Ferritin H deficiency deteriorates cellular iron handling and worsens Salmonella typhimurium infection by triggering hyperinflammation

Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series

(2020) Achille Aouba et al.   ANNALS OF THE RHEUMATIC DISEASES

Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis

(2020) George Dimopoulos et al.   Cell Host & Microbe

Prevalence and Predictive Value of Anemia and Dysregulated Iron Homeostasis in Patients with COVID-19 Infection

(2020) Rosa Bellmann-Weiler et al.   Journal of Clinical Medicine

Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis

(2020) Petek Eylul Taneri et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Linkage of alterations in systemic iron homeostasis to patients’ outcome in sepsis: a prospective study

(2020) Anna Brandtner et al.   Journal of Intensive Care

IL‐1 Receptor Antagonist, Anakinra, Prevents Myocardial Dysfunction in a Mouse Model of Kawasaki Disease Vasculitis and Myocarditis

(2019) Mark Gorelik et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Impact of Dietary Transition Metals on Host-Bacterial Interactions

(2018) Christopher A. Lopez et al.   Cell Host & Microbe

Iron and innate antimicrobial immunity—Depriving the pathogen, defending the host

(2018) Manfred Nairz et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection

(2018) Vineel P. Reddy et al.   Frontiers in Immunology

Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome

(2018) David Haschka et al.   MOVEMENT DISORDERS

Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells

(2017) Linda Quatrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blockage of caspase-1 activation ameliorates bone marrow inflammation in mice after hematopoietic stem cell transplantation

(2016) Jianlin Qiao et al.   CLINICAL IMMUNOLOGY

Activation of the NLRP3 inflammasome by cellular labile iron

(2016) Kyohei Nakamura et al.   EXPERIMENTAL HEMATOLOGY

Lipocalin 2 drives neutrophilic inflammation in alcoholic liver disease

(2016) Verena Wieser et al.   JOURNAL OF HEPATOLOGY

Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling

(2016) Jing Li et al.   Oncotarget

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

(2015) Manfred Nairz et al.   Cell Host & Microbe

The Iron age of host-microbe interactions

(2015) M. P. Soares et al.   EMBO REPORTS

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria

(2015) David Haschka et al.   Metallomics

Exploiting host immunity: the Salmonella paradigm

(2015) Judith Behnsen et al.   TRENDS IN IMMUNOLOGY

Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock

(2014) Tom Vanden Berghe et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

Iron at the interface of immunity and infection

(2014) Manfred Nairz et al.   Frontiers in Pharmacology

The IRP/IRE system in vivo: insights from mouse models

(2014) Nicole Wilkinson et al.   Frontiers in Pharmacology

D-Light on promoters: a client-server system for the analysis and visualization of cis-regulatory elements

(2013) Josef Laimer et al.   BMC BIOINFORMATICS

The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: Insights into the potential of various iron therapies to induce oxidative and nitrosative stress

(2013) Taija S. Koskenkorva-Frank et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mycobacterium avium Infection Induces H-Ferritin Expression in Mouse Primary Macrophages by Activating Toll-Like Receptor 2

(2013) Sandro Silva-Gomes et al.   PLoS One

Mechanisms of Mammalian Iron Homeostasis

(2012) Kostas Pantopoulos et al.   BIOCHEMISTRY

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption

(2010) Liviu Vanoaica et al.   Cell Metabolism

Taming the Elephant: Salmonella Biology, Pathogenesis, and Prevention

(2010) H. L. Andrews-Polymenis et al.   INFECTION AND IMMUNITY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

Toll-like receptor 4 signalling through MyD88 is essential to controlSalmonella entericaserovar Typhimurium infection, but not for the initiation of bacterial clearance

(2009) Suzanne Talbot et al.   IMMUNOLOGY

Infiltrating CD11b+CD11c+cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice

(2009) Nirmala Parajuli et al.   INTERNATIONAL JOURNAL OF CANCER

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells

(2008) Richard G. Ruddell et al.   HEPATOLOGY