MEK1/2-ERK Pathway Alterations as a Therapeutic Target in Sporadic Alzheimer’s Disease: A Study in Senescence-Accelerated OXYS Rats

“Amyloid‐beta accumulation cycle” as a prevention and/or therapy target for Alzheimer's disease

(2020) Chinthalapally V. Rao et al.   AGING CELL

Single-Nucleotide Polymorphisms Associated with the Senescence-Accelerated Phenotype of OXYS Rats: A Focus on Alzheimer’s Disease-Like and Age-Related-Macular-Degeneration-Like Pathologies

(2020) Vasiliy A. Devyatkin et al.   JOURNAL OF ALZHEIMERS DISEASE

MAP/ERK Signaling in Developing Cognitive and Emotional Function and Its Effect on Pathological and Neurodegenerative Processes

(2020) Héctor Albert-Gascó et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats

(2020) Natalia A. Muraleva et al.   Antioxidants

Map kinase signaling as therapeutic target for neurodegeneration

(2020) Touqeer Ahmed et al.   PHARMACOLOGICAL RESEARCH

p38 MAPK–dependent alphaB-crystallin phosphorylation in Alzheimer's disease–like pathology in OXYS rats

(2019) N.A. Muraleva et al.   EXPERIMENTAL GERONTOLOGY

Suppression of Alzheimer’s Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study

(2019) Natalia A. Stefanova et al.   Oxidative Medicine and Cellular Longevity

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer’s models

(2018) Altan Rentsendorj et al.   BRAIN BEHAVIOR AND IMMUNITY

Alzheimer's Disease-Like Pathology in Senescence-Accelerated OXYS Rats can be Partially Retarded with Mitochondria-Targeted Antioxidant SkQ1

(2018) Natalia A. Stefanova et al.   JOURNAL OF ALZHEIMERS DISEASE

Decrease of ERK/MAPK Overactivation in Prefrontal Cortex Reverses Early Memory Deficit in a Mouse Model of Alzheimer's Disease

(2018) Mariana Feld et al.   JOURNAL OF ALZHEIMERS DISEASE

Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice

(2018) Charles E. Evans et al.   NEUROBIOLOGY OF AGING

The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review)

(2017) Jing Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation

(2017) J Xu et al.   Oncogenesis

Behavioral Effects Induced by Mitochondria-Targeted Antioxidant SkQ1 in Wistar and Senescence-Accelerated OXYS Rats

(2017) Natalia A. Stefanova et al.   JOURNAL OF ALZHEIMERS DISEASE

An antioxidant specifically targeting mitochondria delays progression of Alzheimer’s disease-like pathology

(2016) Natalia Stefanova et al.   Aging-US

Neurotransmitter release: vacuolar ATPase V0 sector c-subunits in possible gene or cell therapies for Parkinson’s, Alzheimer’s, and psychiatric diseases

(2016) Haruhiro Higashida et al.   Journal of Physiological Sciences

Hippocampal Injections of Oligomeric Amyloid β-peptide (1–42) Induce Selective Working Memory Deficits and Long-lasting Alterations of ERK Signaling Pathway

(2016) Pierre Faucher et al.   Frontiers in Aging Neuroscience

Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling

(2016) Ya Wen et al.   PLoS One

Senescence-accelerated OXYS rats: A model of age-related cognitive decline with relevance to abnormalities in Alzheimer disease

(2014) Natalia Stefanova et al.   CELL CYCLE

ATP6V0C Knockdown in Neuroblastoma Cells Alters Autophagy-Lysosome Pathway Function and Metabolism of Proteins that Accumulate in Neurodegenerative Disease

(2014) Leandra R. Mangieri et al.   PLoS One

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

(2013) Xueqi Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

(2012) Neil M. Fournier et al.   NEUROPHARMACOLOGY

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)

(2011) M. Merk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

(2010) S. E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell fate decisions are specified by the dynamic ERK interactome

(2009) Alex von Kriegsheim et al.   NATURE CELL BIOLOGY

Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons

(2008) B. Hausott et al.   NEUROSCIENCE

Ser-59 is the major phosphorylation site in αB-crystallin accumulated in the brains of patients with Alexander's disease

(2003) Kanefusa Kato et al.   JOURNAL OF NEUROCHEMISTRY