Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis

Human Cerebrospinal Fluid Monoclonal LGI1 Autoantibodies Increase Neuronal Excitability

(2020) Hans‐Christian Kornau et al.   ANNALS OF NEUROLOGY

Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition

(2020) Sukhvir K. Wright et al.   Annals of Clinical and Translational Neurology

Epilepsy gene therapy using an engineered potassium channel

(2019) Albert Snowball et al.   JOURNAL OF NEUROSCIENCE

A mouse model of seizures in anti-N -methyl-d -aspartate receptor encephalitis

(2019) Olga Taraschenko et al.   EPILEPSIA

Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis

(2019) Marienke A.A.M. de Bruijn et al.   NEUROLOGY

Action of antiepileptic drugs on neurons

(2019) Katsuhiro Kobayashi et al.   BRAIN & DEVELOPMENT

Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors

(2019) Brian E. Jones et al.   Science Translational Medicine

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

(2019) Vincenzo Salpietro et al.   Nature Communications

Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus

(2019) Richard J Burman et al.   BRAIN

Changes in excitatory and inhibitory receptor expression and network activity during induction and establishment of epilepsy in the rat Reduced Intensity Status Epilepticus (RISE) model

(2019) Hope I. Needs et al.   NEUROPHARMACOLOGY

Ion channels in EEG: isolating channel dysfunction in NMDA receptor antibody encephalitis

(2018) Mkael Symmonds et al.   BRAIN

Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis

(2018) Natasha Warikoo et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent control of NMDA receptor subunit composition at hippocampal mossy fibre synapses

(2018) Mario Carta et al.   JOURNAL OF PHYSIOLOGY-LONDON

Phase-amplitude coupling and epileptogenesis in an animal model of mesial temporal lobe epilepsy

(2018) Soheila Samiee et al.   NEUROBIOLOGY OF DISEASE

Long-term neuropsychological outcome following pediatric anti-NMDAR encephalitis

(2018) Marienke A.A.M. de Bruijn et al.   NEUROLOGY

Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction

(2018) Holger Haselmann et al.   NEURON

NMDA-receptor antibodies alter cortical microcircuit dynamics

(2018) Richard E. Rosch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GRIN2A-related disorders: genotype and functional consequence predict phenotype

(2018) Vincent Strehlow et al.   BRAIN

From molecules to medicines: the dawn of targeted therapies for genetic epilepsies

(2018) Scott T. Demarest et al.   Nature Reviews Neurology

EEG analysis in anti-NMDA receptor encephalitis: Description of typical patterns

(2018) S. Jeannin-Mayer et al.   CLINICAL NEUROPHYSIOLOGY

Comparative Outcomes in Children and Adults With Anti-N-Methyl-D-Aspartate (anti-NMDA) Receptor Encephalitis

(2017) Eliza Gordon-Lipkin et al.   JOURNAL OF CHILD NEUROLOGY

All for One But Not One for All: Excitatory Synaptic Scaling and Intrinsic Excitability Are Coregulated by CaMKIV, Whereas Inhibitory Synaptic Scaling Is Under Independent Control

(2017) Annelise Joseph et al.   JOURNAL OF NEUROSCIENCE

Pregnenolone as an adjunct to risperidone for treatment of women with schizophrenia: A randomized double-blind placebo-controlled clinical trial

(2017) Ladan Kashani et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Time-dependent evolution of seizures in a model of mesial temporal lobe epilepsy

(2017) Charles Behr et al.   NEUROBIOLOGY OF DISEASE

Dynamic causal modelling of seizure activity in a rat model

(2017) Margarita Papadopoulou et al.   NEUROIMAGE

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody

(2017) Manish Malviya et al.   Annals of Clinical and Translational Neurology

Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity

(2016) Jesús Planagumà et al.   ANNALS OF NEUROLOGY

Human cerebrospinal fluid monoclonalN-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis

(2016) Jakob Kreye et al.   BRAIN

Stereotactic injection of cerebrospinal fluid from anti-NMDA receptor encephalitis into rat dentate gyrus impairs NMDA receptor function

(2016) Till Würdemann et al.   BRAIN RESEARCH

Human brain slices for epilepsy research: Pitfalls, solutions and future challenges

(2016) Roland S.G. Jones et al.   JOURNAL OF NEUROSCIENCE METHODS

A clinical approach to diagnosis of autoimmune encephalitis

(2016) Francesc Graus et al.   LANCET NEUROLOGY

Delineating the GRIN1 phenotypic spectrum

(2016) Johannes R. Lemke et al.   NEUROLOGY

A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat

(2016) Tamara Modebadze et al.   PLoS One

Cellular plasticity induced by anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis antibodies

(2015) Xiaoyu Peng et al.   ANNALS OF NEUROLOGY

N-methyl-D-aspartate receptor antibody-mediated neurological disease: results of a UK-based surveillance study in children

(2015) Sukhvir Wright et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Pyramidal Cell Selective Ablation of N-Methyl-D-Aspartate Receptor 1 Causes Increase in Cellular and Network Excitability

(2015) Valerie M. Tatard-Leitman et al.   BIOLOGICAL PSYCHIATRY

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

(2015) Sukhvir Wright et al.   BRAIN

Symptomatic treatment of children with anti-NMDAR encephalitis

(2015) Shekeeb S Mohammad et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients

(2015) R. Hoftberger et al.   NEUROLOGY

Atlas of the Postnatal Rat Brain in Stereotaxic Coordinates

(2015) Roustem Khazipov et al.   Frontiers in Neuroanatomy

Pediatric super-refractory status epilepticus treated with allopregnanolone

(2014) Eileen Broomall et al.   ANNALS OF NEUROLOGY

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease

(2014) R. C. Dale et al.   NEUROLOGY

Clinical specificities of adult male patients with NMDA receptor antibodies encephalitis

(2014) A. Viaccoz et al.   NEUROLOGY

Parvalbumin Cell Ablation of NMDA-R1 Causes Increased Resting Network Excitability with Associated Social and Self-Care Deficits

(2014) Eddie N Billingslea et al.   NEUROPSYCHOPHARMACOLOGY

Losing Control Under Ketamine: Suppressed Cortico-Hippocampal Drive Following Acute Ketamine in Rats

(2014) Rosalyn J Moran et al.   NEUROPSYCHOPHARMACOLOGY

Pregnenolone treatment reduces severity of negative symptoms in recent-onset schizophrenia: An 8-week, double-blind, randomized add-on two-center trial

(2014) Michael S. Ritsner et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia

(2014) Christine E. Marx et al.   PSYCHOPHARMACOLOGY

Pregnenolone sulfate as a modulator of synaptic plasticity

(2014) Conor C. Smith et al.   PSYCHOPHARMACOLOGY

Recurrent synapses and circuits in the CA3 region of the hippocampus: an associative network

(2014) Caroline Le Duigou et al.   Frontiers in Cellular Neuroscience

Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype

(2013) Sarosh R. Irani et al.   BRAIN

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

Pregnenolone Sulfate: From Steroid Metabolite to TRP Channel Ligand

(2013) Christian Harteneck   MOLECULES

Neural masses and fields in dynamic causal modeling

(2013) Rosalyn Moran et al.   Frontiers in Computational Neuroscience

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

(2012) Lenka Mikasova et al.   BRAIN

Canonical Microcircuits for Predictive Coding

(2012) Andre M. Bastos et al.   NEURON

Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice

(2012) Peiyan Wong et al.   PLoS One

Optogenetic and Potassium Channel Gene Therapy in a Rodent Model of Focal Neocortical Epilepsy

(2012) R. C. Wykes et al.   Science Translational Medicine

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients

(2011) Qing Zhang et al.   NEUROBIOLOGY OF DISEASE

Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission

(2010) Tatjana Lalic et al.   EPILEPSIA

Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies

(2010) Emilia H. Moscato et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Ablation of NMDA Receptors Enhances the Excitability of Hippocampal CA3 Neurons

(2009) Fumiaki Fukushima et al.   PLoS One

Neuroactive steroid regulation of neurotransmitter release in the CNS: Action, mechanism and possible significance

(2009) Ping Zheng   PROGRESS IN NEUROBIOLOGY

Dynamic causal modelling for EEG and MEG

(2008) Stefan J. Kiebel et al.   Cognitive Neurodynamics

Population dynamics: Variance and the sigmoid activation function

(2008) André C. Marreiros et al.   NEUROIMAGE

Dynamic causal models of steady-state responses

(2008) R.J. Moran et al.   NEUROIMAGE