Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis

Growth Hormone Releasing Hormone in Endothelial Barrier Function

(2021) Nektarios Barabutis   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of lung endothelial permeability by NEK kinases

(2020) Nektarios Barabutis   IUBMB LIFE

Control of clathrin-mediated endocytosis by NIMA family kinases

(2020) Braveen B. Joseph et al.   PLoS Genetics

GHRH Antagonists Protect Against Hydrogen Peroxide-Induced Breakdown of Brain Microvascular Endothelium Integrity

(2020) Nektarios Barabutis et al.   HORMONE AND METABOLIC RESEARCH

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7

(2020) Laura O'Regan et al.   JOURNAL OF CELL SCIENCE

Cytokine Storms: Understanding COVID-19

(2020) Nilam Mangalmurti et al.   IMMUNITY

NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

(2020) Nasir Haider et al.   ONCOGENE

NEK7 Coordinates Rapid Neuroinflammation After Subarachnoid Hemorrhage in Mice

(2020) Gen Li et al.   Frontiers in Neurology

P53 in acute respiratory distress syndrome

(2020) Nektarios Barabutis   CELLULAR AND MOLECULAR LIFE SCIENCES

The Molecular and Pathophysiological Functions of Members of the LNX/PDZRN E3 Ubiquitin Ligase Family

(2020) Jeongkwan Hong et al.   MOLECULES

Physiological and Pathological Roles of Mammalian NEK7

(2020) Zhenzhen Sun et al.   Frontiers in Physiology

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

(2020) Ellen Gorman et al.   Expert Review of Respiratory Medicine

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

P53: The endothelium defender

(2019) Mohammad Afaz Uddin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

VHL regulates NEK1 via both HIF-2α pathway and ubiquitin-proteasome pathway in renal cancer cell

(2019) Guang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

(2019) Bert van de Kooij et al.   eLife

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

(2019) Humayun Sharif et al.   NATURE

EK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury

(2019) Yuhua Chen et al.   Frontiers in Molecular Neuroscience

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

Wild-type p53 enhances endothelial barrier function by mediating RAC1 signalling and RhoA inhibition

(2018) Nektarios Barabutis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma

(2018) Reinaldo Franqui-Machin et al.   JOURNAL OF CLINICAL INVESTIGATION

Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42-SID-3/ACK1 pathway

(2018) Vladimir Lažetić et al.   PLoS Genetics

Hsp90 inhibitors suppress P53 phosphorylation in LPS - induced endothelial inflammation

(2018) Nektarios Barabutis et al.   CYTOKINE

Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression

(2017) Sheng-Ming Wu et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of pulmonary endothelial barrier function by kinases

(2016) Nektarios Barabutis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Delayed Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis*

(2016) Joshua A. Smith et al.   CRITICAL CARE MEDICINE

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

Claudin Heterogeneity and Control of Lung Tight Junctions

(2012) Michael Koval   Annual Review of Physiology

Aurora B kinase phosphorylates and instigates degradation of p53

(2012) C. P. Gully et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential effects of claudin-3 and claudin-4 on alveolar epithelial barrier function

(2011) Leslie A. Mitchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cultured Alveolar Epithelial Cells From Septic Rats Mimic In Vivo Septic Lung

(2010) Taylor S. Cohen et al.   PLoS One

Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP

(2009) Yifeng Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA