Effect of Chronic Stress Present in Fibroblasts Derived from Patients with a Sporadic Form of AD on Mitochondrial Function and Mitochondrial Turnover

Defective Autophagy and Mitophagy in Aging and Alzheimer’s Disease

(2021) Michael Tran et al.   Frontiers in Neuroscience

Links between mitochondrial retrograde response and mitophagy in pathogenic cell signalling

(2021) Daniela Strobbe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Adaptation of mitochondrial network dynamics and velocity of mitochondrial movement to chronic stress present in fibroblasts derived from patients with sporadic form of Alzheimer’s disease

(2021) Karolina Drabik et al.   FASEB JOURNAL

Mitochondrial ROS and Mitophagy: A Complex and Nuanced Relationship

(2020) James H. Schofield et al.   ANTIOXIDANTS & REDOX SIGNALING

Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2

(2020) Luisa Galla et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease

(2020) Chenglong Xie et al.   Frontiers in Cell and Developmental Biology

Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease

(2020) Munehiro Kitada et al.   Frontiers in Physiology

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

(2019) Evandro F. Fang et al.   NATURE NEUROSCIENCE

Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities

(2019) Judit M. Perez Ortiz et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Good and the Bad of Mitochondrial Breakups

(2019) Hans-Georg Sprenger et al.   TRENDS IN CELL BIOLOGY

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients

(2018) Julian H. Birnbaum et al.   Stem Cell Research

A Cell Model for the Initial Phase of Sporadic Alzheimer's Disease

(2018) Carola Stockburger et al.   JOURNAL OF ALZHEIMERS DISEASE

Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics

(2018) Jarosław Walczak et al.   FASEB JOURNAL

Mitochondrial retrograde signaling in the nervous system

(2017) Rachel J. Hunt et al.   FEBS LETTERS

Mitochondrial biogenesis in neurodegeneration

(2017) P. Andy Li et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease

(2017) Patricia Martín-Maestro et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial fusion, fission, and mitochondrial toxicity

(2017) Joel N. Meyer et al.   TOXICOLOGY

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

(2017) David Sebastián et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Alzheimer's disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

(2016) Leide dos Santos Picanç et al.   CURRENT MEDICINAL CHEMISTRY

Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes

(2015) Fernanda Marques da Cunha et al.   Oxidative Medicine and Cellular Longevity

Alzheimer's disease research and development: a call for a new research roadmap

(2014) Howard H. Feldman et al.   Annals of the New York Academy of Sciences

Lessons from a Failed γ-Secretase Alzheimer Trial

(2014) Bart De Strooper   CELL

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age

(2013) Andrew W Ferree et al.   Autophagy

MitoTimer

(2013) Genaro Hernandez et al.   Autophagy

Cellular metabolic and autophagic pathways: Traffic control by redox signaling

(2013) Matthew Dodson et al.   FREE RADICAL BIOLOGY AND MEDICINE

SOD2 in mitochondrial dysfunction and neurodegeneration

(2013) James M. Flynn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Animal Models of Alzheimer Disease

(2013) F. M. LaFerla et al.   Cold Spring Harbor Perspectives in Medicine

Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype

(2012) Mahesh Ramamoorthy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

(2012) Mason A. Israel et al.   NATURE

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

(2010) Kei Okatsu et al.   GENES TO CELLS

Cell cycle regulation distinguishes lymphocytes from sporadic and familial Alzheimer's disease patients

(2010) Emilia Bialopiotrowicz et al.   NEUROBIOLOGY OF AGING

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients

(2008) Xinglong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING