Regression Modeling of the Antioxidant-to-Nephroprotective Relation Shows the Pivotal Role of Oxidative Stress in Cisplatin Nephrotoxicity

Mitochondrial Electron Transport: Oxidative Phosphorylation, Mitochondrial Oxidant Production, and Methods of Measurement

(2020) Deirdre Nolfi-Donegan et al.   Redox Biology

The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats

(2020) Alfredo G. Casanova et al.   Translational Research

Differential effect of NDGA on cisplatin-induced nephrotoxicity in Spargue-Dawley rats

(2019) Nitin Mundhe et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Disulfiram and Its Copper Chelate Attenuate Cisplatin-Induced Acute Nephrotoxicity in Rats Via Reduction of Oxidative Stress and Inflammation

(2019) Shraddha I. Khairnar et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Arginyl-fructosyl-glucose, a Major Maillard Reaction Product of Red Ginseng, Attenuates Cisplatin-Induced Acute Kidney Injury by Regulating Nuclear Factor κB and Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathways

(2019) Rong-yan Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease

(2019) Sarah I. Landau et al.   KIDNEY INTERNATIONAL

The Mitochondrial Permeability Transition in Mitochondrial Disorders

(2019) Justina Šileikytė et al.   Oxidative Medicine and Cellular Longevity

How do Kidneys Adapt to a Deficit or Loss in Nephron Number?

(2019) Hadi Fattah et al.   PHYSIOLOGY

N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor

(2019) Shuai Huang et al.   Biomed Research International

Can acetylcysteine ameliorate cisplatin‐induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double‐blind, placebo‐controlled trial involving patients with head and neck cancer

(2019) Marília B. Visacri et al.   Cancer Medicine

Protective effects of zingerone on cisplatin-induced nephrotoxicity in female rats

(2019) Fatih Mehmet Kandemir et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity in rats: Impact on PPAR-γ, inflammation, apoptosis and Wnt/β-catenin pathway

(2019) Alaa M. Badawy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis

(2019) Xinliang Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Systematic review and meta-analysis of the efficacy of clinically tested protectants of cisplatin nephrotoxicity

(2019) Alfredo G. Casanova et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Treatment with troxerutin protects against cisplatin-induced kidney injury in mice

(2018) Fereshteh Dehnamaki et al.   ACTA CHIRURGICA BELGICA

Protective effects of zingerone on oxidative stress and inflammation in cisplatin-induced rat nephrotoxicity

(2018) Tuba Alibakhshi et al.   BIOMEDICINE & PHARMACOTHERAPY

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

Dunnione protects against experimental cisplatin-induced nephrotoxicity by modulating NQO1 and NAD+ levels

(2018) Saeed Nazari Soltan Ahmad et al.   FREE RADICAL RESEARCH

Xanthohumol attenuates cisplatin-induced nephrotoxicity through inhibiting NF-κB and activating Nrf2 signaling pathways

(2018) Fan Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prophylactic Effect of Diacerein against Cisplatin-Induced Nephrotoxicity in Rats

(2018) Ayman Geddawy et al.   International Journal of Pharmacology

Improvement of Cisplatin-induced renal dysfunction by Schisandra chinensis stems via anti-inflammation and anti-apoptosis effects

(2018) Yan-Zi Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

N -acetylcysteine transforms necrosis into apoptosis and affords tailored protection from cisplatin cytotoxicity

(2018) Sandra M. Sancho-Martínez et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells

(2018) Min Jung Kong et al.   Cell Death & Disease

Honey protects against cisplatin-induced hepatic and renal toxicity through inhibition of NF-κB-mediated COX-2 expression and the oxidative stress dependent BAX/Bcl-2/caspase-3 apoptotic pathway

(2018) Thikryat Neamatallah et al.   Food & Function

Protective Effect of Nanoceria on Cisplatin-Induced Nephrotoxicity by Amelioration of Oxidative Stress and Pro-inflammatory Mechanisms

(2018) Mohd Aslam Saifi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Insights into the respiratory chain and oxidative stress

(2018) V. Larosa et al.   BIOSCIENCE REPORTS

Kidney Protection Effect of Ginsenoside Re and Its Underlying Mechanisms on Cisplatin-Induced Kidney Injury

(2018) Zi Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes

(2018) Jay C. Jha et al.   CLINICAL SCIENCE

The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

(2018) Xiao-jie Mi et al.   Scientific Reports

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

(2018) Xiaowen Yu et al.   EBioMedicine

Daphnetin protects against cisplatin-induced nephrotoxicity by inhibiting inflammatory and oxidative response

(2018) Lina Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice

(2018) Jung-Yeon Kim et al.   MEDIATORS OF INFLAMMATION

Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice

(2018) Zeng Qi et al.   MOLECULES

Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats

(2017) Erliasa Bami et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues

(2017) Penélope D. Sánchez-González et al.   FOOD AND CHEMICAL TOXICOLOGY

Cisplatin nephrotoxicity: a review of the literature

(2017) Sandhya Manohar et al.   JOURNAL OF NEPHROLOGY

Mechanisms involved in the possible nephroprotective effect of rutin and low dose γ irradiation against cisplatin-induced nephropathy in rats

(2017) Rasha R. Radwan et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Puerarin attenuates cisplatin-induced rat nephrotoxicity: The involvement of TLR4/NF-κB signaling pathway

(2017) Xu Ma et al.   PLoS One

Key role of oxidative stress in animal models of aminoglycoside nephrotoxicity revealed by a systematic analysis of the antioxidant-to-nephroprotective correlation

(2017) Alfredo G. Casanova et al.   TOXICOLOGY

Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

(2017) Yu-Ching Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synergistic protective effect of N-acetylcysteine and taurine against cisplatin-induced nephrotoxicity in rats

(2017) Wessam Abdel-Wahab et al.   Drug Design Development and Therapy

Nebivolol Ameliorates Cisplatin-Induced Nephrotoxicity in Rats

(2016) Mohamed A. Morsy et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Nephrotoxicity of cisplatin combination chemotherapy in thoracic malignancy patients with CKD risk factors

(2016) Ko Sato et al.   BMC CANCER

Renal protective effects of arjunolic acid in a cisplatin-induced nephrotoxicity model

(2016) Nehal M. Elsherbiny et al.   CYTOKINE

Combined treatment of epigallocatechin gallate and Coenzyme Q10 attenuates cisplatin-induced nephrotoxicity via suppression of oxidative/nitrosative stress, inflammation and cellular damage

(2016) Sabiha Fatima et al.   FOOD AND CHEMICAL TOXICOLOGY

Nanoceria restrains PM2.5-induced metabolic disorder and hypothalamus inflammation by inhibition of astrocytes activation related NF-κB pathway in Nrf2 deficient mice

(2016) Min-Xuan Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sappanone A protects mice against cisplatin-induced kidney injury

(2016) Lin Kang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Vitamin E mitigates cisplatin-induced nephrotoxicity due to reversal of oxidative/nitrosative stress, suppression of inflammation and reduction of total renal platinum accumulation

(2016) Mostafa A. Darwish et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

(2016) Tarique Hussain et al.   Oxidative Medicine and Cellular Longevity

Ameliorative effect ofApodytes dimidiataon cisplatin-induced nephrotoxicity in Wistar rats

(2016) Menon Kunnathully Divya et al.   PHARMACEUTICAL BIOLOGY

Curcumin counteracts cisplatin-induced nephrotoxicity by preventing renal tubular cell apoptosis

(2016) Yeter Topcu-Tarladacalisir et al.   RENAL FAILURE

Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1

(2016) Reem N. El-Naga et al.   Scientific Reports

Nephrotoxicity as a Dose-Limiting Factor in a High-Dose Cisplatin-Based Chemoradiotherapy Regimen for Head and Neck Carcinomas

(2016) Jantien Hoek et al.   Cancers

Amniotic Fluid-Derived Mesenchymal Stem Cells Cut Short the Acuteness of Cisplatin-Induced Nephrotoxicity in Sprague-Dawley Rats

(2016) Fatma Al-Husseiny et al.   International Journal of Stem Cells

P53 Contributes to Cisplatin Induced Renal Oxidative Damage via Regulating P66shc and MnSOD

(2015) Yanggang Yuan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nobiletin ameliorates cisplatin-induced acute kidney injury due to its anti-oxidant, anti-inflammatory and anti-apoptotic effects

(2015) Salma Malik et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Nordihydroguaiaretic acid ameliorates cisplatin induced nephrotoxicity and potentiates its anti-tumor activity in DMBA induced breast cancer in female Sprague–Dawley rats

(2015) Nitin Arunrao Mundhe et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chronic Kidney Disease Influences Multiple Systems: Describing the Relationship between Oxidative Stress, Inflammation, Kidney Damage, and Concomitant Disease

(2015) Patrick S. Tucker et al.   Oxidative Medicine and Cellular Longevity

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

An integrated view of cisplatin-induced nephrotoxicity and ototoxicity

(2015) Takatoshi Karasawa et al.   TOXICOLOGY LETTERS

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Evidence of oxidative stress and mitochondrial respiratory chain dysfunction in an in vitro model of sepsis-induced kidney injury

(2014) C. Quoilin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Comparative In Vivo Evaluations of Curcumin and Its Analog Difluorinated Curcumin Against Cisplatin-Induced Nephrotoxicity

(2014) Kazim Sahin et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Amelioration of cisplatin-induced nephrotoxicity in rats by triterpenoid saponin of Terminalia arjuna

(2014) Iman O. Sherif   Clinical and Experimental Nephrology

Selective ETA receptor blockade protects against cisplatin-induced acute renal failure in male rats

(2014) Mai M. Helmy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Thalidomide Ameliorates Cisplatin-Induced Nephrotoxicity by Inhibiting Renal Inflammation in an Experimental Model

(2014) Keyvan Amirshahrokhi et al.   INFLAMMATION

N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models

(2014) Leslie L. Muldoon et al.   JOURNAL OF NEURO-ONCOLOGY

Cisplatinum nephrotoxicity in oncology therapeutics: retrospective review of patients treated between 2005 and 2012

(2014) Morgan Finkel et al.   PEDIATRIC NEPHROLOGY

Biochemical and histologic study of lethal cisplatin nephrotoxicity prevention by mirtazapine

(2014) Mustafa Talip Sener et al.   Pharmacological Reports

C-Phycocyanin prevents cisplatin-induced nephrotoxicity through inhibition of oxidative stress

(2014) Berenice Fernández-Rojas et al.   Food & Function

Azadirachta indicaAttenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

(2014) Ahmed E. Abdel Moneim et al.   Biomed Research International

Oxidative Stress in Hypertension: Role of the Kidney

(2013) Magali Araujo et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of oxidative stress during inflammatory processes

(2013) Jérôme Lugrin et al.   BIOLOGICAL CHEMISTRY

Amelioration of cisplatin-induced nephrotoxicity by grape seed extract and fish oil is mediated by lowering oxidative stress and DNA damage

(2013) Hanaa A. Hassan et al.   CYTOTECHNOLOGY

Cisplatin: an old drug with a newfound efficacy – from mechanisms of action to cytotoxicity

(2013) Antonio Macciò et al.   EXPERT OPINION ON PHARMACOTHERAPY

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference

(2013) Patrick T. Murray et al.   KIDNEY INTERNATIONAL

Pre-treatment with cardamonin protects against cisplatin-induced nephrotoxicity in rats: Impact on NOX-1, inflammation and apoptosis

(2013) Reem N. El-Naga   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Nephroprotective Properties of Recombinant Human Erythropoietin in Kidney Transplantation: Experimental Facts and Clinical Proofs

(2012) N. Pallet et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Carbamylated Erythropoietin Ameliorates Cyclosporine Nephropathy without Stimulating Erythropoiesis

(2012) Toyofumi Abe et al.   CELL TRANSPLANTATION

Mitochondrial Control of Cellular Life, Stress, and Death

(2012) Lorenzo Galluzzi et al.   CIRCULATION RESEARCH

Subcellular targets of cisplatin cytotoxicity: An integrated view

(2012) Sandra M. Sancho-Martínez et al.   PHARMACOLOGY & THERAPEUTICS

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

(2011) Penélope D. Sánchez-González et al.   CRITICAL REVIEWS IN TOXICOLOGY

Effect of erythropoietin therapy on the progression of cisplatin induced renal injury in rats

(2011) Hoda E. Mohamed et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity

(2011) P. D. Sanchez-Gonzalez et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Necrotic Concentrations of Cisplatin Activate the Apoptotic Machinery but Inhibit Effector Caspases and Interfere with the Execution of Apoptosis

(2011) Sandra M. Sancho-Martínez et al.   TOXICOLOGICAL SCIENCES

Erythropoietin (EPO) in acute kidney injury

(2011) Elizabeth Moore et al.   Annals of Intensive Care

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Amelioration of cisplatin-induced nephrotoxicity by pravastatin in mice

(2010) Yi An et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Uncoupling protein-2 knockdown mediates the cytotoxic effects of cisplatin

(2010) Francisca M. Santandreu et al.   FREE RADICAL BIOLOGY AND MEDICINE

New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view

(2010) Jose M. Lopez-Novoa et al.   KIDNEY INTERNATIONAL

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In vivo anti-inflammatory and wound healing activities of Centaurea iberica Trev. ex Spreng

(2009) Ufuk Koca et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-inflammatory Properties of Cerium Oxide Nanoparticles

(2009) Suzanne M. Hirst et al.   Small

Cisplatin impairs rat liver mitochondrial functions by inducing changes on membrane ion permeability: Prevention by thiol group protecting agents

(2009) José B.A. Custódio et al.   TOXICOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity

(2008) Yolanda I. Chirino et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells

(2007) Alexander Vogetseder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protective effects of apocynin against cisplatin-induced oxidative stress and nephrotoxicity

(2007) Yolanda I. Chirino et al.   TOXICOLOGY