RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients

RGTA ® -based matrix therapy – A new branch of regenerative medicine in locomotion

(2017) Denis Barritault et al.   JOINT BONE SPINE

Efficacy of a New Heparan Sulfate Mimetic Dressing in the Healing of Foot and Lower Extremity Ulcerations in Type 2 Diabetes

(2016) Nikolaos Papanas et al.   International Journal of Lower Extremity Wounds

Effect of the Regenerative Agent Poly(Carboxymethylglucose Sulfate) on Corneal Wound Healing After Corneal Cross-Linking for Keratoconus

(2015) George D. Kymionis et al.   CORNEA

Combined Topical Application of a Regenerative Agent With a Bandage Contact Lens for the Treatment of Persistent Epithelial Defects

(2014) George D. Kymionis et al.   CORNEA

Cicatrisation d’un ulcère de cornée neurotrophique résistant par thérapie matricielle

(2014) A. Pison et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Long-Term Follow-up of Superficial Digital Flexor Tendonitis Treated by a Single Intralesional Injection of a ReGeneraTing Agent in 51 Horses

(2014) Virginie Coudry et al.   JOURNAL OF EQUINE VETERINARY SCIENCE

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Refractory sickle cell leg ulcer: is heparan sulphate a new hope?

(2014) Shady Hayek et al.   International Wound Journal

Topical treatment with a new matrix therapy agent (RGTA) in combination with limbal allograft in ocular surface desease and corneal anesthesia

(2013) E MARINGE et al.   ACTA OPHTHALMOLOGICA

RGTA-based matrix therapy in severe experimental corneal lesions: Safety and efficacy studies

(2013) F. Brignole-Baudouin et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

(2013) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stewart-Bluefarb syndrome: review of the literature and case report of chronic ulcer treatment with heparan sulphate (Cacipliq20®)

(2013) Shady Hayek et al.   International Wound Journal

Diabetes-Impaired Wound Healing Is Improved by Matrix Therapy With Heparan Sulfate Glycosaminoglycan Mimetic OTR4120 in Rats

(2012) M. Tong et al.   DIABETES

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Utilisation d’un agent biodégradable de la régénération tissulaire (RGTA) dans le traitement d’un ulcère trophique résistant d’origine zostérienne : à propos d’un cas

(2011) I. De Monchy et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Matrix Therapy with RGTA OTR4120 Improves Healing Time and Quality in Hairless Rats with Deep Second-Degree Burns

(2011) Gilbert Zakine et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells

(2011) Guilhem Frescaline et al.   Stem Cell Research

ReGeneraTing Agents Matrix Therapy Regenerates a Functional Root Attachment in Hamsters with Periodontitis

(2011) Corinne Lallam-Laroye et al.   TISSUE ENGINEERING PART A

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

(2011) R. O. Hynes et al.   Cold Spring Harbor Perspectives in Biology

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Premières applications de la thérapie matricielle en chirurgie plastique et esthétique

(2010) G. Zakine et al.   Annales de Chirurgie Plastique Esthetique

Synthesis and biological activities of a library of glycosaminoglycans mimetic oligosaccharides

(2010) Yasunori Ikeda et al.   BIOMATERIALS

Toxicological evaluation of RGTA OTR4120, a heparan sulfate mimetic

(2010) Said Charef et al.   FOOD AND CHEMICAL TOXICOLOGY

Regenerating matrix-based therapy for chronic wound healing: a prospective within-subject pilot study

(2010) Suzanne L Groah et al.   International Wound Journal

Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic

(2009) X-L Yue et al.   CELL DEATH AND DIFFERENTIATION

Glycosaminoglycan mimetics–induced mobilization of hematopoietic progenitors and stem cells into mouse peripheral blood: Structure/function insights∗

(2009) Patricia Albanese et al.   EXPERIMENTAL HEMATOLOGY

Differential Effect Triggered by a Heparan Mimetic of the RGTA Family Preventing Oral Mucositis Without Tumor Protection

(2009) Monica Mangoni et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Étude pilote d’un nouvel agent de thérapie matricielle (RGTA OTR4120®) dans les ulcères de cornée et les dystrophies cornéennes rebelles

(2008) C. Khammari Chebbi et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Matrix therapy in regenerative medicine, a new approach to chronic wound healing

(2008) V. Barbier-Chassefière et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Significant reduction in neural adhesions after administration of the regenerating agent OTR4120, a synthetic glycosaminoglycan mimetic, after peripheral nerve injury in rats

(2008) H. Mischa Zuijdendorp et al.   JOURNAL OF NEUROSURGERY