The Potential Protective Effect of Mesencephalic Astrocyte-Derived Neurotrophic Factor on Post-Operative Delirium via Inhibiting Inflammation and Microglia Activation

The pharmacotherapeutic management of postoperative delirium: an expert update

(2020) Angela Scicutella   EXPERT OPINION ON PHARMACOTHERAPY

Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients

(2020) Yi Yuan et al.   Frontiers in Aging Neuroscience

Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation

(2020) Wenchao Zhang et al.   Frontiers in Pharmacology

The relationship between DNA methylation in neurotrophic genes and age as evidenced from three independent cohorts: differences by delirium status

(2020) Taku Saito et al.   NEUROBIOLOGY OF AGING

Antipsychotic Drugs in Prevention of Postoperative Delirium—What Is Known in 2020?

(2020) Michał P. Pluta et al.   International Journal of Environmental Research and Public Health

Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

(2019) Shengchun Xu et al.   Journal of Neuroinflammation

Acute postoperative pain exacerbates neuroinflammation and related delirium-like cognitive dysfunction in rats

(2019) Tsuyoshi Koyama et al.   Journal of Anesthesia

Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats

(2019) Atsushi Nishigaki et al.   Journal of Anesthesia

MANF inhibits liver cancer via SUMO ylation‐related suppression of NF ‐κB/Snail signaling pathway and epithelial‐mesenchymal transition

(2019) Jun Liu et al.   HEPATOLOGY

Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit

(2019) Kazuhito Mietani et al.   PLoS One

Circulating Mesencephalic Astrocyte-derived Neurotrophic Factor Negatively Correlates with Atrial Apoptosis in Human Chronic Atrial Fibrillation

(2019) Changhui Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Postoperative delirium is associated with increased plasma neurofilament light

(2019) Cameron P Casey et al.   BRAIN

Clinical predictors of postoperative delirium, functional status, and mortality in geriatric patients undergoing non-elective surgery for hip fracture

(2019) Mark J. Harris et al.   JOURNAL OF CLINICAL ANESTHESIA

Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies

(2018) Xuling Liu et al.   PLoS One

The physiology of endocrine systems with ageing

(2018) Annewieke W van den Beld et al.   Lancet Diabetes & Endocrinology

Poststroke delivery of MANF promotes functional recovery in rats

(2018) Kert Mätlik et al.   Science Advances

In-depth characterization of the neuroinflammatory reaction induced by peripheral surgery in an animal model

(2018) Konstanze Plaschke et al.   JOURNAL OF NEURAL TRANSMISSION

Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults

(2018) Gene L. Bowman et al.   Alzheimers & Dementia

MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic β-Cell Mass in Mice

(2018) Tatiana Danilova et al.   DIABETES

From Systemic Inflammation to Neuroinflammation: The Case of Neurolupus

(2018) Mykolas Bendorius et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Postoperative cognitive dysfunction – current preventive strategies

(2018) Nalini Kotekar et al.   Clinical Interventions in Aging

Long-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats

(2017) Fei Hao et al.   EXPERIMENTAL NEUROLOGY

Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery

(2017) Xi Xin et al.   Journal of Neuroinflammation

Delirium

(2017) Belinda Setters et al.   PRIMARY CARE

Immune modulation by MANF promotes tissue repair and regenerative success in the retina

(2016) J. Neves et al.   SCIENCE

Battery of behavioral tests in mice to study postoperative delirium

(2016) Mian Peng et al.   Scientific Reports

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

(2016) Emilia Galli et al.   Scientific Reports

ER stress-inducible protein MANF selectively expresses in human spleen

(2015) Jun Liu et al.   HUMAN IMMUNOLOGY

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Involved in Inflammation by Negatively Regulating the NF-κB Pathway

(2015) Lijian Chen et al.   Scientific Reports

Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis

(2014) Wen Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Role of CRP, TNF-a, and IGF-1 in Delirium Pathophysiology

(2014) Mehmet Alper Cinar et al.   Noropsikiyatri Arsivi-Archives of Neuropsychiatry

Systemic infection and delirium: when cytokines and acetylcholine collide

(2010) Willem A van Gool et al.   LANCET