Article
Neurosciences
Yan Liu, Han Xu, Naima Dahir, Ashley Calder, Fangjun Lin, Timothy A. Gilbertson
Summary: Recent studies have identified a new receptor, GPR84, in the gustatory system that responds to medium-chain saturated fatty acids (MCFAs) in male mice. Activation of GPR84 by MCFAs leads to depolarization and an increase in intracellular free calcium in taste cells. Knockout mouse models lacking GPR84 show specific deficits in neural and behavioral responses to oral MCFAs compared to wild-type mice.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Nutrition & Dietetics
Junhui Shen, Li Zhang, Yuanqi Wang, Zhiqing Chen, Jian Ma, Xiaoyun Fang, Undurti N. Das, Ke Yao
Summary: This study investigates the effects of ALA and LA on the metabolism, gut microbiota, and inflammatory and retinal indices in T1DM animals. The results show that ALA and LA have significant benefits in reversing the changes seen in T1DM, suggesting their importance in diabetes mellitus.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
A. Nikolai von Krusenstiern, Ryan N. Robson, Naixin Qian, Baiyu Qiu, Fanghao Hu, Eduard Reznik, Nailah Smith, Fereshteh Zandkarimi, Verna M. Estes, Marcel Dupont, Tal Hirschhorn, Mikhail S. Shchepinov, Wei Min, K. A. Woerpel, Brent R. Stockwell
Summary: Lipid peroxidation in subcellular membranes, especially the endoplasmic reticulum (ER) membrane, plays a crucial role in iron-dependent cell death called ferroptosis. Understanding the sequence and sites of membrane peroxidation will contribute to the development of targeted therapies for drug-resistant cancers and degenerative diseases.
NATURE CHEMICAL BIOLOGY
(2023)
Review
Food Science & Technology
Siddhant Dubey, Chiu-Wen Chen, Anil Kumar Patel, Shashi Kant Bhatia, Reeta Rani Singhania, Cheng-Di Dong
Summary: This review summarizes the research advancements in microalgae PUFA production and discusses the potential applications. Various cultivation modes, including heterotrophic, mixotrophic, and photoheterotrophic, are assessed for cost-effective PUFA production. Parameters such as salinity, nutrients, carbon source, and light intensity have significant effects on PUFA accumulation.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Biochemistry & Molecular Biology
Nirajan Shrestha, Nathan Rout-Pitt, Alexandra McCarron, Courtney A. A. Jackson, Andrew C. C. Bulmer, Andrew J. J. McAinch, Martin Donnelley, David W. W. Parsons, Deanne H. H. Hryciw
Summary: This study aimed to investigate the characteristics of essential fatty acid deficiency caused by cystic fibrosis (CF), which is the result of mutations in the CF transmembrane conductance regulator (CFTR). Two rodent models of CF were studied: one strain with a loss of phenylalanine at position 508 (Phe508del) in CFTR and the other lacking functional CFTR (510X). Fatty acid concentrations were measured in the serum, and the expression of genes related to fatty acid transport and metabolism was quantified. Histological assessment of the ileal tissue was also performed. The results showed genotype- and age-dependent alterations in fatty acid concentration, as well as changes in gene expression and tissue morphology. These findings suggest that CF rat models exhibit abnormalities in the handling of fatty acids, possibly due to altered transport and metabolism, as well as fibrosis and structural changes in the ileum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Tahar Hajri, Douglas Ewing, Toghrul Talishinskiy, Erica Amianda, Sebastian Eid, Hans Schmidt
Summary: The study showed that n-3 fatty acids were significantly reduced in patients with obesity after RYGB. Supplementation with DHA in PBMC can modulate the production of inflammation markers.
JOURNAL OF NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Julia P. Holen, Jason C. Woodworth, Mike D. Tokach, Robert D. Goodband, Joel M. DeRouchey, Jordan T. Gebhardt
Summary: Providing lactation diets with added fat sources that provide high essential fatty acids to sows prior to farrowing alters the composition of fatty acids in colostrum, milk, and body fat stores. However, changes in colostrum and milk composition did not influence litter growth performance.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Ecology
Hung Duc Pham, Minh-Hoang Le, Khuong V. Dinh, Muhammad A. B. Siddik, Do-Huu Hoang, Manh Van Ngo
Summary: A feeding factorial experiment was conducted to investigate the combined effects of selenium and highly unsaturated fatty acids (HUFA) on growth performance, fatty acid composition, skeletal deformities, and stress resistance of barramundi larvae. The results showed that enriching Artemia with selenium improved the growth and stress resistance of the larvae. Selenium supplementation also increased the levels of HUFA and DHA in the larvae.
REGIONAL STUDIES IN MARINE SCIENCE
(2022)
Article
Nutrition & Dietetics
Sanne Sigh, Lotte Lauritzen, Frank T. Wieringa, Arnaud Laillou, Chhoun Chamnan, Ken D. Stark, Nanna Roos
Summary: This study aimed to investigate the change in whole-blood PUFA levels and nutrition and health markers among Cambodian children with severe acute malnutrition (SAM) after treatment with ready-to-use therapeutic foods (RUTFs). Results showed that RUTFs with fish-based ingredients had higher levels of n-3 PUFA, AA, and DHA, while milk-based RUTFs had higher levels of n-6 PUFA. The study found that the currently recommended composition of RUTFs may not be able to correct the compromised essential fatty acid status of children with SAM. Rating: 8/10
CLINICAL NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Naoki Kabeya, Kazunori Kimura, Yoshiyuki Matsushita, Satoshi Suzuki, Yasuhiro Nagakura, Ryuhei Kinami, Hiroyuki Noda, Koji Takagi, Kazutoshi Okamoto, Misako Miwa, Yutaka Haga, Shuichi Satoh, Goro Yoshizaki
Summary: This study investigated the requirements of long-chain polyunsaturated fatty acids (LC-PUFAs) in the commercially important alfonsino fish, Beryx splendens. The results showed that B. splendens obtains substantial amounts of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from its natural diet. The study also confirmed the enzymatic capabilities of fatty acid desaturase (Fads2) and elongases (Elovl5, Elovl4a, and Elovl4b) in LC-PUFA biosynthesis in B. splendens.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Review
Nutrition & Dietetics
Rouzha Zlatanova Pancheva, Silviya Nikolova, Asena Serbezova, Krassimira Zaykova, Desislava Zhelyazkova, Lubomir Dimitrov
Summary: This review investigates the current evidence regarding the use of essential fatty acids (EFAs) in the treatment of autism spectrum disorders (ASDs) and explores the potential mechanisms and limitations of EFAs in ASDs. The results suggest that although some studies show a positive effect of EFAs on ASD symptoms, there is currently insufficient quantitative support.
FRONTIERS IN NUTRITION
(2023)
Article
Agronomy
Monika Nutautaite, Vilma Viliene, Asta Raceviciute-Stupeliene, Saulius Bliznikas, Jurate Karosiene, Judita Koreiviene
Summary: The study focused on evaluating the potential utilization of freshwater Cladophora glomerata as an alternative source of protein and essential nutrients in animal feed by conducting chemical analysis on samples collected from Lithuanian rivers. The results showed that Cladophora glomerata could serve as a beneficial alternative component of animal feed due to its rich protein content and essential amino acids profile.
Review
Biodiversity Conservation
Ana M. M. Goncalves, Carolina P. Rocha, Joao C. Marques, Fernando J. M. Goncalves
Summary: The toxic effects of pesticides, especially in aquatic ecosystems, have been a major concern for environmental and human safety. Biomarkers, such as antioxidant enzymes and fatty acids, are crucial in assessing the impacts of pesticides on organisms. Fatty acids have been identified as potential biomarkers due to their sensitivity to alterations in organism homeostasis, particularly in freshwater communities.
ECOLOGICAL INDICATORS
(2021)
Review
Biochemistry & Molecular Biology
Igori Balta, Lavinia Stef, Ioan Pet, Tiberiu Iancu, Ducu Stef, Nicolae Corcionivoschi
Summary: Cardiovascular diseases have become a leading cause of global mortality due to the impact of modern lifestyles on essential fatty acid consumption. Scientific research has focused on the cardio-protective role of certain fatty acids, such as PUFA and omega 3 fatty acids, in preventing heart disorders and associated risk factors.
Article
Engineering, Marine
Alexander Kasumyan, Olga Isaeva, Le T. K. Oanh
Summary: This study examined the taste attractiveness of 21 amino acids and 4 taste substances for barramundi, and investigated their feeding behavior. The results showed that citric acid, cysteine, and alanine were palatable, while sucrose and 7 amino acids had an aversive taste. Barramundi often made repeated grasps and rejections of pellets, leading to the destruction of the pellets.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Fisheries
Fletcher Warren-Myers, Stephen E. Swearer, David S. Francis, Giovanni M. Turchini, Kathy Overton, Tim Dempster
Summary: The study tested three types of dried algal supplements on the color, taste, and gonad quality of temperate urchins, finding that while all feed types resulted in commercially acceptable gonad production, the algal supplements did not improve gonad color, taste, or the proportion of marketable gonads compared to the control feed.
Editorial Material
Fisheries
Umberto Luzzana, Giovanni M. Turchini
REVIEWS IN AQUACULTURE
(2022)
Article
Immunology
Shilin Wang, Zhihao Han, Giovanni M. Turchini, Xiaoyuan Wang, Zishuo Fang, Naisong Chen, Ruitao Xie, Haitao Zhang, Songlin Li
Summary: This study demonstrated the specific requirement of dietary phospholipids for larval largemouth bass, and provided novel insights on how dietary phospholipids supplementation contributes to improving growth performance, digestive tract development, and intestinal health.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Engineering, Environmental
Nesar Ahmed, John Hornbuckle, Giovanni M. Turchini
Summary: Integrated rice-fish culture is an alternative method to rice monoculture that improves food productivity and environmental sustainability. Water management is a key challenge for the wider adoption of rice-fish cultivation, and the efficient utilization of blue and green water can help overcome water scarcity and increase water productivity.
Article
Fisheries
Ece Evliyaoglu, Serdar Kilercioglu, Hatice Asuman Yilmaz, Giovanni M. Turchini, Marina Paolucci, Timothy D. Clark, Ibrahim Demirkale, Orhan Tufan Eroldogan
Summary: This study evaluated the effects of iron supplementation in plant-based aquafeed on the growth performances, feed intake, nutrients, digestibility, iron-related serum parameters, and gene expression in juvenile rainbow trout. The results showed that adding 150 mg/kg feed of iron (equivalent to ~270 mg/kg feed total) can improve the growth performances and feed utilization in rainbow trout.
Review
Fisheries
Houguo Xu, Xiaoxue Meng, Yuliang Wei, Qiang Ma, Mengqing Liang, Giovanni M. Turchini
Summary: The importance of dietary arachidonic acid (ARA) in fish nutrition has been overlooked in the past, but recent studies have revealed its important functions in various physiological processes. These functions are influenced by factors such as dosage, species, development stage, sex, and feeding period.
REVIEWS IN AQUACULTURE
(2022)
Article
Fisheries
Thomas S. Mock, Zakarya H. R. A. A. Alkhabbaz, Melissa M. Rocker, Michael J. Lewis, Erin E. Cumming, Richard P. Smullen, Giovanni M. Turchini, David S. Francis
Summary: This study explored the influence of water temperature on the gut transit rate of ingested feed in Atlantic salmon. The results showed that temperature significantly affected the transit rate in the stomach and large intestine, but had little impact on the pyloric caeca and small intestine. These findings can be used to improve dietary strategies for commercially important fish species, ultimately enhancing nutrient utilization.
AQUACULTURE RESEARCH
(2022)
Article
Fisheries
Camila Fernandes Correa, Renata Oselame Nobrega, Bruna Mattioni, Giovanni M. Turchini, Debora Machado Fracalossi
Summary: This study evaluated the effects of different lipid sources on the in vivo fatty acid metabolism in Nile tilapia, and found that the enzyme activities and fatty acid composition were significantly affected by the diets and environmental temperatures.
Article
Fisheries
Abdul Lathiff Inamul Hassan, Thomas S. Mock, Kieren Searle, Melissa M. Rocker, Giovanni M. Turchini, David S. Francis
Summary: Australian abalone aquaculture is characterized by a prolonged culture period and slow and variable growth. Water temperature is a crucial factor influencing abalone's physiology and energetics, leading to changes in their nutritional requirements. Feeds are generally formulated based on the nutritional requirements at the optimal temperature, but there is a need to optimize dietary protein levels to match temperature-specific requirements during extreme conditions.
AQUACULTURE RESEARCH
(2023)
Article
Environmental Sciences
Lindsey Woolley, Md Reaz Chaklader, Luke Pilmer, Frances Stephens, Catherine Wingate, Michael Salini, Gavin Partridge
Summary: Methanotrophic bacteria can convert methane into highly nutritious single-cell protein (SCP), which can replace fishmeal and improve the growth and feed conversion efficiency of barramundi. The inclusion of SCP in the diet supports gut health and shows potential for sustainable aquaculture.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Fisheries
Stefanie M. Colombo, Koushik Roy, Jan Mraz, Alex H. L. Wan, Simon J. Davies, Sean M. Tibbetts, Margareth Overland, David S. Francis, Melissa M. Rocker, Laura Gasco, Emma Spencer, Marc Metian, Jesse T. Trushenski, Giovanni M. Turchini
Summary: This review describes the role and importance of 'blue-food production' in a circular bioeconomy, particularly in improving the sustainability and resilience of aquaculture. It also discusses emerging nutrient sources for fed-aquaculture species.
REVIEWS IN AQUACULTURE
(2023)
Review
Fisheries
Ha H. Truong, Barney M. Hines, Mauricio G. Emerenciano, David Blyth, Sarah Berry, Tansyn H. Noble, Nicholas A. Bourne, Nicholas Wade, Artur N. Rombenso, Cedric J. Simon
Summary: This review presents the current knowledge of mineral nutrition for penaeid shrimp, including the influence of the aquatic environment and shrimp lifecycle, methods of mineral supply, and requirements for individual minerals. With the intensification and diversification of shrimp aquaculture, mineral nutrition will become increasingly important.
REVIEWS IN AQUACULTURE
(2023)
Article
Agriculture, Dairy & Animal Science
T. H. Noble, F. Samsing, N. Wade, S. Osborne, R. Addepalli, J. W. Wynne
Summary: Immune stimulation through feed additives, such as the LPS component in NovacqTM, can effectively combat diseases in shrimp farming and reduce antibiotic usage. In this study, lipopolysaccharide-like molecules from NovacqTM were found to stimulate a rapid and significant induction of the phenoloxidase response in shrimp hemocytes. Transcriptome analysis revealed an up-regulation of immune-related genes and the activation of transcription factors in the hemocytes, indicating the strong immunostimulatory ability of NovacqTM.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Omar Mendoza-Porras, James A. Broadbent, David J. Beale, Sophia M. Escobar-Correas, Simone A. Osborne, Cedric J. Simon, Nicholas M. Wade
Summary: Black tiger shrimps respond differently to different diets in terms of nutrient assimilation and energy metabolism. Proteomics and metabolomics analyses showed that microbial biomass, krill meal, and fasting had distinct effects on the energy pathways and metabolic pathways of the shrimp. However, common energy strategies were observed during fasting or consumption of specific ingredients, with different diets influencing these pathways to varying extents.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2023)
Article
Marine & Freshwater Biology
Abdallah Ghonimy, Laura S. Lopez Greco, Jian Li, Nicholas M. Wade
Summary: This study explores the possibility of combining astaxanthin with specific fatty acids in crustaceans and the effects of L-carnitine on lipid metabolism. The results indicate that by adjusting the dietary ratios and including appropriate amounts of astaxanthin, L-carnitine, and specific fatty acids, it may be possible to further improve pigment utilization, lipid metabolism, health, and growth in crustaceans.
