Oxygen as a Master Regulator of Human Pluripotent Stem Cell Function and Metabolism
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Title
Oxygen as a Master Regulator of Human Pluripotent Stem Cell Function and Metabolism
Authors
Keywords
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Journal
Journal of Personalized Medicine
Volume 11, Issue 9, Pages 905
Publisher
MDPI AG
Online
2021-09-10
DOI
10.3390/jpm11090905
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Note: Only part of the references are listed.- HIF‐1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cells
- (2020) Peng Cui et al. FASEB JOURNAL
- Use of 3D Organoids as a Model to Study Idiopathic Form of Parkinson’s Disease
- (2020) Chlebanowska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modulation of oxygen tension, acidosis, and cell density is crucial for neural differentiation of human induced pluripotent stem cells
- (2020) Rina Okada et al. NEUROSCIENCE RESEARCH
- PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells
- (2020) Yanping Liu et al. Aging-US
- Hypoxia as a Driving Force of Pluripotent Stem Cell Reprogramming and Differentiation to Endothelial Cells
- (2020) Paulina Podkalicka et al. Biomolecules
- Induced pluripotent stem cells in disease modelling and drug discovery
- (2019) R. Grant Rowe et al. NATURE REVIEWS GENETICS
- Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux
- (2019) Jarmon G. Lees et al. Stem Cells International
- Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
- (2019) Daniela Cornacchia et al. Cell Stem Cell
- Current understanding and future perspectives of the roles of sirtuins in the reprogramming and differentiation of pluripotent stem cells
- (2018) Yi-Chao Hsu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Cancer stem cells and hypoxia-inducible factors (Review)
- (2018) Wei-Wei Tong et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Effects of hypoxia inducible factors on pluripotency in human iPS cells
- (2018) Kouji Sugimoto et al. MICROSCOPY RESEARCH AND TECHNIQUE
- Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid
- (2018) Xian-Yang Qin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
- (2018) Ronen Ben Jehuda et al. Stem Cell Reviews and Reports
- Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
- (2018) Ronen Ben Jehuda et al. Stem Cell Reviews and Reports
- Cancer stem cells-emanated therapy resistance: Implications for liposomal drug delivery systems
- (2018) Hassan Dianat-Moghadam et al. JOURNAL OF CONTROLLED RELEASE
- FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC
- (2018) Sisi Cao et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example
- (2018) Hana Golan et al. Stem Cell Reports
- Sphere-Formation Assay: Three-Dimensional in vitro Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells
- (2018) Hisham F. Bahmad et al. Frontiers in Oncology
- Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells
- (2018) Xiuying Zhong et al. Cell Metabolism
- A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome
- (2018) Ran Jing et al. Cell Reports
- MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming
- (2018) Javier Prieto et al. Stem Cell Reports
- The metabolic programming of stem cells
- (2017) Ng Shyh-Chang et al. GENES & DEVELOPMENT
- SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
- (2017) Chun-Ping Cui et al. GUT
- Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
- (2017) Miguel Crespo et al. NATURE MEDICINE
- Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
- (2017) Michiko Mandai et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia
- (2017) F Peng et al. ONCOGENE
- Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination
- (2017) Kalpana Mujoo et al. Stem Cell Reports
- A Role for KLF4 in Promoting the Metabolic Shift via TCL1 during Induced Pluripotent Stem Cell Generation
- (2017) Ken Nishimura et al. Stem Cell Reports
- Hallmarks of cancer stem cell metabolism
- (2016) Patricia Sancho et al. BRITISH JOURNAL OF CANCER
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells
- (2016) Shugo Tohyama et al. Cell Metabolism
- Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State
- (2016) Wen Gu et al. Cell Stem Cell
- Investigation of simvastatin-induced apoptosis and cell cycle arrest in cancer stem cells of MCF-7
- (2016) SeyedNasser Ostad et al. Journal of Cancer Research and Therapeutics
- Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
- (2016) Javier Prieto et al. Nature Communications
- Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1
- (2016) Yong-Joon Choi et al. Oncotarget
- NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming
- (2016) Kate E. Hawkins et al. Cell Reports
- MYC Is a Major Determinant of Mitotic Cell Fate
- (2015) Caroline Topham et al. CANCER CELL
- Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency
- (2015) Davide Cacchiarelli et al. CELL
- Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
- (2015) Arieh Moussaieff et al. Cell Metabolism
- ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency
- (2015) Yasuyuki S. Kida et al. Cell Stem Cell
- Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
- (2015) Lei Shi et al. CURRENT OPINION IN CELL BIOLOGY
- Emerging roles of hypoxia-inducible factors and reactive oxygen species in cancer and pluripotent stem cells
- (2015) Shigeo Saito et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency
- (2015) Hyunsoo Kim et al. STEM CELLS
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
- (2014) Yasuhiro Takashima et al. CELL
- Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
- (2014) Julie Mathieu et al. Cell Stem Cell
- High Oxygen Condition Facilitates the Differentiation of Mouse and Human Pluripotent Stem Cells into Pancreatic Progenitors and Insulin-producing Cells
- (2014) Farzana Hakim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
- (2014) Bryce W. Carey et al. NATURE
- SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress
- (2014) Xuan Ou et al. STEM CELLS
- The Differential Effects of 2% Oxygen Preconditioning on the Subsequent Differentiation of Mouse and Human Pluripotent Stem Cells
- (2014) Kate Fynes et al. STEM CELLS AND DEVELOPMENT
- Antioxidant Supplementation Reduces Genomic Aberrations in Human Induced Pluripotent Stem Cells
- (2014) Junfeng Ji et al. Stem Cell Reports
- Defining the Role of Oxygen Tension in Human Neural Progenitor Fate
- (2014) Yuan Xie et al. Stem Cell Reports
- Mitochondrial Regulation in Pluripotent Stem Cells
- (2013) Xiuling Xu et al. Cell Metabolism
- Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency
- (2013) Shuo Wang et al. Cell Stem Cell
- Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells
- (2013) Chao-Wan Guo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Hypoxia-enhanced Derivation of iPSCs from Human Dental Pulp Cells
- (2013) K. Iida et al. JOURNAL OF DENTAL RESEARCH
- Derivation of novel human ground state naive pluripotent stem cells
- (2013) Ohad Gafni et al. NATURE
- Continuous Hypoxic Culturing of Human Embryonic Stem Cells Enhances SSEA-3 and MYC Levels
- (2013) Elisa Närvä et al. PLoS One
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1-3 and PKM2
- (2013) Alessandro Prigione et al. STEM CELLS
- HIF1 is required for survival maintenance of chronic myeloid leukemia stem cells
- (2012) H. Zhang et al. BLOOD
- Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells
- (2012) Alejandro Vazquez-Martin et al. CELL CYCLE
- HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
- (2012) Wenyu Zhou et al. EMBO JOURNAL
- Introduction to Stem Cells and Regenerative Medicine
- (2012) George Kolios et al. RESPIRATION
- Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency
- (2012) Jenny Hansson et al. Cell Reports
- Control of the Embryonic Stem Cell State
- (2011) Richard A. Young CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Derivation of neural precursor cells from human ES cells at 3% O2 is efficient, enhances survival and presents no barrier to regional specification and functional differentiation
- (2011) S R L Stacpoole et al. CELL DEATH AND DIFFERENTIATION
- Anaerobicizing into Pluripotency
- (2011) Athanasia D. Panopoulos et al. Cell Metabolism
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- Biochemical and morphological effects of hypoxic environment on human embryonic stem cells in long-term culture and differentiating embryoid bodies
- (2011) Hee-Joung Lim et al. MOLECULES AND CELLS
- Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining
- (2011) Jinshui Fan et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Somatic coding mutations in human induced pluripotent stem cells
- (2011) Athurva Gore et al. NATURE
- An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
- (2011) Chad Tang et al. NATURE BIOTECHNOLOGY
- Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells
- (2011) Hua Fung et al. PLoS One
- A Universal System for Highly Efficient Cardiac Differentiation of Human Induced Pluripotent Stem Cells That Eliminates Interline Variability
- (2011) Paul W. Burridge et al. PLoS One
- Concise Review: Genomic Stability of Human Induced Pluripotent Stem Cells
- (2011) Kristen Martins-Taylor et al. STEM CELLS
- Hypoxia Enhances the Generation of Retinal Progenitor Cells from Human Induced Pluripotent and Embryonic Stem Cells
- (2011) Daekyeong Bae et al. STEM CELLS AND DEVELOPMENT
- Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
- (2010) Christopher J. Lengner et al. CELL
- Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds
- (2010) Saiyong Zhu et al. Cell Stem Cell
- Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
- (2010) Miguel Angel Esteban et al. Cell Stem Cell
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Targeting Hypoxic Cells through the DNA Damage Response
- (2010) M. Olcina et al. CLINICAL CANCER RESEARCH
- myc maintains embryonic stem cell pluripotency and self-renewal
- (2010) Natalia V. Varlakhanova et al. DIFFERENTIATION
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- Mild Hypoxia Enhances Proliferation and Multipotency of Human Neural Stem Cells
- (2010) Guido Santilli et al. PLoS One
- DNA Damage Responses in Human Induced Pluripotent Stem Cells and Embryonic Stem Cells
- (2010) Olga Momcilovic et al. PLoS One
- Hypoxia Promotes Efficient Differentiation of Human Embryonic Stem Cells to Functional Endothelium
- (2010) Sonia Prado-Lopez et al. STEM CELLS
- The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells
- (2010) Alessandro Prigione et al. STEM CELLS
- Intratumoral Hypoxic Gradient Drives Stem Cells Distribution and MGMT Expression in Glioblastoma
- (2010) Francesca Pistollato et al. STEM CELLS
- Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival
- (2010) J R Tejedo et al. Cell Death & Disease
- Role for Kruppel-Like Factor 4 in Determining the Outcome of p53 Response to DNA Damage
- (2009) Q. Zhou et al. CANCER RESEARCH
- Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells
- (2009) Yoshinori Yoshida et al. Cell Stem Cell
- The hematopoietic stem cell niche: Low in oxygen but a nice place to be
- (2009) Pernilla Eliasson et al. JOURNAL OF CELLULAR PHYSIOLOGY
- HIF2 inhibition promotes p53 pathway activity, tumor cell death, and radiation responses
- (2009) J. A. Bertout et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling early retinal development with human embryonic and induced pluripotent stem cells
- (2009) J. S. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions
- (2009) Catherine E Forristal et al. REPRODUCTION
- Regulation of gene expression by hypoxia
- (2008) Niall Steven Kenneth et al. BIOCHEMICAL JOURNAL
- Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor
- (2008) Sylvia Niebruegge et al. BIOTECHNOLOGY AND BIOENGINEERING
- Chronic Hypoxia Decreases Synthesis of Homologous Recombination Proteins to Offset Chemoresistance and Radioresistance
- (2008) N. Chan et al. CANCER RESEARCH
- A reduced oxygen tension (5%) is not beneficial for maintaining human embryonic stem cells in the undifferentiated state with short splitting intervals
- (2008) H.-F. Chen et al. HUMAN REPRODUCTION
- Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality
- (2008) E.J. Koay et al. OSTEOARTHRITIS AND CARTILAGE
- Transcriptome alterations due to physiological normoxic (2% O2) culture of human embryonic stem cells
- (2008) Nicholas R Forsyth et al. Regenerative Medicine
- Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells
- (2008) Ivana Rosová et al. STEM CELLS
- Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells
- (2008) Suzanne D. Westfall et al. STEM CELLS AND DEVELOPMENT
- Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche
- (2007) Yoshiaki Kubota et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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