Article
Biochemistry & Molecular Biology
Maria Jesus Ruiz-Alvarez, Emanuela Stampone, Yaiza Fernandez Verduras, Giovanni Gallo, Marta Barrionuevo Gonzalez, Belen Betere Cubillo, Debora Bencivenga, Fulvio Della Ragione, Adriana Borriello
Summary: Hypocalcemia is found to be a significant factor associated with worsened condition, mechanical ventilation requirement, and poor prognosis in COVID-19 patients. Moreover, hypocalcemia is also correlated with comorbidities such as cardiovascular diseases, chronic kidney disease, and cancer, as well as clinical complications during hospitalization.
BIOMEDICAL JOURNAL
(2023)
Review
Psychiatry
Mirella Russo, Dario Calisi, Matteo A. De Rosa, Giacomo Evangelista, Stefano Consoli, Fedele Dono, Matteo Santilli, Francesco Gambi, Marco Onofrj, Massimo Di Giannantonio, Giustino Parruti, Stefano L. Sensi
Summary: SARS-CoV-2 can enter the central nervous system and trigger neurological syndromes during and after COVID-19. It is also found to potentially cause mood disorders or psychotic symptoms. However, there is limited analysis on first episodes of mania in individuals with no known history of bipolar disorder associated with COVID-19.
PSYCHIATRY RESEARCH
(2022)
Review
Infectious Diseases
Mikaela Smit, Annalisa Marinosci, Thomas Agoritsas, Alexandra Calmy
Summary: This study systematically reviewed prophylactic candidates for COVID-19 and found that HCQ seems to have no prophylactic effect, while the effectiveness of other candidates remains unclear, with many ongoing RCTs.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Endocrinology & Metabolism
Luigi di Filippo, Mauro Doga, Stefano Frara, Andrea Giustina
Summary: COVID-19 patients may experience various endocrine manifestations, such as hypocalcemia, vertebral fractures, and vitamin D deficiency, which could negatively impact disease severity, inflammatory response, thrombotic markers, and mortality. Prompt assessment, monitoring, and calcium replacement are recommended to prevent severe complications.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2022)
Review
Nutrition & Dietetics
Marcelino Perez-Bermejo, Belen Peris-Ochando, Maria Teresa Murillo-Llorente
Summary: Research suggests that breastfeeding by mothers infected with SARS-CoV-2 is highly recommended for infants if both the mother and the infant are in good health, while encouraging appropriate protective measures. If direct breastfeeding is not suitable due to the mother's health condition, pumping milk or using donor milk for feeding infants is advised.
Review
Pathology
Stefania Caramaschi, Meghan E. Kapp, Sara E. Miller, Rosana Eisenberg, Joyce Johnson, Garretson Epperly, Antonino Maiorana, Guido Silvestri, Giovanna A. Giannico
Summary: Pathological findings from autopsy and biopsy studies of COVID-19 patients reveal main features of diffuse alveolar damage, thromboembolism, and nonspecific shock injury in multiple organs. Additionally, it suggests a unifying pathogenic mechanism for COVID-19 as ARDS with inflammatory response, cytokine release, fever, inflammation, and generalized endothelial disturbance.
Review
Virology
Marcos Jesse Abrahao Silva, Layana Rufino Ribeiro, Maria Isabel Montoril Gouveia, Beatriz dos Reis Marcelino, Carolynne Silva dos Santos, Karla Valeria Batista Lima, Luana Nepomuceno Gondim Costa Lima
Summary: This research aimed to review the immunopathological elements that contribute to the progression of COVID-19. A systematic review was conducted using various databases and search terms. The study identified several key factors, such as SARS-CoV-2 spike proteins, cellular proteases, leukocytes, cytokines, and proteolytic cascades, that play a role in the hyperinflammatory response and subsequent complications. It is important to control the dysregulation of the immune response and systemic inflammation for patients' recovery.
Article
Multidisciplinary Sciences
Muluneh Alene, Leltework Yismaw, Moges Agazhe Assemie, Daniel Bekele Ketema, Belayneh Mengist, Bekalu Kassie, Tilahun Yemanu Birhan
Summary: Asymptomatic SARS-CoV-2 infections are responsible for potentially significant transmission of COVID-19. A systematic review and meta-analysis of 28 studies with 6,071 cases found that the weighted pooled proportion of asymptomatic COVID-19 cases throughout the course of infection was 25%, suggesting the importance of scaling up testing for high risk populations to control the pandemic.
Review
Cardiac & Cardiovascular Systems
Fatemeh Omidi, Bahareh Hajikhani, Seyyedeh Neda Kazemi, Ardeshir Tajbakhsh, Sajedeh Riazi, Mehdi Mirsaeidi, Ali Ansari, Masoud Ghanbari Boroujeni, Farima Khalili, Sara Hadadi, Mohammad Javad Nasiri
Summary: The study found that cardiac complications are common in patients with COVID-19, mainly manifested as cardiomyopathy. It is recommended to consider the possibility of cardiac damage in the management of these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Biology
Salem Garfan, A. H. Alamoodi, B. B. Zaidan, Mohammed Al-Zobbi, Rula A. Hamid, Jwan K. Alwan, Ibraheem Y. Y. Ahmaro, Eman Thabet Khalid, F. M. Jumaah, O. S. Albahri, A. A. Zaidan, A. S. Albahri, Z. T. Al-qaysi, M. A. Ahmed, Moceheb Lazam Shuwandy, Mahmood M. Salih, Omar Zughoul, K. Mohammed, Fayiz Momani
Summary: During the COVID-19 pandemic, telehealth has been widely utilized due to its usability and safety in providing healthcare services. However, there are still challenges hindering the maximisation of telehealth, which requires further research and solutions.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Review
Chemistry, Analytical
Renata Maia, Violeta Carvalho, Bernardo Faria, Ines Miranda, Susana Catarino, Senhorinha Teixeira, Rui Lima, Graca Minas, Joao Ribeiro
Summary: This study provides an overview of COVID-19 diagnosis methods and tests as well as their evolution in recent months. While RT-PCR remains the gold-standard method, it is limited by equipment and personnel requirements as well as the time to obtain results. As a result, alternative methods have been commonly reported. Combining different diagnostic techniques helps improve diagnosis and further understand the impact of the virus and the disease on humans.
Review
Immunology
Weijing Shang, Yaping Wang, Jie Yuan, Zirui Guo, Jue Liu, Min Liu
Summary: This study assessed the global excess mortality during the COVID-19 pandemic. The results showed that the global excess mortality rate was 104.84 deaths per 100,000, and the reported all-cause deaths were higher than expected deaths. South America, developing and middle-income countries, male populations, and individuals aged >= 60 years had a heavier burden of excess mortality.
Review
Immunology
Chan-Young Kwon, Boram Lee
Summary: This systematic review investigated the potential impact of COVID-19 vaccinations on human heart rate variability (HRV) parameters. The findings revealed short-term changes and rapid recovery in HRV parameters, particularly the square root of the mean squared differences of successive NN intervals (RMSSD), following COVID-19 vaccination. Some studies showed that the impact of COVID-19 vaccinations on HRV parameters was greater in women and younger individuals.
Review
Biochemistry & Molecular Biology
Ziyaana Kabani, Maria E. Ramos-Nino, Prakash V. A. K. Ramdass
Summary: This review aimed to estimate the prevalence of SARS-CoV-2 infection and the health impacts of the COVID-19 pandemic in endometriosis patients. The analysis showed that the prevalence of SARS-CoV-2 infection in endometriosis patients was 7.5%. Additionally, the pandemic caused a worsening of symptoms such as dysmenorrhea, pelvic pain, anxiety, depression, and fatigue.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Immunology
Amir Bahador Boroumand, Mahtab Forouhi, Farzaneh Karimi, Arman Soltani Moghadam, Leila Ghanbari Naeini, Pajman Kokabian, Delaram Naderi
Summary: Immunogenicity of COVID-19 vaccines is generally lower in patients with diabetes mellitus compared to healthy individuals. Age, type of diabetes, BMI, glycemic control, and eGFR are factors that affect antibody response.
FRONTIERS IN IMMUNOLOGY
(2022)
Correction
Immunology
Shahin Merat, Amir-Houshang Sharifi, Hossein Poustchi, Eskandar Hajiani, Abdolsamad Gharavi, Jalal Karimi, Fariborz Mansour-Ghanaei, Mohammad-Reza Fattahi, Lida Ahmadi, Mohammad-Hossein Somi, Hamid Kalantari, Mohammad-Reza Ghadir, Farshad Sheikhesmaeili, Nadieh Baniasadi, Masoudreza Sohrabi, Seyedhamid Moosavy, Masood Ziaee, Mohammad-Javad Zahedi, Marjan Mokhtare, Shahnaz Sali, Babak Sayad, Behrooz Afshar, Alireza Bakhshipour, Abazar Parsi, Afsaneh Sharifian, Taghi Amiriani, Zeinab Malekzadeh, Dorsa Merat, Azita Ganji, Fereidoun Rahmani-Samani, Raika Jamali, Masoomeh Sofian, Mohammad Ghezlou, Amir Ali Sohrabpour, Ladan Goshayeshi, Seyed-Mohammad Valizadeh-Toosi, Layli Eslami, Iradj Maleki, Ahmad Hormati, Ali-Akbar Shayesteh, Elahe Shayesteh, Alireza Norouzi, Zahra Abna, Alireza Janbakhsh, Hafez Fakheri, Mohammad Minakari, Hossein Sardarian, Adel F. Allah Ghajary, Mojtaba Fattahi-Abdizadeh, Maryam Latifnia, Fatemeh Roozbeh, Shahram Agah, Saba Fakhrieh-Asl, Alireza Nateghi-Baygi, Babak Fattahi, Helia Nateghi-Baygi, Andrew Hill, Reza Malekzadeh
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Pharmacology & Pharmacy
Elahehnaz Parhizkar, Parivash Rafieipour, Alireza Sepasian, Effat Alemzadeh, Ali Dehshahri, Fatemeh Ahmadi
Summary: Gemcitabine, a nucleoside analogue drug, has limitations due to rapid body clearance, but chemical conjugation with Tobacco Mosaic Virus shows potential for drug delivery with minimal toxicity. In vitro studies suggest improved cytotoxicity and drug release from the conjugate, indicating potential for better pharmacokinetics and reduced toxicity in vivo.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Infectious Diseases
Zohreh Fattahi, Marzieh Mohseni, Khadijeh Jalalvand, Fatemeh Aghakhani Moghadam, Azam Ghaziasadi, Fatemeh Keshavarzi, Jila Yavarian, Ali Jafarpour, Seyedeh Elham Mortazavi, Fatemeh Ghodratpour, Hanieh Behravan, Mohammad Khazeni, Seyed Amir Momeni, Issa Jahanzad, Abdolvahab Moradi, Alijan Tabarraei, Sadegh Ali Azimi, Ebrahim Kord, Seyed Mohammad Hashemi-Shahri, Azarakhsh Azaran, Farid Yousefi, Zakiye Mokhames, Alireza Soleimani, Shokouh Ghafari, Masood Ziaee, Shahram Habibzadeh, Farhad Jeddi, Azar Hadadi, Alireza Abdollahi, Gholam Abbas Kaydani, Saber Soltani, Talat Mokhtari-Azad, Reza Najafipour, Reza Malekzadeh, Kimia Kahrizi, Seyed Mohammad Jazayeri, Hossein Najmabadi
Summary: This study provided 50 whole-genome sequences of SARS-CoV-2 viral isolates from different geographical locations in Iran during March-July 2020. Analysis revealed at least two introductions of the virus into the country, leading to the dominance of B.4 lineage in the early epidemic followed by an increase in frequency of D614G mutation and B.1* lineages from mid-May onwards, indicating a rapid viral transmission that could lead to drastic changes in the circulating viral lineages in the country.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Microbiology
Neda Mahavar, Mohsen Naseri, Gholamreza Anani Sarab, Mohammad Fereidouni, Masood Ziaee, Hamidreza Safari, Mohammad Sadegh Naghizadeh, Abdolghader Tane, Roya Mahdavi
Summary: The study revealed an association between IL-10-1082 polymorphisms, particularly the GG genotype, and the clearance of HBV infection, as well as a reduced risk of chronic hepatitis B infection. However, there was no significant difference in IL-10-1082 A/G alleles between the two study groups.
JUNDISHAPUR JOURNAL OF MICROBIOLOGY
(2021)
Article
Medicine, General & Internal
Freshteh Osmani, Masood Ziaee
Summary: The case-control study in Birjand revealed a higher prevalence of vitamin D-3 deficiency among patients with chronic hepatitis B compared to healthy individuals, with a significantly increased risk of deficiency. Further research is needed to investigate the impact of vitamin D supplementation on chronic hepatitis B.
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
(2021)
Review
Cell Biology
Ahmad Oryan, Effat Alemzadeh, Esmat Alemzadeh, Maryam Barghi, Mohammad Zarei, Hamid Salehiniya
Summary: Adipose stem cell therapy can enhance the healing rate of burn wounds, especially when combined with hydrogels to significantly increase the viability of adipose stem cells. However, more clinical studies are needed to further explore the role of adipose stem cells in burn wound healing.
CELL AND TISSUE BANKING
(2022)
Article
Infectious Diseases
Sara Mobarak, Mehdi Salasi, Ahmad Hormati, Javad Khodadadi, Masood Ziaee, Farshid Abedi, Azadeh Ebrahimzadeh, Zohreh Azarkar, Fariborz Mansour-Ghanaei, Farahnaz Joukar, Sara Yeganeh, Tofigh Yaghubi Kalurazi, Mohammadreza Naghipour, Zeinab Mehrabi, Amir Reza Bahadori, Shoeleh Yaghoubi, Rohollah Moslemi, Hamideh Abbaspour Kasgari, Hafez Fakheri, Minoo Moghimi, Amir Mohammad Shabani, Zahra Nekoukar, Farhang Babamahmoodi, Ali Reza Davoudi Badabi, Lotfollah Davoodi, Mehdi Hassaniazad, Elham Barahimi, Abdolali Tousi, Anahita Sadeghi, Hadiseh Hosamirudsari, Ali Ali Asgari, Mohammad Abdollahi, Amir Anushiravani, Minoosh Shabani, Shervin Shokouhi, Nasim Khajavirad, Mohammadreza Salehi, Seyed Ali Dehghan Manshadi, Hashem Mousavi, Farnaz Zolfaghari, Elmira Azimi, Aida Zeinali, Elham Akbarpour, Dorsa Merat, Gholamali Eslami, Sajedeh Mousaviasl, Sara Sayar, Esmat Radmanesh, Mona Ebrahimzadeh, Zahra Arizavi, Saeed Jelvay, Shokrollah Salmanzadeh, Hani Esmaeilian, Morteza Mobarak, Jalal Karimi, Zahra Poormontaseri, Nasrollah Hasooni Bahrini, Atefeh Bonyadi, Fatemeh Dehghani, Hadi Mirzaei, Masoome Noori Jangi, Hossein Pourmasoomi, Lili Rezaie Keikhaie, Mahdi Afshari, Alireza Nateghi Baygi, Helia Nateghi Baygi, Jacob Levi, Kaitlyn McCann, Hannah Wentzel, Bryony Simmons, Andrew Hill, Shahin Merat
Summary: This study found that there was no significant effect of sofosbuvir/daclatasvir versus placebo on hospital discharge or survival in hospitalized COVID-19 patients.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Parasitology
Effat Alemzadeh, Mehdi Karamian, Farshid Abedi, Mohammad Yahya Hanafi-Bojd
Summary: This study synthesized silver nanoparticles from Artemisia aucheri leaf extract and examined their effects on leishmaniasis and antibacterial activity. The results showed that the ointment containing quercetin/artemisia-capped silver nanoparticles could promote wound healing and reduce inflammatory responses.
Review
Medicine, Research & Experimental
Afrooz Mazidimoradi, Esmat Alemzadeh, Effat Alemzadeh, Hamid Salehiniya
Summary: This study investigates the effect of polyunsaturated fatty acids on the prognosis of Covid-19. The findings suggest that Ω-3 supplements can reduce the risk of Covid-19, but elevated levels of fatty acids in the lungs and cytokine storm may be the main reasons for mortality in severe cases.
Article
Immunology
Masood Ziaee, Mohammad Amin Ghatee, Walter Robert Taylor, Mehdi Karamian
Summary: This study describes a family cluster of L. major infection, where the family members traveled to an endemic area and were treated differently, with two patients being hospitalized due to disease progression. Genotyping of the parasite gene revealed that the infecting strain was the same as one found in a tourist who visited North African countries. It is hypothesized that the host immune response may have been reduced in the hospitalized patients.
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Freshteh Osmani, Masood Ziaee
Summary: This study aimed to investigate the survival time of Covid-19 patients, considering frailty factor. The results showed that age and platelet count were negatively associated with the length of stay, while red blood cell count was positively associated with the length of stay. The study also found that frailty factor is a useful predictor of survival in Covid-19 patients.
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
(2022)
Article
Medicine, General & Internal
Zohreh Fattahi, Marzieh Mohseni, Maryam Beheshtian, Ali Jafarpour, Khadijeh Jalalvand, Fatemeh Keshavarzi, Hanieh Behravan, Fatemeh Ghodratpour, Farzane Zare Ashrafi, Marzieh Kalhor, Maryam Azad, Mahdieh Koshki, Azam Ghaziasadi, Mohamad Soveyzi, Alireza Abdollahi, Seyed Jalal Kiani, Angila Ataei-Pirkooh, Iman Rezaeiazhar, Farah Bokharaei-Salim, Mohammad Reza Haghshenas, Farhang Babamahmoodi, Zakiye Mokhames, Alireza Soleimani, Zohreh Elahi, Masood Ziaee, Davod Javanmard, Shokouh Ghafari, Akram Ezani, Alireza Ansari Moghaddam, Fariba Shahraki-Sanavi, Seyed Mohammad Hashemi Shahri, Azarakhsh Azaran, Farid Yousefi, Afagh Moattari, Mohsen Moghadami, Hamed Fakhim, Behrooz Ataei, Elahe Nasri, Vahdat Poortahmasebi, Mojtaba Varshochi, Ali Mojtahedi, Farid Jalilian, Mohammad Khazeni, Abdolvahab Moradi, Alijan Tabarraei, Ahmad Piroozmand, Yousef Yahyapour, Masoumeh Bayani, Fatemeh Tavangar, Mahmood Yaghoubi, Fariba Keramat, Mahsa Tavakoli, Tahmineh Jalali, Mohammad Hassan Pouriayevali, Mostafa Salehi-Vaziri, Hamid Reza Khorram Khorshid, Reza Najafipour, Reza Malekzadeh, Kimia Kahrizi, Seyed Mohammad Jazayeri, Hossein Najmabadi
Summary: This study provides a real-time and comprehensive picture of the SARS-CoV-2 genetic diversity in Iran, shedding light on the transmission and circulation of the virus in the region.
ARCHIVES OF IRANIAN MEDICINE
(2022)
Article
Microbiology
Abdol Sattar Pagheh, Arghavan Asghari, Khadijeh Abrari Romenjan, Tahoora Mousavi, Farshid Abedi, Arash Ziaee, Hakime Malakimoghadam, Masood Ziaee
Summary: This study evaluated the seroprevalence of SARS-CoV-2 in a random sample of healthcare workers at a large acute care hospital in Iran. Results showed that 24.4% of the healthcare workers were seropositive for anti-SARS-CoV-2 IgG. Males had a higher percentage of IgG positivity than females. There were significant associations between the presence of antibodies and occupation, location, and infecting family members with COVID-1.
IRANIAN JOURNAL OF MICROBIOLOGY
(2022)
Article
Medicine, Research & Experimental
Arash Ziaee, Ghodsiyeh Azarkar, Masood Ziaee
Summary: The study indicates a higher prevalence of pre-existing fatty liver among COVID-19 patients, who tend to have more severe disease and longer hospitalization periods than non-COVID-19 patients.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2021)
