. E. Tirnitz-Parker et al.   HEPATOLOGY

Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury

(2010) Cornelia S. Viebahn et al.   JOURNAL OF HEPATOLOGY

Hepatic stellate cells’ involvement in progenitor-mediated liver regeneration

(2010) Dana G Pintilie et al.   LABORATORY INVESTIGATION

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Stem Cells and Liver Regeneration

(2009) Andrew W. Duncan et al.   GASTROENTEROLOGY

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

(2009) B. Spee et al.   GUT

Role of transforming growth factor β signaling and expansion of progenitor cells in regenerating liver

(2009) Arun Thenappan et al.   HEPATOLOGY

Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury

(2009) Noémi K. M. Van Hul et al.   HEPATOLOGY

Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells

(2008) Nan Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The hepatic stem cell niche: Identification by label-retaining cell assay

(2008) Reiichiro Kuwahara et al.   HEPATOLOGY

Lymphotoxin-β receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury

(2008) Richard G. Ruddell et al.   HEPATOLOGY

Hepatic stellate cells modulate the differentiation of bone marrow mesenchymal stem cells into hepatocyte-like cells

(2008) Xing Deng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fate-Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers

(2008) Liu Yang et al.   STEM CELLS