In vivo Pharmacokinetic and Anticancer Studies of HH-N25, a Selective Inhibitor of Topoisomerase I, and Hormonal Signaling for Treating Breast Cancer

Pharmacoinformatics and Preclinical Studies of NSC765690 and NSC765599, Potential STAT3/CDK2/4/6 Inhibitors with Antitumor Activities against NCI60 Human Tumor Cell Lines

(2021) Bashir Lawal et al.   Biomedicines

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020

(2021) Wei Cao et al.   CHINESE MEDICAL JOURNAL

Cancer statistics for the year 2020: An overview

(2021) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

(2021) Nicole A. Traphagen et al.   ONCOGENE

mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

(2021) Bashir Lawal et al.   Frontiers in Oncology

Pro-Oncogenic c-Met/EGFR, Biomarker Signatures of the Tumor Microenvironment are Clinical and Therapy Response Prognosticators in Colorectal Cancer, and Therapeutic Targets of 3-Phenyl-2H-benzo[e][1,3]-Oxazine-2,4(3H)-Dione Derivatives

(2021) Bashir Lawal et al.   Frontiers in Pharmacology

Identification of Cancer Hub Gene Signatures Associated with Immune-Suppressive Tumor Microenvironment and Ovatodiolide as a Potential Cancer Immunotherapeutic Agent

(2021) Jia-Hong Chen et al.   Cancers

Development and Validation of a Simple and Rapid Ultrahigh-Performance Liquid Chromatography Tandem Spectrometry Method for the Quantification of Hydroxychloroquine in Plasma and Blood Samples in the Emergency Context of SARS-CoV-2 Pandemic

(2020) Natalia Doudka et al.   THERAPEUTIC DRUG MONITORING

Breast Cancer Treatment

(2019) Adrienne G. Waks et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Topoisomerase Inhibitors and Targeted Delivery in Cancer Therapy

(2019) Fei You et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents

(2016) Tsung-Chih Chen et al.   Arabian Journal of Chemistry

Design, Synthesis andin vitroAnticancer Activity of a Cu(II) Complex of Carminic Acid: A Novel Small Molecule Inhibitor of Human DNA Topoisomerase I and Topoisomerase II

(2016) Piyal Das et al.   ChemistrySelect

Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents

(2015) Tsung-Chih Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In Vitro and In Vivo Anticancer Activity of Root Extracts ofSansevieria libericaGerome and Labroy (Agavaceae)

(2015) Abidemi J. Akindele et al.   Evidence-based Complementary and Alternative Medicine

Discovery of Novel Multiacting Topoisomerase I/II and Histone Deacetylase Inhibitors

(2015) Shipeng He et al.   ACS Medicinal Chemistry Letters

Advances in P-glycoprotein-based approaches for delivering anticancer drugs: pharmacokinetic perspective and clinical relevance

(2013) Ankit Saneja et al.   Expert Opinion on Drug Delivery

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

(2011) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to chemotherapy in breast tumor cells

(2010) Xu Di et al.   BREAST CANCER RESEARCH AND TREATMENT

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Ron J. Keizer et al.   CLINICAL PHARMACOKINETICS

In Vitro Cytotoxicity and In Vivo Efficacy, Pharmacokinetics, and Metabolism of 10074-G5, a Novel Small-Molecule Inhibitor of c-Myc/Max Dimerization

(2010) D. M. Clausen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,11-dione homologues

(2009) Hsu-Shan Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Breast Cancer in Young Women: Poor Survival Despite Intensive Treatment

(2009) Hanna Fredholm et al.   PLoS One

Some benzoxazoles and benzimidazoles as DNA topoisomerase I and II inhibitors

(2008) Emine Oksuzoglu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY