Article
Dermatology
Sheila C. Barbarino, Julie A. Woodward, Jennifer Levine, John Fezza
Summary: The study involved 10 women aged 42-74 years with moderate-to-severe lateral periorbital lines (LPL) and perioral lines at rest. At 1 month, treating physician GAIS scores indicated 45.0% of subjects were very much improved and 52.5% much improved; 75% remained at least improved at 6 months. Subject GAIS results indicated 7 women rated themselves as very much improved and 3 as much improved.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yuanshan Liu, Xingzhu Liu, Yajie Zhang, Yi Cao, Bingqing Luo, Zheng Wang, Renjun Pei
Summary: This paper presents an interpenetrating polymer network (IPN) hydrogel that mimics the interactions between cells and extracellular matrix (ECM) in a three-dimensional (3D) environment. By combining physical and chemical cross-linking networks, the hydrogel maintains mechanical stability and facilitates cell adhesion. It also demonstrates the feasibility of using gelatin sacrificial solution for 3D printing within the hydrogel matrix, allowing the fabrication of vascularized microfluidic channels. The results highlight the efficacy of this IPN hydrogel system in supporting 3D cell growth and emphasize the potential of 3D printed constructs for vascularization in tissue engineering.
Article
Nanoscience & Nanotechnology
Hatai Jongprasitkul, Vijay Singh Parihar, Sanna Turunen, Minna Kellomaki
Summary: The challenges of poor printability and low printing accuracy in hyaluronic acid-based bioinks for extrusion-based 3D bioprinting are tackled by developing a bioink consisting of gallic acid-functionalized hyaluronic acid (HAGA) and hyaluronic acid methacrylate (HAMA). The blend's HAGA component enables viscosity modulation, resulting in improved injectability and printability. Postprinting, the HAMA component is photocrosslinked to create a hydrogel with both HAGA and HAMA networks, showing sufficient printing quality and accuracy. The bioink also has enhanced viscoelastic properties, tissue adhesion, and antioxidant activity.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Editorial Material
Surgery
Ivar van Heijningen
Summary: Based on this article, it can be concluded that HA fillers are an effective treatment for tear troughs. A comprehensive analysis of the face, particularly the peri-orbital area, is crucial in selecting suitable candidates for this treatment. A thorough understanding of anatomy is essential in this selection process and to prevent potential complications.
AESTHETIC PLASTIC SURGERY
(2022)
Article
Pharmacology & Pharmacy
Aiden Eblimit, Mustafa S. Makia, Daniel Strayve, Ryan Crane, Shannon M. Conley, Tirthankar Sinha, Ghanashyam Acharya, Muayyad R. Al-Ubaidi, Muna I. Naash
Summary: The study aimed to evaluate two innovative approaches to increase the persistence and penetration of nanospheres into the outer retina with less invasive intravitreal delivery method. The findings demonstrated that co-delivery of sulfotyrosine and HA-NS significantly improved the penetration of nanospheres into the retina and accumulation along the interface between photoreceptors and retinal pigment epithelium.
Article
Orthopedics
Luisa de Roy, Kerstin Eichhorn, Martin Faschingbauer, Klaus Schlickenrieder, Anita Ignatius, Andreas Martin Seitz
Summary: The purpose of this in vitro study was to investigate the effect of hyaluronic acid supplementation on knee joint friction during osteoarthritis progression. The results showed that knee joint friction does not increase with degeneration, and hyaluronic acid supplementation does not lead to an initial decrease in friction.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Agriculture, Dairy & Animal Science
Savannah R. Gregg, Madison R. Barshick, Sally E. Johnson
Summary: The study found that injection of hyaluronic acid can have anti-inflammatory effects without disrupting the normal muscle repair process after exercise.
Article
Surgery
Hyun-Jin Shin, Shin-Hyo Lee, Jung-Ah Park, Ki-Seok Koh, Wu-Chul Song
Summary: This study dissected cadaver orbits to determine the arterial distribution, revealing a relatively safe zone for filler injections to avoid major vessel injury. The detailed topographic information provided may help reduce the risk of retrobulbar hemorrhage and vision-threatening complications.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Chemistry, Physical
Ke Ren, Hongping Wan, Hans J. Kaper, Prashant K. Sharma
Summary: In this study, hyaluronic acid (HA) was conjugated with dopamine to form HADN, which exhibited adhesive properties while retaining viscosity enhancement capacity. It was found that HADN could enhance cartilage lubrication through adsorption onto collagen, providing better protection for cartilage compared to HA alone.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Rheumatology
Chien-Chih Wang, Chin-Tien Wang, Kun-Ling Tsai, Chen-Liang Chou, Jian-Kang Chao, Hsin-Yi Huang, Chung-Lan Kao
Summary: The study showed that increased suprapatellar effusion detected by ultrasound may predict reduced efficacy of HA injection in treating knee OA.
Article
Anatomy & Morphology
Kyu-Ho Yi, Wook Oh, Hyoung Moon Kim, Hyo-Sang Ahn, Hyewon Hu, Hee-Jin Kim
Summary: A subzygomatic arch depression can cause a bulky face outline. Hyaluronic acid filler injection methods are commonly used to smooth out these depressions and correct facial contours. However, the complexity of the subzygomatic region makes it challenging for practitioners to effectively volumize the area.
Article
Dermatology
Hayson Chenyu Wang, Yunting Wang, Xiao Long, Xiaojun Wang
Summary: Mandibular osteomyelitis after filler injection is extremely rare, and strict measures to minimize contamination and infection risk are essential. Clinicians should consider the possibility of osteomyelitis if the patient presents with incurable mandibular infection post-filler injection.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Pharmacology & Pharmacy
Min-Hwan Kim, Ju-Hwan Park, Duy-Thuc Nguyen, Sungyun Kim, Da In Jeong, Hyun-Jong Cho, Dae-Duk Kim
Summary: An HAase inhibitor-incorporated hyaluronic acid hydrogel was designed to reduce toxicity risk and slow biodegradation rate in subcutaneous tissue. The hydrogel, formulated with Quercetin as an HAase inhibitor and quetiapine as a model drug, exhibited sustained drug release and improved pharmacokinetic parameters in rats following subcutaneous injection. All results supported the designed hydrogel as a biocompatible formulation for sustained drug delivery.
Article
Pharmacology & Pharmacy
Nouran O. Eladawy, Nadia M. Morsi, Rehab N. Shamma
Summary: This study optimized the formulation of intra-articular injectable hyaluronic acid gel-core vesicles loaded with diacerein (DCN) through a full factorial design, achieving high entrapment efficiency and small particle size. The prepared DCN-loaded hyaluosomes showed superior function in preventing cartilage damage and inflammation in rats with induced arthritis, demonstrating their potential as a novel intra-articular injection for osteoarthritis management.
Article
Pharmacology & Pharmacy
Andrea Bernetti, Francesco Agostini, Federica Alviti, Nicola Giordan, Federica Martella, Valter Santilli, Marco Paoloni, Massimiliano Mangone
Summary: The study demonstrates that a single intra-articular injection of the new HA derivative hydrogel, Hymovis MO.RE., provides significant efficacy and safety in improving knee function, pain, and quality of life for adult regular sports players with osteoarthritis. No severe adverse events were detected, indicating it may be a viable therapeutic option for this patient subgroup. Further investigations are needed to confirm these findings.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Dermatology
Joseph N. Mehrabi, Efrat Bar-Ilan, Shehadeh Wasim, Amir Koren, Lior Zusmanovitch, Fares Salameh, Gila Isman Nelkenbaum, Tamir Horovitz, Eyal Zur, Ting Song Lim, Jacob Mashiah, Ofir Artzi
Summary: This article reviews different energy-based combination treatments for melasma, aiming to address stubborn and recurring cases by combining devices with medications. Treatment algorithms proposed in the article target various components of melasma for improved outcomes.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Arisa Kaewkes, Woraphong Manuskiatti, Kathryn Anne Cembrano, Rungsima Wanitphakdeedecha
Summary: The study evaluated the long-term efficacy and safety of a fractional 1064-nm picosecond laser for treating striae alba in dark-skinned individuals. The results showed significant improvement in skin texture and melanin index, with 90% of subjects demonstrating moderate to marked improvement in striae appearance. Furthermore, only a low incidence of transient postinflammatory hyperpigmentation was observed, indicating that the laser treatment is effective and well-tolerated.
LASERS IN SURGERY AND MEDICINE
(2022)
Article
Dermatology
Pakagamon Tumsutti, Mart Maiprasert, Pansak Sugkraroek, Rungsima Wanitphakdeedecha, Akkarach Bumrungpert
Summary: The study demonstrates that supplementation with a blend of Glycine max, Cimicifuga racemosa, Vitex agnus-castus, and Oenothera biennis extracts is beneficial for skin health and antioxidant status in women after menopause.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Tingsong Lim, Konstantin Frank, Basste Hadjab
Summary: Injectable rejuvenation treatments may not be universally suitable for all ethnicities due to variations in aging patterns. The Target-Specific Sandwich Technique (TSST) presented in this study offers a customized approach for Asian patients, utilizing different fillers with varying rheologies to achieve facial rejuvenation and enhancement. Patients undergoing the TSST reported improved facial features and overall satisfaction with the treatment outcome.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Petchlada Achavanuntakul, Woraphong Manuskiatti, Rungsima Wanitphakdeedecha, Tatre Jantarakolica
Summary: Initiating laser treatment for Nevus of Ota before the age of 5 significantly improves therapeutic outcomes, reduces the risk of adverse events and recurrence in patients.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
(2022)
Article
Dermatology
Woraphong Manuskiatti, Chadakan Yan, Ofir Artzi, Mia Katrina R. Gervasio, Rungsima Wanitphakdeedecha
Summary: The study compared the efficacy and safety of thermomechanical fractional injury (TMFI)-assisted topical corticosteroid delivery with corticosteroid injection in the treatment of hypertrophic scar (HTS). Results showed that TMFI-assisted topical corticosteroid delivery is an effective treatment for HTS with a lower risk of adverse effects compared to corticosteroid injection.
LASERS IN SURGERY AND MEDICINE
(2022)
Article
Dermatology
Chadakan Yan, Janice Natasha C. Ng, Rungsima Wanitphakdeedecha
Summary: This study evaluated the efficacy and safety of a handheld iontophoresis device in enhancing transdermal vitamin C delivery. The results showed significant improvement in pore tightening and skin hydration in the group using iontophoresis compared to baseline. No adverse reactions were recorded.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Tatre Jantarakolica, Rungsima Wanitphakdeedecha, Chadakan Yan, Janice Natasha C. Ng, Tatchalerm Sudhipongpracha
Summary: This study aims to explore the factors determining the treatment price of port-wine stain (PWS). The study found that treatment by dermatologists and treatment with different laser types can significantly affect the cost of PWS treatment. The location and type of medical facility also play a role in determining the treatment price.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Carla de Sanctis Pecora, Karin Ventura Ferreira, Helio Amante Miot
Summary: This study demonstrates the effectiveness of the ONE21 technique in assessing and treating facial wrinkles and muscle contractions in identical twins. Using personalized evaluations, the ONE21 technique allows for an objective assessment of upper face wrinkles, even in identical twins.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Ma Christina B. Gulfan, Rungsima Wanitphakdeedecha, Supisara Wongdama, Nuttagarn Jantanapornchai, Chadakan Yan, Sarawalai Rakchart
Summary: This study investigated the efficacy and safety of using a microneedling radiofrequency device with polynucleotides versus radiofrequency alone for the treatment of melasma. The results showed that both treatments significantly improved the symptoms of melasma, with no significant differences between the two. Microneedling radiofrequency treatment was found to be safe and effective in improving skin roughness and can be used as an adjunctive treatment option for melasma.
DERMATOLOGY AND THERAPY
(2022)
Article
Dermatology
Niamh Corduff, Lanny Juniarti, Ting Song Lim, Frank Lin, Kavita Mariwalla, Tatjana Pavicic, Arnelle Quiambao, Tuck Wah Siew, Atchima Suwanchinda, Fang Wen Tseng, Vasanop Vachiramon, Choon Shik Youn, Wilson W. S. Ho
Summary: Complications such as delayed inflammatory reactions and unnatural outcomes can arise from HA dermal filler treatments. Preventive strategies, including appropriate filler selection, aseptic technique, and patient selection, can reduce the risk of complications. Achieving natural-looking outcomes requires customized treatment, understanding different filler properties, and a conservative treatment approach.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2022)
Article
Dermatology
Awika Rongthong, Rungsima Wanitphakdeedecha, Mart Maiprasert, Kathryn Anne Guico Cembrano, Nataya Voravutinon, Sarawalai Rakchart, Kanchana Sermswan, Pongsiri Koonngam
Summary: This study evaluated the efficacy and safety of hyaluronic acid (HA) fillers for the treatment of horizontal neck lines using a blunt cannula injection technique. The results showed that the HA filler injection improved the appearance of neck lines, with peak improvement at 1 month and sustained rejuvenation effects up to 6 months after treatment.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Martin Agren, Yanisorn Nanchaipruek, Phumithep Phumariyapong, Chalermkwan Apinuntham, Sarawalai Rakchart, Mattias Pettersson, Rungsima Wanitphakdeedecha
Summary: This study aims to evaluate the duration of reduced maximal voluntary bite force (MVBF) after botulinum toxin intervention. The results showed that MVBF in the intervention group significantly decreased at 3 months but returned to baseline levels after 6 months.
JOURNAL OF ORAL REHABILITATION
(2023)
Article
Surgery
Windie Hayano, Martina Kerscher, Doris Day, Alexandra Ogilvie, Tatjana Pavicic, Tingsong Lim, Paul Z. Lorenc, Claudia Hernandez, Konstantin Frank, Nicholas Moellhoff, Valentina Prinz, Cajkovsky Mia, Rainer Pooth, Jeremy Green
Summary: This study successfully created and validated two 5-point photonumeric scales for assessing perioral lines and marionette lines.
AESTHETIC SURGERY JOURNAL
(2023)
Article
Dermatology
Tatre Jantarakolica, Rungsima Wanitphakdeedecha, Chadakan Yan, Yuri Yogya, Woraphong Manuskiatti, Tatchalerm Sudhipongpracha
Summary: This study investigates the quality of life and treatment outcomes of patients with port-wine stains (PWS), finding that PWS significantly impairs the quality of life of both patients and parents. Age and treatment method were identified as influencing factors.
DERMATOLOGY AND THERAPY
(2023)