Propofol Ameliorates Exaggerated Human Neutrophil Activation in a LPS Sepsis Model

Illuminating the immunopathology of SARS‐CoV ‐2

(2021) Suraj Saksena et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Potential Impact of Local Anesthetics Inducing Granulocyte Arrest and Altering Immune Functions on Perioperative Outcome

(2021) Gesche Kolle et al.   Journal of Inflammation Research

The influence of extracellular tissue on neutrophil function and its possible linkage to inflammatory diseases

(2021) Richard F. Kraus et al.   Immunity Inflammation and Disease

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Neutrophils as emerging therapeutic targets

(2020) Tamás Németh et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic Anticoagulation with Argatroban and Heparins Reduces Granulocyte Migration: Possible Impact on ECLS-Therapy?

(2020) Andre Bredthauer et al.   Cardiovascular Therapeutics

Sedation for critically ill patients with COVID-19: Which specificities? One size does not fit all

(2020) Jean-François Payen et al.   Anaesthesia Critical Care & Pain Medicine

Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19

(2020) Bhawna Tomar et al.   Cells

Polymorphonuclear Cell Chemotaxis and Suicidal NETosis: Simultaneous Observation Using fMLP, PMA, H7, and Live Cell Imaging

(2020) Delou Pai et al.   Journal of Immunology Research

COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps

(2020) Leandro Borges et al.   MEDIATORS OF INFLAMMATION

Clinical characteristics and outcomes of critically ill patients with COVID-19 admitted to an intensive care unit in London: A prospective observational cohort study

(2020) Ross J. Thomson et al.   PLoS One

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Propofol specifically reduces PMA-induced neutrophil extracellular trap formation through inhibition of p-ERK and HOCl

(2019) Ming-Shan Chen et al.   LIFE SCIENCES

Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion

(2019) Angela Meier et al.   Frontiers in Pharmacology

Sodium Channel Nav1.3 Is Expressed by Polymorphonuclear Neutrophils during Mouse Heart and Kidney Ischemia In Vivo and Regulates Adhesion, Transmigration, and Chemotaxis of Human and Mouse Neutrophils In Vitro

(2018) Marit Poffers et al.   ANESTHESIOLOGY

Clinical Pharmacokinetics and Pharmacodynamics of Propofol

(2018) Marko M. Sahinovic et al.   CLINICAL PHARMACOKINETICS

High Level of Neutrophil Extracellular Traps Correlates With Poor Prognosis of Severe Influenza A Infection

(2018) Liuluan Zhu et al.   JOURNAL OF INFECTIOUS DISEASES

Propofol inhibits endogenous formyl peptide-induced neutrophil activation and alleviates lung injury

(2018) Chun-Yu Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endotoxin-induced autocrine ATP signaling inhibits neutrophil chemotaxis through enhancing myosin light chain phosphorylation

(2017) Xu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

(2016) Carolin Fleischmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway

(2016) Xu Wang et al.   Oncotarget

Propofol as a transformative drug in anesthesia: insights from key early investigators

(2015) Brian T. Bateman et al.   DRUG DISCOVERY TODAY

The mesenterially perfused rat small intestine: A versatile approach for pharmacological testings

(2014) Dominik Schreiber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Pharmacogenetics, Plasma Concentrations, Clinical Signs and EEG During Propofol Treatment

(2014) Muhammad Suleman Khan et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit

(2014) Jean-Louis Vincent et al.   Lancet Respiratory Medicine

Benzodiazepine Augmented γ-Amino-Butyric Acid Signaling Increases Mortality From Pneumonia in Mice*

(2013) Robert D. Sanders et al.   CRITICAL CARE MEDICINE

Propofol Inhibits Superoxide Production, Elastase Release, and Chemotaxis in Formyl Peptide-Activated Human Neutrophils by Blocking Formyl Peptide Receptor 1

(2013) S.-C. Yang et al.   JOURNAL OF IMMUNOLOGY

Current Epidemiology and Growing Resistance of Gram-Negative Pathogens

(2012) David M. Livermore   KOREAN JOURNAL OF INTERNAL MEDICINE

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

(2010) Theodore J. Iwashyna et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Propofol: A review of its non-anaesthetic effects

(2009) Ioanna Vasileiou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Flow-cytometric measurement of respiratory burst in rat polymorphonuclear granulocytes: Comparison of four cell preparation procedures, and concentration–response evaluation of soluble stimulants

(2008) Diane I. Bitzinger et al.   CYTOMETRY PART A