The Importance of Toll-like Receptors in NF-κB Signaling Pathway Activation byHelicobacter pyloriInfection and the Regulators of this Response

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Toll-like receptors: Activation, signalling and transcriptional modulation

(2015) Dominic De Nardo   CYTOKINE

Kyoto global consensus report onHelicobacter pylorigastritis

(2015) Kentaro Sugano et al.   GUT

Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population

(2015) Fu-bing Tang et al.   INFECTION GENETICS AND EVOLUTION

Polymorphisms in TLR9 but not in TLR5 increase the risk for duodenal ulcer and alter cytokine expression in the gastric mucosa

(2015) Alejandra Trejo-de la O et al.   Innate Immunity

Toll-like Receptor 10 inHelicobacter pyloriInfection

(2015) Hiroyuki Nagashima et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 trial

(2015) Ming Zeng et al.   LANCET

Interplay of the Gastric PathogenHelicobacter pyloriwith Toll-Like Receptors

(2015) Suneesh Kumar Pachathundikandi et al.   Biomed Research International

Effect of the −2081G/A Polymorphism of the TLR4 Gene and Its Interaction with Helicobacter pylori Infection on the Risk of Gastric Cancer in Chinese Individuals

(2014) Ping Li et al.   Genetic Testing and Molecular Biomarkers

Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer

(2014) Natalia Castaño-Rodríguez et al.   HUMAN IMMUNOLOGY

MiR-146a Negatively Regulates TLR2-Induced Inflammatory Responses in Keratinocytes

(2014) Florian Meisgen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TLR9 and NF-κB Are Partially Involved in Activation of Human Neutrophils by Helicobacter pylori and Its Purified DNA

(2014) Lourdes Alvarez-Arellano et al.   PLoS One

Novel role of toll-like receptors inHelicobacter pylori- induced gastric malignancy

(2014) Kaname Uno   WORLD JOURNAL OF GASTROENTEROLOGY

Structural modifications ofHelicobacter pylorilipopolysaccharide: An idea for how to live in peace

(2014) Magdalena Chmiela   WORLD JOURNAL OF GASTROENTEROLOGY

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production

(2013) Hao Zhou et al.   EMBO JOURNAL

Toll-Like Receptors and Cytokines are Upregulated duringHelicobacter pyloriInfection in Children

(2013) Hugo Lagunes-Servin et al.   HELICOBACTER

TLR4 polymorphisms associated with developing gastric pre-cancer lesions in a Chinese Han population

(2013) Yao-fu Fan et al.   HUMAN IMMUNOLOGY

Study of TLR4 and IL-8 Gene Polymorphisms inH.pylori-Induced Inflammation in Gastric Cancer in an Ethnic Kashmiri Population

(2013) Qurteeba Qadri et al.   IMMUNOLOGICAL INVESTIGATIONS

Identification of Genetic Loci Associated With Helicobacter pylori Serologic Status

(2013) Julia Mayerle et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Let-7b Is Involved in the Inflammation and Immune Responses Associated with Helicobacter pylori Infection by Targeting Toll-Like Receptor 4

(2013) Gui-gen Teng et al.   PLoS One

TLR2 Mediates Helicobacter pylori–Induced Tolerogenic Immune Response in Mice

(2013) Xia Sun et al.   PLoS One

Toll-like receptor 9 signaling has anti-inflammatory effects on the early phase of Helicobacter pylori-induced gastritis

(2012) Koji Otani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Management ofHelicobacter pyloriinfection—the Maastricht IV/ Florence Consensus Report

(2012) Peter Malfertheiner et al.   GUT

A Frequent Toll-Like Receptor 1 Gene Polymorphism Affects NK- and T-cell IFN-γ Production and is Associated withHelicobacter pylori-induced Gastric Disease

(2012) Chin-An Yang et al.   HELICOBACTER

Helicobacter pyloriInduces Increased Expression of Toll-Like Receptors and Decreased Toll-Interacting Protein in Gastric Mucosa that Persists Throughout Gastric Carcinogenesis

(2012) Pedro Pimentel-Nunes et al.   HELICOBACTER

Role of theHelicobacter pylori-Induced inflammatory response in the development of gastric cancer

(2012) Acacia Lamb et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Integrin CD11b Negatively Regulates TLR9-Triggered Dendritic Cell Cross-Priming by Upregulating microRNA-146a

(2012) Y. Bai et al.   JOURNAL OF IMMUNOLOGY

Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212

(2012) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-7–regulated TLR9 signaling–enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway

(2012) Lin Xu et al.   MOLECULAR BIOLOGY OF THE CELL

MicroRNA-574-5p Was Pivotal for TLR9 Signaling Enhanced Tumor Progression via Down-Regulating Checkpoint Suppressor 1 in Human Lung Cancer

(2012) Qinchuan Li et al.   PLoS One

Chimeric flagellin as the self-adjuvanting antigen for the activation of immune response against Helicobacter pylori

(2012) Jerneja Mori et al.   VACCINE

Polymorphisms of theTLR2andTLR4genes are associated with risk of gastric cancer in a Brazilian population

(2012) Juliana Garcia de Oliveira   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic Variants of Toll-Like Receptor 2 and 5, Helicobacter Pylori Infection, and Risk of Gastric Cancer and Its Precursors in a Chinese Population

(2011) H.-M. Zeng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Epidemiology of Helicobacter pylori Infection and Public Health Implications

(2011) Khean-Lee Goh et al.   HELICOBACTER

Tribbles 3: A Novel Regulator of TLR2-Mediated Signaling in Response to Helicobacter pylori Lipopolysaccharide

(2011) S. M. Smith et al.   JOURNAL OF IMMUNOLOGY

NF-κB is 25

(2011) David Baltimore   NATURE IMMUNOLOGY

Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α

(2011) Suneesh Kumar Pachathundikandi et al.   PLoS One

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

(2010) L. E. Wroblewski et al.   CLINICAL MICROBIOLOGY REVIEWS

No associations of Toll-like receptor 2 (TLR2) -196 to -174del polymorphism with the risk of Helicobacter pylori seropositivity, gastric atrophy, and gastric cancer in Japanese

(2010) Asahi Hishida et al.   Gastric Cancer

Genetic modulation of TLR8 response following bacterial phagocytosis

(2010) Michael P. Gantier et al.   HUMAN MUTATION

MicroRNA signatures in Helicobacter pylori-infected gastric mucosa

(2010) Kayoko Matsushima et al.   INTERNATIONAL JOURNAL OF CANCER

Flanking region sequence information to refine microRNA target predictions

(2010) Russiachand Heikham et al.   JOURNAL OF BIOSCIENCES

Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling

(2010) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pyloriInfection

(2010) Kenneth E.L. McColl   NEW ENGLAND JOURNAL OF MEDICINE

CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations

(2009) Georgina L. Hold et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Extracellular and Intracellular Pattern Recognition Receptors Cooperate in the Recognition of Helicobacter pylori

(2009) Roland Rad et al.   GASTROENTEROLOGY

Helicobacter pyloriVacA Activates NF-κB in T Cells via the Classical but not Alternative Pathway

(2009) Eriko Takeshima et al.   HELICOBACTER

Toll-Like Receptor 4 +3725 G/C Polymorphism,Helicobacter pyloriSeropositivity, and the Risk of Gastric Atrophy and Gastric Cancer in Japanese

(2009) Asahi Hishida et al.   HELICOBACTER

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

Increase in NF- B Binding Affinity of the Variant C Allele of the Toll-Like Receptor 9 -1237T/C Polymorphism Is Associated with Helicobacter pylori-Induced Gastric Disease

(2009) M. T. H. Ng et al.   INFECTION AND IMMUNITY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Modulation of TLR2 Protein Expression by miR-105 in Human Oral Keratinocytes

(2009) Manjunatha R. Benakanakere et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial DNA Activates Endothelial Cells and Promotes Neutrophil Adherence through TLR9 Signaling

(2009) D. El Kebir et al.   JOURNAL OF IMMUNOLOGY

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

TLR4 single-nucleotide polymorphisms alter mucosal cytokine and chemokine patterns in Mexican patients with Helicobacter pylori-associated gastroduodenal diseases

(2008) Alejandra Trejo-de la O et al.   CLINICAL IMMUNOLOGY

Toll-like receptor (TLR2, TLR4 and TLR5) gene polymorphisms and Helicobacter pylori infection in children with and without duodenal ulcer

(2008) Sílvia Beleza Moura et al.   MICROBES AND INFECTION

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

mRNA levels of TLR4 and TLR5 are independent of H pylori

(2008) Elvira Garza-González et al.   WORLD JOURNAL OF GASTROENTEROLOGY