From NAFLD to HCC: Is IL-17 the crucial link?

Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma

(2016) Ana L. Gomes et al.   CANCER CELL

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

(2016) Chi Ma et al.   NATURE

Immunology in the liver — from homeostasis to disease

(2016) Felix Heymann et al.   Nature Reviews Gastroenterology & Hepatology

IL-17 Axis Driven Inflammation in Non-Alcoholic Fatty Liver Disease Progression

(2015) Daniel Giles et al.   CURRENT DRUG TARGETS

Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver

(2015) Monika Rau et al.   JOURNAL OF IMMUNOLOGY

Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes

(2014) Monika Julia Wolf et al.   CANCER CELL

IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice

(2013) Isaac T.W. Harley et al.   HEPATOLOGY

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

(2012) Fanli Meng et al.   GASTROENTEROLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Role of IL-17 and Th17 Cells in Liver Diseases

(2010) Linda Hammerich et al.   Clinical & Developmental Immunology