CD4+Foxp3+T cells promote aberrant immunoglobulin G production and maintain CD8+T-cell suppression during chronic liver disease

Regulatory T cells turn pathogenic

(2015) Jitao Guo et al.   Cellular & Molecular Immunology

Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development

(2015) Victoria M. Velazquez et al.   HEPATOLOGY

Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity

(2015) Manoj Thapa et al.   HEPATOLOGY

CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study

(2015) Anthony Shock et al.   ARTHRITIS RESEARCH & THERAPY

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

IgG Subclasses and Allotypes: From Structure to Effector Functions

(2014) Gestur Vidarsson et al.   Frontiers in Immunology

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory T-cell directed therapies in liver diseases

(2013) Ye Htun Oo et al.   JOURNAL OF HEPATOLOGY

Hepatic Stellate Cells Preferentially Induce Foxp3+ Regulatory T Cells by Production of Retinoic Acid

(2013) R. M. Dunham et al.   JOURNAL OF IMMUNOLOGY

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice

(2012) Leonhard Stross et al.   HEPATOLOGY

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Hepatic Stellate Cells Function as Regulatory Bystanders

(2011) S. Ichikawa et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

(2010) Madhav D. Sharma et al.   IMMUNITY

Anti-CD40L Immune Complexes Potently Activate Platelets In Vitro and Cause Thrombosis in FCGR2A Transgenic Mice

(2010) L. Robles-Carrillo et al.   JOURNAL OF IMMUNOLOGY

PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

(2010) Kim L Good-Jacobson et al.   NATURE IMMUNOLOGY

CD46-induced human Treg enhance B-cell responses

(2009) Anja Fuchs et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV

(2009) Debora Franceschini et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune-mediated liver injury

(2009) Ansgar W. Lohse et al.   JOURNAL OF HEPATOLOGY

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

(2009) Mark A.A. Claassen et al.   JOURNAL OF HEPATOLOGY