4.7 Editorial Material

P53 in acute respiratory distress syndrome

Journal

CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 77, Issue 22, Pages 4725-4727

Publisher

SPRINGER BASEL AG
DOI: 10.1007/s00018-020-03629-1

Keywords

Inflammation; Acute lung injury; Unfolded protein response; Heat shock proteins

Funding

  1. R&D, Research Competitiveness Subprogram (RCS) of the Louisiana Board of Regents through the Board of Regents Support Fund [LEQSF(2019-22)-RD-A-26]
  2. FRSP award of the College of Pharmacy (ULM)
  3. National Institute of General Medical Sciences of the National Institutes of Health [5 P20 GM103424-15, 3 P20 GM103424-15S1]

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P53 is a tumor suppressor protein, associated with strong anti-inflammatory activities. Recent evidence suggest that this transcription factor counteracts lung inflammatory diseases, including the lethal acute respiratory distress syndrome. Herein we provide a brief discussion on the relevant topic.

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